Team:UC Davis

From 2011.igem.org

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<h1>Welcome</h1>
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Welcome to iGEM 2011 at UC Davis!<br><br>
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The four of us have been hard at work on this year's project. We've fine tuned a powerful (and simple) part family generation process, and used it to expand the functionality of the LacI promoter, R0010. We also mutated GFP!<br><br>
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In addition, we developed <a href="https://2011.igem.org/Team:UC_Davis/KO3D">KO3D</a>, an interactive, cross-platform javascript plotting library for displaying scientific data on the web in 3D. <br><br>
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We had a great time at the regional competition in Indianapolis and look forward to seeing all of the other teams at the World Championship at MIT!
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<h1 id=Project>Our Project</h1>
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<p>This is the third time a team at UC Davis has competed in the iGEM Jamboree. This year, we are focusing on foundational advances for <a href="http://biobricks.org/" target="_blank">BioBrick</a> circuit synthesis. Part families, groups of parts with a unified function and differeing characteristics, are some of the most useful parts of the registry. Our project aims to streamline the process of expanding basic parts into part families, from promoters to protein-coding genes.
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<img src="http://farm7.static.flickr.com/6194/6084162068_09cbe08d11_b.jpg" width="250" align="left"></a>We set out to create useful mutant libraries of commonly used parts, starting with the repressible LacI promoter. You can read more about our project<a href="https://2011.igem.org/Team:UC_Davis/Project"> here.</a><br><br>
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We think that thorough characterization should be a priority for all parts submitted to the <a href="http://partsregistry.org" target="_blank">registry</a>. You can view information about our project<a href="https://2011.igem.org/Team:UC_Davis/Project"> here</a>. You can also review our characterization process and <a href="https://2011.igem.org/Team:UC_Davis/Data_LacI">characterization data for LacI</a> on our <a href="https://2011.igem.org/Team:UC_Davis/Data">data</a> page.<br><br>
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<h2>Make Your Own Part Family</h2>
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Our <a href="https://2011.igem.org/Team:UC_Davis/PartFamilies">part family expansion process</a> turns basic parts into part families. Check out how easy it is to improve your favorite BioBricks! You can also listen to Nick and Aaron discuss the process on our <a href="http://www.soundcloud.com/igem-at-uc-davis/part-families-rock">Soundcloud</a> page.
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<h2>Team</h2>
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The <a href="https://2011.igem.org/Team:UC_Davis/Team">team</a> page has information on the four undergrads that make up this year's team, their advisors, as well as contact information for getting in touch with us.<br><br><br>
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<p class="indent"> Welcome to our page!  Our team is comprised of 6 dedicated individuals: 4 undergraduates and 2 advisors. This will be the third year that iGEM @ UC Davis participates in the competition.  We are hard at work and are looking forward towards the completion of our project. Stay tuned for the upcoming results!
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<p class="indent">This summer, we started with the goal of building a novel circuit encoding the function of spatial oscillator that would push the bounds of what had been done before, both scientifically and in the context of device complexity. Our device required the assembly of >30 individual parts and had 7 promoters - both on the very high end of what has been demonstrated in most projects. Clearly, this was ambitious and was going to test how robust the immature technologies we use in synthetic really are. We anticipated challenges and got them in spades. . . One of the most interesting, in which we invested a lot of effort tracking down, was the discovery that the commonly used part BBa_C0051 (the cI lambda phage repressor) could, in the right context have promoter activity. We have spent some time tracking the source of this activity and generated a construct that corrects this error . . .for more, <a href="https://2010.igem.org/Team:UC_Davis/notebook/c0051debug.html">click here!</a>
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<h2>Safety</h2>
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Our <a href="https://2011.igem.org/Team:UC_Davis/Safety">safety</a> page discusses the potential impact of our project on environmental, public, and researcher safety. It also contains our answers to the iGEM 2011 <a href="https://2011.igem.org/Team:UC_Davis/Safety#Questionnaire"> safety questionnaire.</a><br><br>
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<h2>Notebook</h2>
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The <a href="https://2011.igem.org/Team:UC_Davis/Notebook">notebook</a> page contains daily updates about our progress in lab, and also has a <a href="https://2011.igem.org/Team:UC_Davis/Gallery">gallery</a> where you can view pictures that we've taken in our lab.<br><br><br>
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Welcome to the UCD iGEM 2011 page! 
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<h2>Attributions</h2>
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Credit for the various facets of our project, from wetlab work to graphic design can be found on our <a href="https://2011.igem.org/Team:UC_Davis/Attributions">attributions</a> page, along with a list of the awesome, free, open-source software that we used to make this project happen.
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We're currently constructing this site so stay tuned for more info!
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See our notebook page for daily entries.
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Latest revision as of 23:54, 28 October 2011

Our Sponsors

Start a Family

Got a favorite BioBrick? Check our our process for expanding basic parts into part families.

Criteria

View our judging criteria for iGEM 2011 here.

Welcome

Welcome to iGEM 2011 at UC Davis!

The four of us have been hard at work on this year's project. We've fine tuned a powerful (and simple) part family generation process, and used it to expand the functionality of the LacI promoter, R0010. We also mutated GFP!


In addition, we developed KO3D, an interactive, cross-platform javascript plotting library for displaying scientific data on the web in 3D.

We had a great time at the regional competition in Indianapolis and look forward to seeing all of the other teams at the World Championship at MIT!

Our Project

This is the third time a team at UC Davis has competed in the iGEM Jamboree. This year, we are focusing on foundational advances for BioBrick circuit synthesis. Part families, groups of parts with a unified function and differeing characteristics, are some of the most useful parts of the registry. Our project aims to streamline the process of expanding basic parts into part families, from promoters to protein-coding genes. We set out to create useful mutant libraries of commonly used parts, starting with the repressible LacI promoter. You can read more about our project here.

We think that thorough characterization should be a priority for all parts submitted to the registry. You can view information about our project here. You can also review our characterization process and characterization data for LacI on our data page.

Make Your Own Part Family

Our part family expansion process turns basic parts into part families. Check out how easy it is to improve your favorite BioBricks! You can also listen to Nick and Aaron discuss the process on our Soundcloud page.

Team

The team page has information on the four undergrads that make up this year's team, their advisors, as well as contact information for getting in touch with us.


Safety

Our safety page discusses the potential impact of our project on environmental, public, and researcher safety. It also contains our answers to the iGEM 2011 safety questionnaire.

Notebook

The notebook page contains daily updates about our progress in lab, and also has a gallery where you can view pictures that we've taken in our lab.




Attributions

Credit for the various facets of our project, from wetlab work to graphic design can be found on our attributions page, along with a list of the awesome, free, open-source software that we used to make this project happen.

Retrieved from "http://2011.igem.org/Team:UC_Davis"