Team:NYMU-Taipei/Our institute

From 2011.igem.org

(Difference between revisions)
Line 10: Line 10:
*[https://2011.igem.org/Team:NYMU-Taipei/optomagnetic-design Optomagnetic Design]
*[https://2011.igem.org/Team:NYMU-Taipei/optomagnetic-design Optomagnetic Design]
**Bridge magnetics and optogenetics
**Bridge magnetics and optogenetics
-
*[https://2011.igem.org/Team:NYMU-Taipei/immunological-solution Immunological Solution]
+
*[https://2011.igem.org/Team:NYMU-Taipei/immunological-solution NeuroSymbiosis]
**Make magnetic bacteria symbiosis with glia cell
**Make magnetic bacteria symbiosis with glia cell
</font>
</font>

Revision as of 12:11, 28 October 2011

  • Our design

To achieve this goal, we use a species of magnetic bacteria, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: MinC, a division inhibitor, INV, a gene for invasion and LLO, a gene for facilitated escape from phagosomes.


  • Our design is made up of the following two devices:

  • Achievements

  • 1.We designed a new cloning vector of AMB-1 which is compatible with common biobricks, make it easier for igemers to clone magnetic bacteria AMB-1.
  • 2.We submitted over 60 parts to the registry, which can be used for application magnetic enlightment, cloning AMB-1, Symbiosis with Human cell.
  • 3.We designed helical anti-membrane protein CHAMP for mms13, separating the two helices of the magnetite binding protein mms13, making it flexible for the use of magnetic field in iGEM.
  • 4.We removed a PstI site of the part BBa_K299806, a part which expresses the MinC protein. We improved the compacity of this part.
  • 5.We designed a free online software, which provides an automated ONE-STEP primer design service of BioBricks for iGEM.
  • Our institute
  • The official web pages of our school - National Yang Ming University (NYMU):
    • [http://web.ym.edu.tw/front/bin/home.phtml in Chinese]
    • [http://nymu-e.web.ym.edu.tw/front/bin/home.phtml in English]
  • Follow the two links below to see The Beauty of NYMU
    • [http://issue.ym.edu.tw/cia/new/ Take a panoramic scenery view of our university]
    • [http://issue.ym.edu.tw/cia/new/tw/ym720.html Take a tour of our university]

Retrieved from "http://2011.igem.org/Team:NYMU-Taipei/Our_institute"