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Team:UNAM-Genomics Mexico/Modeling
From 2011.igem.org
Inside the Phaseolus vulgaris root nodules, Rhizobium etli enjoys a protected niche. However the protection provided by the plant is given solely in exchange for the nitrous compounds produced by the bacteria. For this it is very important to understand how hydrogen production will affect nitrogen fixation in the bacteria. That is the question we aim to answer with our modeling efforts.
Flux Balance Analysis
R. elti's metabolism inside the nodule is fairly constant. This homeostatic state is one of the assumptions done when modeling metabolism with Flux Balance Analysis. We have deffined three main metabolic compartments: cytosol, periplasm and extracellular compartment.
Cellular Automaton
To asses how individual bacterium interact with each other we'll use cellular automaton based models.
Game Theory
The niche adecuation is our final goal. To model it we'll use the prize and penalization perspective of the game theory branch of math.
