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From 2011.igem.org

Artificial Innate Immunity System(AIIS)

    From mid May to June, enteropathogenic E.coli brings a big panic to many different European countries. Why such an ordinary bacteria as E.coli can lead to a clinical catastrophe and kill a lot of people? The answer may be complicate, but the most important reason is that we can not find out the pathogens rapidly and can not apply the effective treatments.

Figure1.Enteropathogenic Escherichia coli adhereing to cultured human intestinal cells (brown)

    To solve this problem, we try to use the normal E.coli, which keep the symbiotic relationship with us humanbeings, to be a safety weapon to defend ourselves against pathogens.