Team:Grenoble/Projet/Results

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<div  class="blocbackground" id="Achievements">
<div  class="blocbackground" id="Achievements">
    <h1>Achievements</h1>
    <h1>Achievements</h1>
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On this page you can find the achievements of our project.
 
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In each part, we tried to speak about both experiment and modelling, in order to validate our model and optimized  
In each part, we tried to speak about both experiment and modelling, in order to validate our model and optimized  
by simulation the device.<br/><br/>
by simulation the device.<br/><br/>
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  <a href="http://2011..org/Team:Grenoble/Projet/Results/Toggle" ><img class="icon" src="http://2011..org/wiki/images/2/20/Bouton_toggle.png"/></a>
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  <a href="https://2011.igem.org/Team:Grenoble/Projet/Results/Toggle" ><img class="icon" src="https://static.igem.org/mediawiki/2011/2/20/Bouton_toggle.png"/></a>
     
     
      <big><big><a href="https://2011.igem.org/Team:Grenoble/Projet/Results/Toggle" class="menu">Validation of the network</a></big></big><br/>
      <big><big><a href="https://2011.igem.org/Team:Grenoble/Projet/Results/Toggle" class="menu">Validation of the network</a></big></big><br/>

Latest revision as of 03:20, 29 October 2011

Grenoble 2011, Mercuro-Coli iGEM


Achievements

Table of content

We describe here the modeling and experimental results obtained for each network module, in order to validate our model and optimize the device: the toggle switch, the quorum sensing and the translational regulation system RsmA.

  1. Validation of the genetic network
  2. The essential role of rmsA regulation system
  3. Device optimization and specifications
In each part, we tried to speak about both experiment and modelling, in order to validate our model and optimized by simulation the device.

Validation of the network
Toggle Switch and Quorum sensing behavior
Validation of the model
Dynamic study of the stability


The essential role of rsmA regulation system
Why do we need this system ?
Leader sequence characterization
rsmA characterization


Device specificities and optimization
Optimization of the device
Determination of the limit of quantification
Stochastic study for statistic determination of several device specificities


Sensitivity to parameters study
Robustness of our system
Applicable to mercury



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