Team:Michigan/Project

From 2011.igem.org

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(Cell Patterning)
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= '''Cell Patterning''' =
= '''Cell Patterning''' =
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This year’s project explores developing a cell patterning platform based on oligonucleotide-directed cell binding to substrate surfaces. Our approach entails engineering cells to selectively bind to certain nucleotide sequences (via surface display of DNA binding proteins, such as zinc fingers), allowing for guided assembly of defined cell patterns on surfaces patterned with oligonucleotides.
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==Surface Display==
==Surface Display==

Revision as of 19:41, 20 June 2011




Cell Patterning

This year’s project explores developing a cell patterning platform based on oligonucleotide-directed cell binding to substrate surfaces. Our approach entails engineering cells to selectively bind to certain nucleotide sequences (via surface display of DNA binding proteins, such as zinc fingers), allowing for guided assembly of defined cell patterns on surfaces patterned with oligonucleotides.

Surface Display

DNA-Binding Proteins

Microarrays

Results