Quorum Sensing Achievements

Optimization of the device

As the modelling part shows our models for Quorum Sensing allowed us to have a visual representation of our entire device. This modelling highlighted the diffusion of the quorum sensing molecule.

Figure 4: Animation generated through MATLAB for visual representation of our models and the complete deterministic simulation

Decreasing the accuracy of the measure, quorum sensing diffusion is a problem for our system. To fixe this problem, we decided to developed a device with channel containing each of them a different IPTG concentration but the same aTc concentration.

Figure 5: First prototype of the device

This kind of device allows us to limit the diffusion of quorum sensing at one channel. Of course the measure won't be a unique concentration, but a range of concentration. However, the problem posed by quorum sensing diffusion would disrupt the measure more than the channel device (if there are a sufficent number of channel and a small enough IPTG step).

Test of the quorum sensing system