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Team:KULeuven/Discussion
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Sound/vibration sensor system for E.coli
--Erwinswinnen 09:25, 8 June 2011 (CDT)
presence of mechanosensors MscL/MscS in E.coli
use of human hair cells?
--> Koen: Is it recommended to work with E.coli? We can also use human hair cells, then we could make a direct sound sensor in stead of a pressure sensor.
Good websites with the basics of hearing: http://www.ks.uiuc.edu/Research/hearing/ and http://www.beyonddiscovery.org/content/view.page.asp?I=259
In the ear the crucial point is converting the mechanical stimulation of the hair cells into a membrane electric potential which leads to neural signalling. Maybe it is possible to visualize this electic potential and make a correlation between the frequency of the sound and the colour we use. For example a blue colour is generated when the frequency of the sound is X MHz. Another advantage of working with human hair cells is having much more previous research literature. Now we only need the time to explore it ... ;-)
It is impossible to detect sound with only one hair cell (like proposed in my previous mail), of course you need the whole ear organ. However we can still use hair cells for detecting pressure pulses but E. coli is also possible.
--> Jonas: The advantage of e. coli is that it's easy to work with + the registry is mainly aimed at this bacterium.
