Team:NYMU-Taipei
From 2011.igem.org
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<font size=6><font color=red>'''Tailoring Your Avatar'''</font><br> | <font size=6><font color=red>'''Tailoring Your Avatar'''</font><br> | ||
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To achieve this goal, we use a species of magnetic bacteria,'' Magnetospirillum magneticum'' AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: ''MinC'', a division inhibitor, ''INV'', a gene for invasion and ''LLO'', a gene for facilitated escape from phagosomes.</font> | To achieve this goal, we use a species of magnetic bacteria,'' Magnetospirillum magneticum'' AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: ''MinC'', a division inhibitor, ''INV'', a gene for invasion and ''LLO'', a gene for facilitated escape from phagosomes.</font> | ||
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*'''<font size=3>Our design is made up of the following two devices:</font>'''<br> | *'''<font size=3>Our design is made up of the following two devices:</font>'''<br> |
Revision as of 19:23, 28 October 2011
Tailoring Your Avatar
Create wireless neuro-stimulator, focusing on achieving remote neuro-stimulation to minimize the invasion and damage to the neuron
Optogenetics, the latest neuroscientific method, has improved specificity for stimulating certain cell types of neurons, reversible bi-directional stimulation, and elevated spatiotemporal precision. However, to achieve neuronal network stimulation, light cables are still needed, leaving long-standing annoying issues regarding immune responses unresolved.
To achieve this goal, we use a species of magnetic bacteria, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: MinC, a division inhibitor, INV, a gene for invasion and LLO, a gene for facilitated escape from phagosomes.
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