Team:Wageningen UR/Safety/Nine

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Building a Synchronized Oscillatory System

Biosafety and biosecurity considerations

Does your country have national biosafety regulations or guidelines?

In the Netherlands, any person or institution intending to perform genetic modifications needs to have licenses of the Royal Order on Genetic Modified Organisms (which is called ‘Besluit GGO’ in Dutch), Regulation Genetic Modified Organisms (‘Regeling GGO’) and environmental legislation as the Law on Environmental Management (‘Wet Milieubeheer’). These laws are directed too by the Dutch governmental page on Biotechnology laws. Food related genetic modifications and border crossing transport of genetic modified (micro-)organisms are also regulated by European legislation. While neither one of these is valid for our project this will not be extracted further on this page, but more information could be found on the site of the European Biosafety Clearing-House.

The Royal Order on Genetic Modified Organisms is for the greater part about the classification of the organisms, in which consideration is taken about possible modifications of their genomes. Our team has applied this information by rejecting any project idea that requested a cell chassis of BSL 2 and higher from the list with brainstorm ideas we made.

According to the Regulation Genetic Modified Organisms Wageningen UR holds a number of (biological) safety workers. Every lab has a laboratory manager, or practical tutor. This person has introduced every team member to the lab by giving them a “safety tour.” Therein, we came across all the rules and information we should regard about: discarding biological and chemical waste, disinfection of the lab bench, what to wear in the lab, how to act in case of an emergency and more. The laboratory manager sees to it that genetic modification related research is being executed according to the involved rules. If an accident happens, like aerosol formation, the manager also is the first person who would be notified about this. Next to our project also, possible more risk full, lab work can be performed by others, so the practical tutor’s instruction, supervision and presence are welcome.

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-== Safety ==
+== Biosafety and biosecurity considerations ==
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-=== References ===
+=== Does your country have national biosafety regulations or guidelines? ===
-Kim M, Shin JH, Suh SP, Ryang DW, Park CS, Kim C, Kook H, Kim J.   '''Aspergillus nidulans infection in a patient with chronic granulomatous disease'''.   J Korean Med Sci. 1997 Jun;12(3):244-248. <br />URL: http://synapse.koreamed.org/DOIx.php?id=10.3346%2Fjkms.1997.12.3.244. <br />A small fragment was used. Copyright © 1997 The Korean Academy of Medical Sciences.
+In the Netherlands, any person or institution intending to perform genetic modifications needs to have licenses of the Royal Order on Genetic Modified Organisms (which is called ‘Besluit GGO’ in Dutch), Regulation Genetic Modified Organisms (‘Regeling GGO’) and environmental legislation as the Law on Environmental Management (‘Wet Milieubeheer’). These laws are directed too by the Dutch governmental page on [[http://www.rijksoverheid.nl/onderwerpen/biotechnologie/wetten-en-regels-biotechnologie|Biotechnology laws]]. Food related genetic modifications and border crossing transport of genetic modified (micro-)organisms are also regulated by European legislation. While neither one of these is valid for our project this will not be extracted further on this page, but more information could be found on the site of the European [[http://bch.cbd.int/| Biosafety Clearing-House]].
-<br />[https://2011.igem.org/Team:Wageningen_UR/Safety/One Return to Pathogenicity of host organisms]
+The Royal Order on Genetic Modified Organisms is for the greater part about the classification of the organisms, in which consideration is taken about possible modifications of their genomes. Our team has applied this information by rejecting any project idea that requested a cell chassis of BSL 2 and higher from the list with brainstorm ideas we made.
-EPA(U.S. Environmental Protection Agency). (2011, January Monday). Escherichia coli K-12 TSCA Section 5(h)(4) Exemption: Final Decision Document. Retrieved July 2011, from Biotechnology Program under the Toxic Substances Control Act (TSCA):
+According to the Regulation Genetic Modified Organisms Wageningen UR holds a number of (biological) safety workers. Every lab has a laboratory manager, or practical tutor. This person has introduced every team member to the lab by giving them a “safety tour.” Therein, we came across all the rules and information we should regard about: discarding biological and chemical waste, disinfection of the lab bench, what to wear in the lab, how to act in case of an emergency and more. The laboratory manager sees to it that genetic modification related research is being executed according to the involved rules. If an accident happens, like aerosol formation, the manager also is the first person who would be notified about this. Next to our project also, possible more risk full, lab work can be performed by others, so the practical tutor’s instruction, supervision and presence are welcome.
-<br />http://www.epa.gov/biotech_rule/pubs/fra/fd004.htm
-<br />[https://2011.igem.org/Team:Wageningen_UR/Safety/One Return to Pathogenicity of host organisms]
-iGEM. (2011). Safety. Retrieved July 2011, from iGEM 2011:
-<br />https://2011.igem.org/Safety
-<br />[https://2011.igem.org/Team:Wageningen_UR/Safety/Six Return to Notification]
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