Team:BU Wellesley Software/Notebook/CaseyNotebook

From 2011.igem.org

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This summer the Wellesley HCI Lab worked on re-implementing an old system, G-nome Surfer 2.0, new and improved and optimized for prokaryotic genomes. To make an application practical for researching prokaryotic genomes we had to create a number of new interaction styles for dealing with navigation of a circular chromosome. Working on the system I worked on the new chromosome wheel, the publications system, the new primer designer and the associated BLAST.  
This summer the Wellesley HCI Lab worked on re-implementing an old system, G-nome Surfer 2.0, new and improved and optimized for prokaryotic genomes. To make an application practical for researching prokaryotic genomes we had to create a number of new interaction styles for dealing with navigation of a circular chromosome. Working on the system I worked on the new chromosome wheel, the publications system, the new primer designer and the associated BLAST.  
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'''Implementation'''
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G-Nome Surfer Pro is written in C# using the Microsoft SDK for use on the Microsoft Surface. After much trial and error we re-implemented many parts of the system using data binding which allows a complete separation of state and logic. (more information about data binding can be found on MSDN [http://msdn.microsoft.com/en-us/library/ms752347.aspx here])
'''Navigation'''
'''Navigation'''
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The central chromosome wheel went through several iterations before arriving at the final simple rotation model we currently use.  
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The central chromosome wheel went through several iterations before arriving at the final simple rotation model we currently use. An early implementation allowed for zooming through use of a pair of arms (like in the early paper prototype.) Like many of the early user controls the arms involved a fair amount of hacking through the presentation logic and item templates through the .xaml files. 
'''Publications'''
'''Publications'''

Revision as of 15:26, 3 August 2011

This summer the Wellesley HCI Lab worked on re-implementing an old system, G-nome Surfer 2.0, new and improved and optimized for prokaryotic genomes. To make an application practical for researching prokaryotic genomes we had to create a number of new interaction styles for dealing with navigation of a circular chromosome. Working on the system I worked on the new chromosome wheel, the publications system, the new primer designer and the associated BLAST.

Implementation G-Nome Surfer Pro is written in C# using the Microsoft SDK for use on the Microsoft Surface. After much trial and error we re-implemented many parts of the system using data binding which allows a complete separation of state and logic. (more information about data binding can be found on MSDN [http://msdn.microsoft.com/en-us/library/ms752347.aspx here])

Navigation The central chromosome wheel went through several iterations before arriving at the final simple rotation model we currently use. An early implementation allowed for zooming through use of a pair of arms (like in the early paper prototype.) Like many of the early user controls the arms involved a fair amount of hacking through the presentation logic and item templates through the .xaml files.

Publications

Primer Design

not hooked up to live data just yet.
earliest functional primerGenie prototype.


BLASTing

H37RV is the only one we needed.
early BLAST visualization showing multiple tuberculosis genomes.