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Team:Grenoble/Projet/Results/Quorum
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<div class="blocbackground" id="Optimization"> | <div class="blocbackground" id="Optimization"> | ||
<h2>Optimization of the device</h2> | <h2>Optimization of the device</h2> | ||
| + | <p> | ||
| + | As the modelling part shows our models for Quorum Sensing allowed us to have a visual representation of | ||
| + | our entire device. This modelling highlighted the diffusion of the quorum sensing molecule. | ||
| + | </p> | ||
| + | |||
| + | <center><a href="https://static.igem.org/mediawiki/2011/9/91/Animatedplate.gif"><img src="https://static.igem.org/mediawiki/2011/9/91/Animatedplate.gif" class="centerwide"/></a><br/> | ||
| + | <div class="legend"><strong>Figure 4:</strong> Animation generated through MATLAB for visual representation of our models and the complete deterministic simulation</div> | ||
| + | </center> | ||
| + | <p> | ||
| + | Decreasing the accuracy of the measure, quorum sensing diffusion is a problem for our system. To fixe this problem, | ||
| + | we decided to developed a device with channel containing each of them a different IPTG concentration but | ||
| + | the same aTc concentration. | ||
| + | </p> | ||
| + | |||
| + | <center><a href="https://static.igem.org/mediawiki/2011/a/a2/IMG_5964_%28copie%29.JPG"><img src="https://static.igem.org/mediawiki/2011/a/a2/IMG_5964_%28copie%29.JPG" class="centerwide"/></a><br/> | ||
| + | <div class="legend"><strong>Figure 5:</strong> First prototype of the device</div> | ||
| + | </center> | ||
| + | <p> | ||
| + | This kind of device allows us to limit the diffusion of quorum sensing at one channel. Of course the measure won't be a unique concentration, but a range of concentration. | ||
| + | However, the problem posed by quorum sensing diffusion would disrupt the measure more than the channel device (if there are | ||
| + | a sufficent number of channel and a small enough IPTG step). | ||
| + | </p> | ||
| + | |||
</div> | </div> | ||
| - | <div class="blocbackground" id=" | + | <div class="blocbackground" id="Test_QS"> |
<h2>Test of the quorum sensing system</h2> | <h2>Test of the quorum sensing system</h2> | ||
</div> | </div> | ||
Latest revision as of 21:21, 24 October 2011
Quorum Sensing Achievements
Optimization of the device
As the modelling part shows our models for Quorum Sensing allowed us to have a visual representation of our entire device. This modelling highlighted the diffusion of the quorum sensing molecule.
Decreasing the accuracy of the measure, quorum sensing diffusion is a problem for our system. To fixe this problem, we decided to developed a device with channel containing each of them a different IPTG concentration but the same aTc concentration.
This kind of device allows us to limit the diffusion of quorum sensing at one channel. Of course the measure won't be a unique concentration, but a range of concentration. However, the problem posed by quorum sensing diffusion would disrupt the measure more than the channel device (if there are a sufficent number of channel and a small enough IPTG step).
