Team:Wageningen UR/Project/ModelingProj2
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{{:Team:Wageningen_UR/Templates/Header}} | {{:Team:Wageningen_UR/Templates/Header}} | ||
- | == Fungal Track 'n Trace | + | {{:Team:Wageningen_UR/Templates/NavigationTop1}} |
+ | == Modeling: Fungal Track 'n Trace == | ||
+ | {{:Team:Wageningen_UR/Templates/NavigationLeft3}} | ||
+ | {{:Team:Wageningen_UR/Templates/Style | text= __NOTOC__ | ||
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+ | [[File:Spee_FTnT_Model-1_WUR.jpg|600px|center]] | ||
- | + | The Leu3p (x(2)) dimer blocks transcription from the alpha-IPM synthase (alpha IPMS) promoter. Alpha-IPM (x(1)) binding to this dimer releases it from the promoter and enhances the transcription rate. p(5) and p(6) model both constitutive expression and the transcription rate increase upon alpha-IPM binding. From alpha-IPMS mRNA (x(3)) the protein is formed, modelled by p(9). Alpha-IPMS (x(4)) enzymatically produces alpha-IPM, which is then incorporated in the beginning of this loop again. Intercellular transport of alpha-IPM creates a signal transduction through a hypha. | |
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- | + | Additionally, x(5) is required for modelling the enzymatic reaction. Its formation is described by p(11). Each type of molecule has also been assigned a degradation constant, such as p(8) for x(3). | |
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Latest revision as of 20:20, 21 September 2011