Team:NYC Software

From 2011.igem.org

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                 <h3>NYC Software Development and Genome Analysis Team</h3>
                 <h3>NYC Software Development and Genome Analysis Team</h3>
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                <h4>Deinococcus Genome / Transcriptome Sequencing</h4>
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                  <h4>Registry/ Biobrick Tools</h4>
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                 To discover genes that may protect against ionizing radiation, we are sequencing the genomes of 20 radiation-resistant Deinococcus species. We are also performing RNA-seq experiments to ascertain what genes are upregulated by radiation exposure.  
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                 Our primary aim is to develop tools to make iGEM easier. We realize that three months is an incredibly short time to attempt ambitious synthetic biology projects, so we are working to code tools that will allow future iGEMers to develop their experimental plans more quickly. Our <a href="http://www.nysynbio.org/cgi/Biobrick_primers.cgi">Primer Designer </a>will take a given sequence and output the primers necessary to biobrick that part. When searching the Registry to see if your parts has been biobricked already, text searches turn out to be an inefficient way to find this information. Instead, perhaps you could use <a href="http://www.nysynbio.org/cgi/BLAST.html">our BLAST Tool</a> to search based on your parts' sequence instead of the arbitrary name humanity has given it.  
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                <h4>Registry/ Biobrick Tools</h4>
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                 We also realize that there are unsolved problems on the software side of synthetic biology, so we are working with others to code tools to integrate into the Registry and are working on libraries to manipulate biobricks in general.  
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            <h4>Deinococcus Genome Sequencing</h4>
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                 Our wetlab partner team's goal is to discover novel responses to radiation resistance in bacteria by cloning a lot of genes and testing them. We aim to aid that effort by sequencing the genomes of species of the radiation-resistant Deinococcus genus and to identify genes that may be responsible for increased protection against superoxide radicals and ionizing radiation. This is a pretty ambitious goal, but thanks to a large donation from Illumina and our location here in the Mason Lab at Weill Cornell we can make it happen.  
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Latest revision as of 19:38, 28 September 2011