Team:KULeuven/Discussion

From 2011.igem.org

Revision as of 14:35, 8 June 2011

Instructions

• Login with your iGEM account.

Want to participate in an existing discussion?

• Click on edit next to the concerning discussion.

Want to open a new discussion?

• Click on edit next to the open titles.

How to style the discussion?

• Use this example:
• You can add your signature by clicking on in the button bar at the top of the screen.

Open

Sound/vibration sensor system for E.coli

--Erwinswinnen 09:25, 8 June 2011 (CDT)

--> Jonas:

presence of mechanosensors MscL/MscS in E.coli

use of human hair cells?

--> Koen: Is it recommended to work with E.coli? We can also use human hair cells, then we could make a direct sound sensor in stead of a pressure sensor.

Good websites with the basics of hearing: http://www.ks.uiuc.edu/Research/hearing/ and http://www.beyonddiscovery.org/content/view.page.asp?I=259

In the ear the crucial point is converting the mechanical stimulation of the hair cells into a membrane electric potential which leads to neural signalling. Maybe it is possible to visualize this electic potential and make a correlation between the frequency of the sound and the colour we use. For example a blue colour is generated when the frequency of the sound is X MHz. Another advantage of working with human hair cells is having much more previous research literature. Now we only need the time to explore it ... ;-)

It is impossible to detect sound with only one hair cell (like proposed in my previous mail), of course you need the whole ear organ. However we can still use hair cells for detecting pressure pulses but E. coli is also possible.

    --> Jonas: The advantage of e. coli is that it's easy to work with + the registry is mainly aimed at this bacterium.

Open

Open

Open

Open

Open