"
Team:Peking S
From 2011.igem.org
(Difference between revisions)
| (14 intermediate revisions not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{https://2011.igem.org/Team:Peking_S/bannercss}} | {{https://2011.igem.org/Team:Peking_S/bannercss}} | ||
| - | |||
| - | |||
<HTML> | <HTML> | ||
<head> | <head> | ||
| Line 23: | Line 21: | ||
<div id="backtoigem2011" style="position:absolute; overflow:hidden; left:770px; top:300px; width:200px; height:200px; z-index:23"> | <div id="backtoigem2011" style="position:absolute; overflow:hidden; left:770px; top:300px; width:200px; height:200px; z-index:23"> | ||
| - | <font face="verdana "class="ws14">TO IGEM HQ! | + | <font face="verdana "class="ws14" color="#ffffff">TO IGEM HQ! |
<a href=https://2011.igem.org> | <a href=https://2011.igem.org> | ||
<img src="https://static.igem.org/mediawiki/2011/8/87/Pkus2011igemLOGO.png" alt="" title="" border=0 width=150 height=150> | <img src="https://static.igem.org/mediawiki/2011/8/87/Pkus2011igemLOGO.png" alt="" title="" border=0 width=150 height=150> | ||
| Line 40: | Line 38: | ||
<font color="#FFFF00" face="verdana" ><span style="font-size:21px"><B>S</span><span style="font-size:16px"><font color="#ffffff" class="ws16">ponsed By</B></font></span></div> | <font color="#FFFF00" face="verdana" ><span style="font-size:21px"><B>S</span><span style="font-size:16px"><font color="#ffffff" class="ws16">ponsed By</B></font></span></div> | ||
| - | <div id="text5" style="position:absolute; overflow:hidden; left: | + | <div id="text5" style="position:absolute; overflow:hidden; left:120px; top:750px;width:200px z-index:100;"> |
| - | <font color="#FFFF00" face="verdana" ><span style="font-size:21px"><B>Click </span><span style="font-size:16px"><font color="#000000" class="ws16"> To access a brief introduction of our project<br><br></B></font></span></div> | + | <font color="#FFFF00" face="verdana" ><span style="font-size:21px"><B>Click below</span><span style="font-size:16px"><font color="#000000" class="ws16"> To access a brief introduction of our project<br><br></B></font></span></div> |
| Line 49: | Line 47: | ||
<div id="text2" style="position:absolute; overflow:hidden;left:120px; top:440px; width:700px;z-index:1;"> | <div id="text2" style="position:absolute; overflow:hidden;left:120px; top:440px; width:700px;z-index:1;"> | ||
<font face="verdana " color="#000000"> | <font face="verdana " color="#000000"> | ||
| + | |||
| + | |||
| + | <a href=http://sharesend.com/8nkvq> | ||
| + | <b>Project presentation</b> | ||
| + | <br> | ||
| + | |||
| + | </a> | ||
| + | |||
| + | |||
| + | |||
| + | |||
<b>Cell-cell communication</b>-based multicellular networks provide an extended vista for synthetic biology. However, ‘chemical wires’ that allow versatile concurrent communications are far from sufficient. | <b>Cell-cell communication</b>-based multicellular networks provide an extended vista for synthetic biology. However, ‘chemical wires’ that allow versatile concurrent communications are far from sufficient. | ||
| - | Accordingly, our project intends to develop a versatile ‘chemical wire’ toolbox for both multicellular Boolean computing and non-Boolean dynamics by two approaches. Firstly, a set of recently reported novel quorum sensing systems have been characterized. Secondly, quorum sensing (QS) based transcriptional repression | + | Accordingly, our project intends to develop a versatile ‘chemical wire’ toolbox for both multicellular Boolean computing and non-Boolean dynamics by two approaches. Firstly, a set of recently reported novel quorum sensing systems have been characterized. Secondly, quorum sensing (QS) based transcriptional repression systems have been built from the ground up by conversing LuxR family of transcription activators into repressors. We next sought to develop design rules of microbial consortia as supplements to this toolbox. To validate this toolbox together with the design rules, several robust combinational and sequential logic circuits that are difficult to be implemented in single cell have been constructed as a proof of concept for Boolean logic. As for non-Boolean dynamics, a balancer of microbial population density has been created with supporting microfluid device. |
<br> | <br> | ||
<a href=https://2011.igem.org/Team:Peking_S/project> | <a href=https://2011.igem.org/Team:Peking_S/project> | ||
| Line 56: | Line 65: | ||
</a> | </a> | ||
| + | |||
</div> | </div> | ||
| Line 61: | Line 71: | ||
<object classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=7,0,19,0" width="850" height="370" align="middle" > | <object classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=7,0,19,0" width="850" height="370" align="middle" > | ||
| - | <param name="movie" value="https://static.igem.org/mediawiki/2011/ | + | <param name="movie" value="https://static.igem.org/mediawiki/2011/6/66/PkuModule2.swf" /> |
<param name="quality" value="high" /> | <param name="quality" value="high" /> | ||
<param name="wmode" value="transparent"> | <param name="wmode" value="transparent"> | ||
| - | <embed src="https://static.igem.org/mediawiki/2011/ | + | <embed src="https://static.igem.org/mediawiki/2011/6/66/PkuModule2.swf" quality="high" wmode="transparent" pluginspage="http://www.macromedia.com/go/getflashplayer" type="application/x-shockwave-flash" width="860" height="370"></embed> |
</object> | </object> | ||
</div> | </div> | ||
| Line 71: | Line 81: | ||
<img src="https://static.igem.org/mediawiki/igem.org/d/d9/PkusSubtitleshort.png" width="320"> | <img src="https://static.igem.org/mediawiki/igem.org/d/d9/PkusSubtitleshort.png" width="320"> | ||
</div> | </div> | ||
| - | <div id="image1" style="position:absolute; overflow:hidden; left:489px; top:1134px; width:292px; height:37px; z-index:40"><a href="http://www. | + | <div id="image1" style="position:absolute; overflow:hidden; left:489px; top:1134px; width:292px; height:37px; z-index:40"><a href="http://www.phy.pku.edu.cn/English.html"><img src="https://static.igem.org/mediawiki/2011/7/7e/Pkuphy1.png" alt="" title="" border=0 width=292 height=37></div> |
<div id="image2" style="position:absolute; overflow:hidden; left:501px; top:1230px; width:294px; height:36px; z-index:41"><a href="http://ctb.pku.edu.cn/main/en/index.htm"><img src="https://static.igem.org/mediawiki/2011/8/8e/PekingR_PKU_CTB.gif" alt="" title="" border=0 width=294 height=36></div> | <div id="image2" style="position:absolute; overflow:hidden; left:501px; top:1230px; width:294px; height:36px; z-index:41"><a href="http://ctb.pku.edu.cn/main/en/index.htm"><img src="https://static.igem.org/mediawiki/2011/8/8e/PekingR_PKU_CTB.gif" alt="" title="" border=0 width=294 height=36></div> | ||
| Line 92: | Line 102: | ||
__NOTOC__ | __NOTOC__ | ||
{{https://2011.igem.org/Team:Peking_S/tagcloud}} | {{https://2011.igem.org/Team:Peking_S/tagcloud}} | ||
| + | {{https://2011.igem.org/Team:Peking_S/bareback}} | ||
Latest revision as of 05:31, 23 October 2011
Template:Https://2011.igem.org/Team:Peking S/bannercss
TO IGEM HQ!
A ‘Chemical Wire’ Toolbox for Synthetic Microbial Consortia
Quick Links
Sponsed By
Click below To access a brief introduction of our project
Project presentation
Cell-cell communication-based multicellular networks provide an extended vista for synthetic biology. However, ‘chemical wires’ that allow versatile concurrent communications are far from sufficient. Accordingly, our project intends to develop a versatile ‘chemical wire’ toolbox for both multicellular Boolean computing and non-Boolean dynamics by two approaches. Firstly, a set of recently reported novel quorum sensing systems have been characterized. Secondly, quorum sensing (QS) based transcriptional repression systems have been built from the ground up by conversing LuxR family of transcription activators into repressors. We next sought to develop design rules of microbial consortia as supplements to this toolbox. To validate this toolbox together with the design rules, several robust combinational and sequential logic circuits that are difficult to be implemented in single cell have been constructed as a proof of concept for Boolean logic. As for non-Boolean dynamics, a balancer of microbial population density has been created with supporting microfluid device.
learn more
Cell-cell communication-based multicellular networks provide an extended vista for synthetic biology. However, ‘chemical wires’ that allow versatile concurrent communications are far from sufficient. Accordingly, our project intends to develop a versatile ‘chemical wire’ toolbox for both multicellular Boolean computing and non-Boolean dynamics by two approaches. Firstly, a set of recently reported novel quorum sensing systems have been characterized. Secondly, quorum sensing (QS) based transcriptional repression systems have been built from the ground up by conversing LuxR family of transcription activators into repressors. We next sought to develop design rules of microbial consortia as supplements to this toolbox. To validate this toolbox together with the design rules, several robust combinational and sequential logic circuits that are difficult to be implemented in single cell have been constructed as a proof of concept for Boolean logic. As for non-Boolean dynamics, a balancer of microbial population density has been created with supporting microfluid device.
learn more
Template:Https://2011.igem.org/Team:Peking S/tagcloud Template:Https://2011.igem.org/Team:Peking S/bareback
