Team:UPO-Sevilla/Project/Improving Flip Flop/Modeling/Introduction

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Modeling

Introduction

In this chapter we model the modified toggle switch

To start, we include to this analysis the processes described at ‘Basic Bistable – Modeling’.

TRANSCRIPTION: RNAp + Promoter → RNAp + Promoter + mRNA

The mRNA production will be described using Michaelis-Menten kinetics:

TRANSLATION: mRNA + Ribosomes → mRNA + Ribosomes + Repressor

The Repressor production will be also modeled using Michaelis-Menten kinetics:

REPRESSION:

Promoter + n · Repressor → Promoter_Repressorn