Team:Grenoble

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<a href="https://2011.igem.org/Team:Grenoble/Projet/Intro" title="Introduction"><img src="https://static.igem.org/mediawiki/2011/d/d3/Slide_home2.png"></img></a>
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<a href="https://2011.igem.org/Team:Grenoble/Projet/regulation" title="RsmA: post-transcriptional regulation system"><img src="https://static.igem.org/mediawiki/2011/1/1a/Slide_home4.png"/></a>
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<h2>Ready for take-off !<span>By the Team</span></h2>
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<p>We are proud to say we obtained our pass for the iGEM World Championship at the MIT (Boston) and got a gold medal !
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We will double our efforts to acomplish our goals until Boston in early November. Many thanks to all our
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<h2>You are welcome !<span>By JB</span></h2>
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<h2>Mercuro-Coli: A new way to quantify heavy metals.<span>By JB</span></h2>
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<h2>Mercuro-Coli: A new way to quantify heavy metals.</h2>
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Welcome on version 0.3 of our wiki ! You may still find some blank pages but we are filling it day by day. Follow the state of our work in the <a href="/Team:Grenoble/Notebook/July">Notebook</a> or learn everything you always wanted to know about Grenoble and tartiflette <a href="/Team:Grenoble/Grenoble" >here !</a>
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Our project aims at constructing an easy to use, transportable sensor capable of quantifying the concentration of mercury, in an aqueous sample.
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Our system is based on a comparison between an unknown mercury concentration and a known IPTG concentration. A linear IPTG gradient is present on a test-strip containing the engineered bacteria. When the mercury solution is added, the regulatory network will switch to one of two states depending on the IPTG/mercury ratio.
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Bacteria become either “sender” or “receiver”. The bacteria sensing a predominance of mercury over IPTG, the “senders”, will release a quorum sensing molecule which is detected by the nearby “receivers”. The reception of quorum sensing molecules will induce the expression of a red dye in the “receivers”. In this way, a red line emerges at a position in the IPTG gradient from which the unknown mercury concentration can be deduced.
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<a href="http://syntheticbiology.org/">
<a href="http://syntheticbiology.org/">
<h2 class="lien"id="Paragraphe2">iGEM and the future of synthetic biology<span>By Geoffrey</span></h2>
<h2 class="lien"id="Paragraphe2">iGEM and the future of synthetic biology<span>By Geoffrey</span></h2>
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<h2> A great human adventure </h2>
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<h2 class="lien"id="Paragraphe2">A great human adventure<span>By Félix</span></h2>
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Now that we have found an interesting  project which seems ethic, and can be useful for the society, we are on the way for 4 month of intense work ! Our group is made of 12 people with very different education , that have to understand and synchronise each other. Since we are spread out in multiple places, we already meet once a week in order to coordinate or work. This need of an efficient communication within the team is an exiting part of the project !  
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Now that we have found an interesting  project and can be useful for the society, we are on the way for 4 month of intense work ! Our group is made of 12 people with very different education , that have to understand and synchronise each other. Since we are spread out in multiple places, we already meet once a week in order to coordinate or work. This need of an efficient communication within the team is an exiting part of the project !  
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Latest revision as of 22:11, 28 October 2011

Grenoble 2011, Mercuro-Coli iGEM

Mercuro-Coli: A new way to quantify heavy metals.

Our project aims at constructing an easy to use, transportable sensor capable of quantifying the concentration of mercury, in an aqueous sample.

Our system is based on a comparison between an unknown mercury concentration and a known IPTG concentration. A linear IPTG gradient is present on a test-strip containing the engineered bacteria. When the mercury solution is added, the regulatory network will switch to one of two states depending on the IPTG/mercury ratio.

Bacteria become either “sender” or “receiver”. The bacteria sensing a predominance of mercury over IPTG, the “senders”, will release a quorum sensing molecule which is detected by the nearby “receivers”. The reception of quorum sensing molecules will induce the expression of a red dye in the “receivers”. In this way, a red line emerges at a position in the IPTG gradient from which the unknown mercury concentration can be deduced.

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