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Team:SJTU-BioX-Shanghai
From 2011.igem.org
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<div class="cell"><li>TEAM</li></div> | <div class="cell"><li>TEAM</li></div> | ||
| - | <div class="cell"><li> | + | <div class="cell"><li>PARTS</li></div> |
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<div class="cell"><li>MODELING</li></div> | <div class="cell"><li>MODELING</li></div> | ||
<div class="cell"><li>NOTEBOOK</li></div> | <div class="cell"><li>NOTEBOOK</li></div> | ||
<div class="cell"><li>SAFETY</li></div> | <div class="cell"><li>SAFETY</li></div> | ||
<div class="cell"><li>HUMAN PRACTICE</li></div> | <div class="cell"><li>HUMAN PRACTICE</li></div> | ||
| + | <div class="cell"><li>ACKNOWLEDGEMENTS</li></div> | ||
<div class="cell"><li>SPONSORS</li></div> | <div class="cell"><li>SPONSORS</li></div> | ||
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Revision as of 07:28, 18 July 2011
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A Synthetic-Biological System Controlling Translation Process
2011 SJTU-BioX iGEM team is designing a system in which we will be able to control the expression of the target gene on the level of translation. Our system has provided a brand-new approach that can be universally applied to any protein expression system. In our system we can strictly switch on/off the translation of the target gene; we can selectively translate a part of the whole open reading frame; we can also shift certain amino acid residues to any of the 20 possible alternatives without altering the sequence of the gene. Our significant design offers a multi-purpose and universal way to regulate gene expression on translation level, to selectively express part of a gene, to introduce mutation to the target position of a protein and to study the important residues or domains of the target protein.
