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Team:WHU-China/Project/Modeling
From 2011.igem.org
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| - | <div style="font-size: | + | <div style="font-size:24px;font-style:Bold">The Gene Circuit </div> |
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This is our gene circuit designed to equip our E.coli with the ability to change color with time.</br> | This is our gene circuit designed to equip our E.coli with the ability to change color with time.</br> | ||
Revision as of 01:57, 29 October 2011
The Gene Circuit
This is our gene circuit designed to equip our E.coli with the ability to change color with time. The key players are LsrR and LsrK. The alternation of their expression results in the oscillating concentration of the reporter—GFP, and thus yield the periodically changing color. Theoretically, at the very beginning, LsrR is expressed and inhibits LsrK. After some time, LsrR inhibits itself and its concentration drops. Therefore LsrK has a chance to express and climbs due to its self enlarging. However, LsrK induces the reexpression of LsrR at the same time. In this way, their concentrations wave alternatively. C1’s function is to delay the oscillation and stabilize the system.
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