Team:UNAM-Genomics Mexico/Project

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Revision as of 06:48, 25 September 2011

UNAM-Genomics_Mexico



Abstract


<img src="Unamgenomics5.jpg" width="612" height="459" align="top">

<img src="Unamgenomicsproject1.jpg" width="612" height="459" align="absmiddle">

<img src="Unamgenomicsteam1.jpg" width="612" height="459" align="absmiddle">

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<img src="Unamgenomics5.jpg" width="612" height="459" align="absmiddle">

<img src="Unamgenomicsteam3.jpg" width="612" height="459" align="absmiddle">


Among the biological systems that produce hydrogen, the most efficient ones achieve it through reactions catalyzed by enzymes with iron-sulfur clusters which require hypoxic microenvironments to work. The bacterium Rhizobium etli, during its symbiotic relationship with the common bean Phaseolus vulgaris, can transform nitrogen gas into ammonia in a process called nitrogen fixation. In exchange the plant provides the bacteria with carbon sources and a protected niche inside its root, where Rhizobium etli reaches a hypoxic state. We will exploit this microenvironment to produce hydrogen in Rhizobium etli introducing a pathway assembled with elements from Clostridium acetobutylicum, Desulfovibrio africanus and Chlamydomonas reinhardtii, while maintaining nitrogen fixation. The two goals of our project are to make Rhizobium etli a powerful agent in environmental protection by nitrifying soils and producing hydrogen from solar energy, and to standardize the work in Rhizobials.

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