Team:Grenoble/Projet/Design/toggle

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Grenoble 2011, Mercuro-Coli iGEM

The Toggle Switch allows our bacterial strain to switch between one of the two different behaviors (Receiver or Secretor) depending on the predominant concentration in the external medium: IPTG or Hg.

We take into account two proteins repressing (CinI/CinR) each other's expression (pLac/pMerT). We create the fundaments of a toggle system that can switch when using two inducers in the medium: IPTG and Hg.