Team:Valencia

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Revision as of 14:27, 1 September 2011

Water Colicin Cleaner: disinfected water by E. coli

Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.

We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality. W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.

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-===Description of the project===
+<br>
+<br>
+<br>
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+<br>
+==Water Colicin Cleaner: disinfected water by <i>E. coli</i>==
 {|align="justify"
-|The aim of our team is to develop a '''biological alternative for disinfecting contaminated water using synthetic biology'''. We will '''kill targeted pathogens''' by means of '''antimicrobial peptides''' in ''Escherichia coli''. The activity of these proteins will be controlled by a '''biological pH-stat''' that will use cyanobacteria to control pH.
+|Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in <i>Escherichia coli</i>. As a proof of concept we have chosen to aim for enterobacteria, focusing on <i>E. coli</i> contaminated water, as a proxy of fecal water. The cleaning of <i>E. coli</i> will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
+We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
-We plan to deliver a DIY kit that will help people that struggle to find '''pathogen-free drinking water avoiding important diseases''', such as cholera, diarrhea and typhoid fever, ending in more than 2 million deaths in the last year according to the ''WHO Guidelines for Drinking-Water Quality'' (World Health Organization, 2011).
+W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.
 |[[Image:Valencia logo face.png|right]]
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