Team:Groningen/Modeling/Modeling Blog

From 2011.igem.org

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(May 19th 2011)
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==May 19th 2011==
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==Jaap Oosterbroek - May 24th 2011==
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Tested our bistabilety analiser today and it worked like a charm. What it basically does is take a promotor description, a protein decay function and an rna halflife and predicts where (if any) the stable states of the sytem are goin to be. Afterwards you can use a full model to check how robust these points really are. To us that meant that we saw how extremly important it is to model the delay in transcription and translation.
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==Jaap Oosterbroek - May 19th 2011==
We decided to drop simbiolegy today. It does not offer us the functionalty we need and is simply to buggy for our purposes.
We decided to drop simbiolegy today. It does not offer us the functionalty we need and is simply to buggy for our purposes.
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Instead we will be continueing with the modelling library Jaap build last week. Maybe we can release on the wiki some time soon so other teams won't have to face up against all the awefull quircks of simbiolegy. But before that we need to clean it up a bit, and we are still in some dissagreement about some parts of it. Especially the trade-off between neat programming and effecientcy.
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Instead we will be continueing with the modelling library I build last week. Maybe we can release on the wiki some time soon so other teams won't have to face up against all the awefull quircks of simbiolegy. But before that we need to clean it up a bit, and we are still in some dissagreement about some parts of it. Especially the trade-off between neat programming and effecientcy.

Revision as of 08:23, 24 May 2011

Jaap Oosterbroek - May 24th 2011

Tested our bistabilety analiser today and it worked like a charm. What it basically does is take a promotor description, a protein decay function and an rna halflife and predicts where (if any) the stable states of the sytem are goin to be. Afterwards you can use a full model to check how robust these points really are. To us that meant that we saw how extremly important it is to model the delay in transcription and translation.

Jaap Oosterbroek - May 19th 2011

We decided to drop simbiolegy today. It does not offer us the functionalty we need and is simply to buggy for our purposes. Instead we will be continueing with the modelling library I build last week. Maybe we can release on the wiki some time soon so other teams won't have to face up against all the awefull quircks of simbiolegy. But before that we need to clean it up a bit, and we are still in some dissagreement about some parts of it. Especially the trade-off between neat programming and effecientcy.