Team:USTC-Software/human practice

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          <p style="font-size:large; color:#F00"> Safety </p>
 
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          <hr/>
 
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          <p>Synthetic Biology is a revolutionary field which combines several disciplines such as biology, chemistry, mathematics, physics
 
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          and engineering. However, it may cause intentional or accidental harm to humans, agriculture or the environment. </p>
 
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          <p>As a software project our work does not raise many safety issues typically associated with biological wet-lab project. Nevertheless we
 
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          will explicitly present the answer to the four safety questions here:</p>
 
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          <p>1.Q: Would any of your project ideas raise safety issues in terms of:
 
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          <ul type="square"> <li>researcher safety,</li> <li>public safety, or</li> <li>environmental safety?</li> </ul>
 
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          A:<ol type="i">
 
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          <li>Safety for researchers<br/>
 
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          The development of software requires many hours` work in front of a computer, which is not ergonomic to programmers, as working
 
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          in such environment may cause much exhaust and stress. Therefore, we made a series of rules to guarantee that we can take regular
 
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          breaks. Furthermore, every time our programmers go to wet labs, to work with our wet team members, we make sure that they are
 
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          properly equipped and supervised by a well-trained staff.</li>
 
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          <li> Safety for public<br/>
 
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          <i>Lachesis</i>, is ONLY for research use, no medical or diagnostic use for applications of novel BioBrick constructs
 
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          generated through our software, and no military (defense or combat) application will be allowed.</li>
 
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          <li>Safety for environment<br/>
 
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          We do not perform any work that put the environment at any risk. </li>
 
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          </ol>
 
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          </p>
 
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          <p>2.Q: Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues? If yes,
 
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            <ul type="square"> <li>did you document these issues in the Registry?</li>
 
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            <li>how did you manage to handle the safety issue?</li>
 
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            <li>how could other teams learn from your experience?</li>
 
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          A: <i>Lachesis</i>, does not create any new BioBrick parts (or devices) in reality, and the BioBricks we
 
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          used are only encoding non-hazardous genes. No safety issues would arouse as a result.
 
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          </p>
 
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          <p> 3.Q: Is there a local biosafety group, committee, or review board at your institution?<br/>
 
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          <ul type="square"> <li> If yes, what does your local biosafety group think about your project?</li>
 
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              <li> If no, which specific biosafety rules or guidelines do you have to consider in your country?</li> </ul>
 
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          A:Yes. School of Life Sciences, University of Science and Technology of China is aware of
 
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          our project and we are working under the instruction of our instructors.
 
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          (<i> <a href="http://synbio.ustc.edu.cn/hongjiong.html" target="_blank">Pro.Jiong Hong </a> </i>,
 
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          associate professor of <a href="http://synbio.ustc.edu.cn" target="_blank">synthetic biology lab</a>
 
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          in <abbr title="University of Science and Technology of China"> USTC</abbr>. <i>Zhaofeng Luo,</i> director
 
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          of protein research instruments group in <abbr title="University of Science and Technology of China"> USTC</abbr>.
 
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          <i> <a href="http://home.ustc.edu.cn/~feicaiyi/people.html" target="_blank">Pro.Haiyan Liu</a> </i>,
 
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          professor of <a href="http://home.ustc.edu.cn/~feicaiyi/index.html" target="_blank">computational biology </a>
 
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          in <abbr title="University of Science and Technology of China"> USTC</abbr>.)<br/>
 
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          The safety guidelines could be obeyed sufficiently in our working environment during the project.<br/>
 
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          </p>
 
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          <p>4. Do you have any other ideas how to deal with safety issues that
 
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          could be useful for future <abbr title ="International Genetically Engineered Machine">iGEM </abbr> competitions?
 
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          How could parts, devices and systems be made even safer through biosafety engineering?</strong><br/>
 
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          <a href="http://www.who.int/topics/biosafety/en/" target="_blank" style="float:right">
 
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          A:<ol type="i">
 
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          <li>Yes, A lot of work is expected to be completed in dry lab for the safety issues,
 
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          besides what have been finished now. For example, safety issues for intellectual property should be taken into consideration.
 
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          Thus we suggest that all source codes and documentation should be granted with copyrights before sharing.</li>
 
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          <li>With more detailed and better characterized parts, synthetic biology can be an extremely controlled and safe experience.
 
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          Benefit from this, we would be one step closer in integrating with the environment.</li>
 
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   Welcome to &#160;&#160;<a href="http://en.ustc.edu.cn/" target="_blank">University of Science and Technology of China</a>&#160;!
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Team:USTC-Software - 2011.igem.org/human practice

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