Team:UST-Beijing/Team
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'''Advisors:''' | '''Advisors:''' | ||
- | *''' Advisor 1''': ChingSong*'''Advisor 2''': Our favorite | + | *''' Advisor 1''': ChingSong*'''Advisor 2''': Our favorite Huaizhang |
*'''Grad Student 1''': Our leader Hanzhong Ke | *'''Grad Student 1''': Our leader Hanzhong Ke | ||
Revision as of 06:26, 5 August 2011
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Who we are
Advisors:
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What we did
We using lacI DNA-binding domain and LXRbeta ligand-binding domain, we made an artificial bile acid receptor which can regulate expression of target gene within a natural lacI operon. As proof of principle, we demonstrate that regulation of bacteria gene expression by host eukaryocyte metabolites is achievable using chimeric nuclear receptors. Through directed molecular evolution, a harmonious signal network regulating metabolism of both prokaryocytes and their host eukaryocytes in the digestive tract is feasible.