Team:GeorgiaTech/Abstract

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<center><b>Title:</b> De Novo Adaptation of Streptococcus thermophilus CRISPR1 Defense in E. coli</center>
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The ultimate goal of our project was to utilize this system as a mobile gene targeting system capable of eliminating antibiotic resistance. The protoype construct, pSTINGER, was designed for quantitative modeling, proof of concept, and vaccination on a single plasmid. As a result of experimental error, intellectual property agreements, material availability, our biobrick constructs remain experimentally theoretical, though we have rigorously modeled our system in various scenarios.
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Latest revision as of 03:44, 29 September 2011

Title: De Novo Adaptation of Streptococcus thermophilus CRISPR1 Defense in E. coli


Abstract:

The ultimate goal of our project was to utilize this system as a mobile gene targeting system capable of eliminating antibiotic resistance. The protoype construct, pSTINGER, was designed for quantitative modeling, proof of concept, and vaccination on a single plasmid. As a result of experimental error, intellectual property agreements, material availability, our biobrick constructs remain experimentally theoretical, though we have rigorously modeled our system in various scenarios.