Team:Grenoble/Projet/Design

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<a href="https://2011.igem.org/Team:Grenoble/Projet/design/regulation" ><img class="icon" src="https://static.igem.org/mediawiki/2011/6/6e/Icon_rsma.png"/></a>
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<big><big><a href="https://2011.igem.org/Team:Grenoble/Projet/regulation" class="menu">Post-transcriptional regulation :</a></big></big><br/>
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<br/><big><big><a href="https://2011.igem.org/Team:Grenoble/Projet/regulation" class="menu">Post-transcriptional regulation :</a></big></big><br/>
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<a  href="https://2011.igem.org/Team:Grenoble/Projet/Design/regulation" class="menu">A post-transcriptional regulation system</a><br/>
<a  href="https://2011.igem.org/Team:Grenoble/Projet/Design/regulation" class="menu">A post-transcriptional regulation system</a><br/>

Revision as of 16:27, 26 October 2011

Grenoble 2011, Mercuro-Coli iGEM


Biology

Based on Gardner's [1] work and Predator–Prey ecosystem [2], we designed the following circuit.



It can be divided into four parts: the Toggle Switch, the Quorum Sensing, the Coloration and the post-transcriptional regulation.



Toggle Switch:




Quorum Sensing :
The Quorum Sensing
Coloration


Post-transcriptional regulation :
A post-transcriptional regulation system
The RsmA translational regulation system
The rpoS regulation system



References :

  1. GARDNER'S WORK: "Construction of a genetic toggle switch in Escherichia coli", Timothy S. Gardner, Charles R. Cantor and James J. Collins
  2. PREY AND PREDATOR: "A synthetic Escherichia coli predator–prey ecosystem", Frederick K Balagadd, Hao Song, Jun Ozaki, Cynthia H Collins, Matthew Barnet, Frances H Arnold, Stephen R Quake and Lingchong You