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From 2011.igem.org

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Google Insights suggests the most number of searches for “synthetic biology” is from India. Yo! Veni, Vidi, Veci! So what do we have in store for iGEM this year? Gene expression systems in many organisms have been understood and manipulated into useful constructs by many iGEM teams in the past years. We are trying to optimize the response to a number of stimuli and hope to achieve a super sensor. The most interesting two component signal transduction system of prokaryotes which essentially involves a histidine kinase and a response regulator protein is our guinea pig.

We are trying to model a system which can identify 3 different inputs and process using the same response element. A window of responses will be identified, both experimentally and computationally and then the model can be extrapolated to n different inputs. Watch this space for more updates…