Team:Edinburgh/Modelling
From 2011.igem.org
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- | + | Possible '''models'''... | |
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+ | ==Evolutionary analysis of cell-display vs. secretion?== | ||
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+ | One potential benefit of attaching enzymes to the cell surface rather than secreting them into the ether is that any mutations that increase enzyme efficiency will specifically benefit the cell with the mutation, as the increased sugar yield will be physically present at the cell. The mutation will thus confer a fitness advantage, potentially allowing it to take over the culture. | ||
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+ | By contrast, if a cell produces a ''secreted'' protein that is of higher efficiency, it will disperse and benefit random cells in the culture. | ||
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{{:Team:Edinburgh/Template:Navbox}} | {{:Team:Edinburgh/Template:Navbox}} |
Revision as of 12:45, 1 July 2011
Possible models...
Evolutionary analysis of cell-display vs. secretion?
One potential benefit of attaching enzymes to the cell surface rather than secreting them into the ether is that any mutations that increase enzyme efficiency will specifically benefit the cell with the mutation, as the increased sugar yield will be physically present at the cell. The mutation will thus confer a fitness advantage, potentially allowing it to take over the culture.
By contrast, if a cell produces a secreted protein that is of higher efficiency, it will disperse and benefit random cells in the culture.
This was the old Navbox for Edinburgh; now it's obsolete...
- Edinburgh 2011
- Project documentation: Project - BioSandwich - Parts - Modeling - Lab Notebook - Safety - Team - Attributions
- Pages for members: Wiki Watch - Useful Links - Sequences - Primers - Practices - Official Profile (has email addresses)
- (edit this navigation box)