Team:Debrecen Hungary/Team
From 2011.igem.org
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Nuclear hormone receptors (NHRs) are ligand activated transcription factors. They are able to regulate the expression of their target genes by direct DNA-binding, in a ligand-dependent manner. NHRs bear high homology to each other and are modular into distinct regions: N-terminal regulatory region, DNA-binding domain, a Hinge region, Ligand binding domain (LBD) and a C-terminal region. Some Nematode NHRs can be activated by extracted oil contamination of the soil so they can use as possible oil sensors in the future. Zinc finger motifs are the tools of NHRs to bind DNA and regulate gene expression directly. These tiny elements can be tested as direct gene regulators. Controlled gene induction can also lead to programmed cell death which is a less harmful tool in order to quit non-functionable cells. | |
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Debrecen
Debrecen is one of the most vivid and coziest nooks in Hungary: this city is a unique and outstanding whirlpool of a dynamic cultural and intellectual heritage and of an effective and successful economic life. The centuries’ old traditions and the most recent technical and scientific innovations enhancing each other make Debrecen a nationally and internationally renowned city.
This lively city in the heart of the Carpathian Basin awaits the visitors with a cornucopia of programs and events, from a number of excellent art exhibitions, folk programs to many sports and leisure events. The outstanding collections of the local museums, the historical monuments of the city or the various and imposing programs of local folk traditions enchant all visitors who wish to explore the marvels of Debrecen: choir festivals, folk festivals, carnivals, breath-taking exhibitions, fairs offer their programs and goods for the visitors. At the same time Debrecen, which is a university centre, is also a place for conferences and scientific meetings, and this serves the active and organic cooperation of the city’s economic, scientific, educational and cultural life.
This culturally and scientifically active life is combined with a splendid leisure and wellness sphere as well: the recently renovated Mediterranean Aqua Park and the charming Zoo in the centre of the romantic Great Forest offer excellent time for the whole family, while the Aquaticum Wellness and Spa Resort designs exclusive health treatments and wellness care programmes for the visitors as Debrecen is one of the largest centres of mineral thermal water in Europe. This leisure life is enriched by the active sport life of the city: Debrecen has been hosting a number of national and international sports events from national championships to European and World championships. For the lovers of rural country life the Erdőspuszta territories and Hortobágy is a must to visit, because the calm and enchanting atmosphere is an excellent basis for relaxation, while those who seek pleasures in fishing, hunting and riding may also enjoy the region.
Thus, this city in the eastern periphery of the country is an unparalleled place – not only because of the flourishing cultural, scientific and social life but because of the dynamic economic and industrial traditions as well, which has established an outstanding and marvellous atmosphere in Debrecen.