Team:IIT Madras

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Google Insights suggests the most number of searches for “synthetic biology” is from India.<br/><br/>
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Yo! Veni, Vidi, Veci!<br/><br/>
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So what do we have in store for iGEM this year?<br/>
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Most research and development of concepts to date has dealt with gene networks. These networks are said to be synthetic because they are novel and designed by humans, never seen in nature. This is analogous to building electronic circuits from individual components. <br/>Recent research has however shown success in developing novel proteins and enzymes which have been designed based on the modularity of proteins. We plan to use the same principle to design an expression system that can be modified on the protein level so that it can be activated by a molecule of our choice. We want to design a novel signal transduction pathway, where the surface receptor can be modified by simply replacing the extracellular sensory domain alone, with little no change in the output pattern. This could be analogous to development of novel electronic components with novel functions. <br/><br/>
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We plan to target this problem by accessing the modularity found in the proteins involved in the two-component signalling pathways of prokaryotes. There are over 250 different pathways that have already been studied to a very large extent and thousands of proteins have been characterized wrt their domain architecture and their functionality.<br/>
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Of the many signalling pathways that have been studied, the EnvZ/OmpR Two component system of ''E.Coli'' is one of the first few to be understood. It is found to be representative of the basic domain architecture found in many of the Two Component systems. <br/>
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Watch this space for more updates…
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<a href="http://www.iitm.ac.in"><img src="https://static.igem.org/mediawiki/2011/a/ab/IIT_Madras_Logo.png" width="100px" height="100px;" style="position:relative; top:-60px; left:-10px;" align="right"/></a>
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<!--<div id="block1" align="left"></div>-->
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<div id="block2" ><div style="width:80%; position:relative; top:30px;">Proteorhodopsin: A Light-Driven Proton Pump</div></div>
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<div id="block3" align="right"><div style="width:80%; position:relative; top:5px;left:-54px">K572001<br/>K572005<br/>K572009<br/>K572100<br/>K572200</div></div>
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<div id="block4" align="right"><div style="width:80%; position:relative; top:15px; left:-33px">Notebook, Data & Protocols</div></div>
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<div id="block5" align="left"><div style="width:80%; position:relative; top:22px; left:83px">In-Silico Simulation</div></div>
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<div id="block6" align="left"><div style="width:80%; position:relative; top:18px; left:10px">A Team of Undergraduates from IIT Madras</div></div>
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<div id="block7" align="left"><div style="width:80%; position:relative; top:90px; left:11px;">Safety Protocols</div></div>
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<div id="block8" align="left"><div style="width:75%; position:relative; top:10px; left:11px;">Spreading the word about a Safer Alternative</div></div>
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<div id="block9" align="left"><div style="width:80%; position:relative; top:10px; left:11px;">Giving due credit</div></div>
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</div>
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<p class="title" id="overview" style="position:absolute; top:120px;left:360px;">Overview</p>
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<p class="title" id="project" style="position:absolute; top:90px;left:530px;">Project</p>
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<p class="title" id="parts" style="position:absolute; top:140px;left:610px;">Parts</p>
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<p class="title" id="about_us" style="position:absolute; top:400px;left:480px;">About Us</p>
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<p class="title" id="safety"  style="position:absolute; top:342px;left:360px;">Safety</p>
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<p class="title" id="human" style="position:absolute; top:280px;left:270px;">Human Practices</p>
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<p class="title" id="attributions" style="position:absolute; top:190px;left:300px;">Attributions</p>
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Our Sponsors :
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<div id="instructions" style="position:relative; top:0px; left:295px; color:#777; width:438px; font-size:14px;"><i><fontsize=7>(Hover over parts to know more. Click on a part to visit its page)</font></i></div>
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<br/><br/>
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<h2><a href="https://2011.igem.org/Team:IIT_Madras/Sponsors">Sponsors:</a></h2>
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<a href="http://alumni.iitm.ac.in/iitmact.php"><img src="https://static.igem.org/mediawiki/2011/8/89/Oaa.jpg"/></a>
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<a href="http://www.madrascements.com/Group%20Website/Groupbase.htm"><img src="https://static.igem.org/mediawiki/2011/d/d3/Flag_Green.jpg" length="120" width="120" style="position:relative;right:-35px"/></a>
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Latest revision as of 03:12, 29 October 2011

bar

Proteorhodopsin: A Light-Driven Proton Pump
K572001
K572005
K572009
K572100
K572200
Notebook, Data & Protocols
In-Silico Simulation
A Team of Undergraduates from IIT Madras
Safety Protocols
Spreading the word about a Safer Alternative
Giving due credit

Overview

Project

Parts

Scribbles

Dry Lab

About Us

Safety

Human Practices

Attributions

(Hover over parts to know more. Click on a part to visit its page)


Sponsors:

Retrieved from "http://2011.igem.org/Team:IIT_Madras"