Team:WashU/Modeling
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- | The pathway for producing beta-carotene as shown in "High-Level Production of Beta-Carotene in Saccharomyces cerevisiae by Successive Transformation with Carotenogenic Genes from Xanthophyllomyces dendrorhous" by Verwaal, Rene et. Al. Yeast naturally produce GGPP but no other intermediates in beta-carotene pathway, crtYB and crtI are needed to to complete the pathway for beta-carotene production. Notice crtYB codes for two proteins needed in the pathway. CrtE further improves beta-carotene production as it aides in the production of the starting product, GGPP. | + | The pathway for producing beta-carotene as shown in "''High-Level Production of Beta-Carotene in Saccharomyces cerevisiae by Successive Transformation with Carotenogenic Genes from Xanthophyllomyces dendrorhous''" by Verwaal, Rene et. Al. Yeast naturally produce GGPP but no other intermediates in beta-carotene pathway, crtYB and crtI are needed to to complete the pathway for beta-carotene production. Notice crtYB codes for two proteins needed in the pathway. CrtE further improves beta-carotene production as it aides in the production of the starting product, GGPP. |
Revision as of 01:47, 28 September 2011
Modeling
The pathway for producing beta-carotene as shown in "High-Level Production of Beta-Carotene in Saccharomyces cerevisiae by Successive Transformation with Carotenogenic Genes from Xanthophyllomyces dendrorhous" by Verwaal, Rene et. Al. Yeast naturally produce GGPP but no other intermediates in beta-carotene pathway, crtYB and crtI are needed to to complete the pathway for beta-carotene production. Notice crtYB codes for two proteins needed in the pathway. CrtE further improves beta-carotene production as it aides in the production of the starting product, GGPP.
The pathway for producing beta-ionone from beta-carotene. This process only involves the expression of one gene, CCD, which codes for enzymatic oxidative cleavage 1 and 2, which cleaves the ends of beta-carotene to produce two beta-ionone molecules.