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Team:Penn State/Project
From 2011.igem.org
Contents |
Overall project: Bacterial Dosimeter
Radiation of one form or another is a constant presence throughout our every day lives. Radiation, or the transmission and absorption of energy over a given distance, has proven an invaluable technology useful in applications for everything from heating our food to diagnosing and treating diseases.
All types of radiation can be divided into two categories: non-ionizing and ionizing. Non-ionizing radiation (consisting of radio, micro, infrared, and visible electromagnetic waves) contains less energy and has a relatively small effect on living organisms that has only recently been studied. Ionizing radiation, however, contains a much greater amount of energy capable of ionizing atoms which can lead to harmful effects on living tissue. This category of radiation encompasses alpha and beta decay as well as neutron, X-ray, and gamma radiation.
Project Details
The genetic circuit we designed focuses on the DNA damage-sensitive lambda phage lytic-lysogenic cycle switch followed by a rapid response reporter similar to the immobilized fusion enzyme system pioneered by the Imperial College of London 2010 iGEM team. An initial design of our system is illustrated below.
Part 2
The Experiments
Part 3
Results
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