Team:BU Wellesley Software

From 2011.igem.org

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<H1> Project Description </H1>
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Biological systems are composed of seemingly intractable sets of complex interactions.  Studying these interactions one at a time can be tedious and time consuming.  Our research introduces a recombinant method for studying these interactions more efficiently by designing custom “plasmid architectures” that allow the researcher to reconfigure different DNA parts within the plasmid.  Our specific design driver is the exploration of transcription factor interaction in tuberculosis.<br>  </P>
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While studying biology can be intractable, managing your lab should not.  Along with our custom plasmid architecture, we have developed a suite of software tools that not only automate the design process of these custom plasmids, but streamline the assembly of all DNA parts while keeping the members of the lab in sync via an electronic laboratory notebook.  By linking these tools to a central lab database, all of this information can be accessed from multiple devices and shared between lab members.  We hope that these tools will promote collaboration between labs and increase productivity within the synthetic biology community.<br></P>
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The Boston University/Wellesley College software team is focused on the creation of novel software tools and human-computer interfaces for synthetic biology. Our specific design driver is the exploration of transcription factor interaction in tuberculosis via the creation of custom "plasmid architectures" leveraging the transformative effects of recombinases. The computational foundation of this work is twofold (1) The development of new Clotho Apps for plasmid design, automated assembly, and laboratory management and (2) specific collaborative and interactive software experiences including electronic laboratory notebooks and touch surface design environments.
 

Revision as of 15:14, 15 July 2011


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Project Description

Biological systems are composed of seemingly intractable sets of complex interactions. Studying these interactions one at a time can be tedious and time consuming. Our research introduces a recombinant method for studying these interactions more efficiently by designing custom “plasmid architectures” that allow the researcher to reconfigure different DNA parts within the plasmid. Our specific design driver is the exploration of transcription factor interaction in tuberculosis.

While studying biology can be intractable, managing your lab should not. Along with our custom plasmid architecture, we have developed a suite of software tools that not only automate the design process of these custom plasmids, but streamline the assembly of all DNA parts while keeping the members of the lab in sync via an electronic laboratory notebook. By linking these tools to a central lab database, all of this information can be accessed from multiple devices and shared between lab members. We hope that these tools will promote collaboration between labs and increase productivity within the synthetic biology community.



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