Team:KULeuven/Modeling

From 2011.igem.org

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<br><p>PARAMETER TABLE
<br><p>PARAMETER TABLE
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<table border="1">
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<tr>
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<th>Header 1</th>
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<th>Header 2</th>
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<tr>
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<td>row 1, cell 1</td>
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<td>row 1, cell 2</td>
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<tr>
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<td>row 2, cell 1</td>
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<td>row 2, cell 2</td>
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</table>
<br><h2>2. Full Model </h2>
<br><h2>2. Full Model </h2>

Revision as of 08:14, 15 September 2011

KULeuven iGEM 2011

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overview     Freeze     Antifreeze     Cell Death

Modeling Overview


1. Describing the whole system

To make predictions for are plasmid transformed E.coli, a structured segregated model is designed in Simbiology. A graphical representation of the model was build in the block diagram editor . Afterwards reaction equations and parameters were added. We designed one model for the whole system and 3 models for 3 subsystems. The 3 subsystems are antifreeze, freeze and cell death. For more information about these 3 subsystems, we refer to the extended project description and the 3 modelling pages.


PARAMETER TABLE

Header 1 Header 2
row 1, cell 1 row 1, cell 2
row 2, cell 1 row 2, cell 2

2. Full Model

There are in total 5 different kinetic equations we used in the model Transcription equation For most promoters, hill kinetics is used, it is a way of quantitatively describing cooperative binding processes, it was developed for hemoglobin in 1913. A Hill coefficient (n) is a measure for the cooperativity. Translation equation RNA degradation Protein degration Assimiliation

3. Simulation tests



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