Team:UNAM-Genomics Mexico/Modeling/MM

From 2011.igem.org

Revision as of 08:30, 26 September 2011 by Hmedina (Talk | contribs)

UNAM-Genomics_Mexico


Plasmid Stability

So we decided to model the stability of our working plasmid. The data we had were the surviving colony counts after a certain time period. Therefore, we were interested in the probability of loss for the plasmid, at the moment of celular division. We assumed this to be time-discrete, and equal-probability per iteration.

Results

Applying a Markov model to the stability, with <X> the event of plasmid keeping for passage of <t> to <t+1>, we found a value of P(X=True)=0.999774 and consequently P(X=False)=0.000226.

Retrieved from "http://2011.igem.org/Team:UNAM-Genomics_Mexico/Modeling/MM"