Team:NYMU-Taipei
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==<font size=5><font color=crimson>'''Tailoring Your Avatar'''</font></font>== | ==<font size=5><font color=crimson>'''Tailoring Your Avatar'''</font></font>== | ||
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<font size=3>Create wireless neuro-stimulator, focusing on achieving remote neuro-stimulation to minimize the invasion and damage to the neuron</font> | <font size=3>Create wireless neuro-stimulator, focusing on achieving remote neuro-stimulation to minimize the invasion and damage to the neuron</font> | ||
Revision as of 19:26, 28 October 2011
Tailoring Your AvatarGoal Create wireless neuro-stimulator, focusing on achieving remote neuro-stimulation to minimize the invasion and damage to the neuron
Optogenetics, the latest neuroscientific method, has improved specificity for stimulating certain cell types of neurons, reversible bi-directional stimulation, and elevated spatiotemporal precision. However, to achieve neuronal network stimulation, light cables are still needed, leaving long-standing annoying issues regarding immune responses unresolved.
To achieve this goal, we use a species of magnetic bacteria, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: MinC, a division inhibitor, INV, a gene for invasion and LLO, a gene for facilitated escape from phagosomes.
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