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Team:ZJU-China/Modeling/Biobrick
From 2011.igem.org
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Modeling|biobrick |
This model is used for simulating the behavior of three genetic circuits we designed
Overview
Modeling
Results
Introduction
abstract:
We will model our gene regulatory networks using Michaelis-Menten enzymatic kinetics,together with the usual rules of reaction kinetics. The resulting models, when spatial
effects are neglected, are given in terms of ordinary differential equations describing the
rate of change of the concentrations of gene products and proteins. A key component of all
these models is the Hill function, used to describe the transcription phase. The presence of
this highly nonlinear function, whilst accurately modeling the network, inevitably leads to
restrictions on the analytical tools available to understand and predict the
dynamics.
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