Team:Grenoble/Safety
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+ | The system we develop needs to be kept off until we want to induce it. In order to achieve that, we develop a post-transcriptional switch mechanism. This system, extracted from Pseudomonas aeruginosa, is highly similar to another one of E. coli. The later involve the management of numerous genes including virulence factors. The bacteria we use don’t have any gene coding for virulence factor so the risk doesn’t exist with our strain. | ||
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<li><strong>Is there a local biosafety group, committee, or review board at your institution? </strong> | <li><strong>Is there a local biosafety group, committee, or review board at your institution? </strong> |
Revision as of 19:22, 14 July 2011
TEAM:Grenoble
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Manipulation of living organism allows producing artificial form of life and metabolism. These modifications, although well controlled, require application of the precautionary principle. Caution involves the implementation of different blocking to limit the propagation of these organisms in the nature:
Through the iGEM competition, we face to the risks of synthetic biology. So it’s important to deal with safety issues our project could cause.
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We are making a device that can quantify a component in water, such as heavy metals pollutants. Two models are being developed. One of them involves the use of the Mer sensor. We therefore need to use mercury to test this system. These raise the environmental issue of the toxic waste management. Liquid having Mercury or tips and dishes that are in contact with this toxic are kept in specials bins. This rubbish bin is then given to a society specialized into toxic waste treatment. A slip monitoring is sign up by every organism that is involved into the production, transportation and treatment of the toxic waste. When the later is cremated, the producer of the waste receive and attestation that must be kept as a proof of the appropriate treatment. The system we develop needs to be kept off until we want to induce it. In order to achieve that, we develop a post-transcriptional switch mechanism. This system, extracted from Pseudomonas aeruginosa, is highly similar to another one of E. coli. The later involve the management of numerous genes including virulence factors. The bacteria we use don’t have any gene coding for virulence factor so the risk doesn’t exist with our strain. |
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