Team:NYMU-Taipei/Our institute

From 2011.igem.org

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*'''<font size=3>Our design</font>'''<br>
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To achieve this goal, we use a species of magnetic bacteria,'' Magnetospirillum magneticum'' AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: ''MinC'', a division inhibitor, ''INV'', a gene for invasion and ''LLO'', a gene for facilitated escape from phagosomes.</font>
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*'''<font size=3>Our design is made up of the following two devices:</font>'''<br>
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*[https://2011.igem.org/Team:NYMU-Taipei/optomagnetic-design Optomagnetic Design]
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**Bridge magnetics and optogenetics
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*[https://2011.igem.org/Team:NYMU-Taipei/immunological-solution NeuroSymbiosis]
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**Make magnetic bacteria symbiosis with glia cell
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*'''<font size=3>Achievements</font>'''
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<center>[[image:Achievement.png|900px|]]</center>
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Optogenetics, the latest neuroscientific method, has improved specificity for stimulating certain cell types of neurons, reversible bi-directional stimulation, and elevated spatiotemporal precision. However, to achieve neuronal network stimulation, light cables are still needed, leaving long-standing annoying issues regarding immune responses unresolved. This year NYMU-Taipei iGEM team creates wireless neuro-stimulator, focusing on achieving remote neuro-stimulation to minimize the invasion and damage to the neuron. To achieve this goal, we use a species of magnetic bacteria, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: ''MinC'', a division inhibitor, ''INV'', a gene for invasion and ''LLO'', a gene for facilitated escape from phagosomes. Overall, our project will make optogenetic neuro-stimulation wireless and safe.</font>
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*'''<font size=3>Our institute</font>'''
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*<font size=2>The official web pages of our school - National Yang Ming University (NYMU):
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** [http://web.ym.edu.tw/front/bin/home.phtml in Chinese]
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** [http://nymu-e.web.ym.edu.tw/front/bin/home.phtml in English]
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* Follow the two links below to see <font color="red">'''The Beauty of NYMU'''</font>
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** [http://issue.ym.edu.tw/cia/new/ Take a panoramic scenery view of our university]
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** [http://issue.ym.edu.tw/cia/new/tw/ym720.html Take a tour of our university]
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Latest revision as of 19:17, 28 October 2011

  • Our design

To achieve this goal, we use a species of magnetic bacteria, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we choose three genes to achieve symbiosis within glial cell: MinC, a division inhibitor, INV, a gene for invasion and LLO, a gene for facilitated escape from phagosomes.


  • Our design is made up of the following two devices:

  • Achievements

Achievement.png

  • Our institute
  • The official web pages of our school - National Yang Ming University (NYMU):
    • [http://web.ym.edu.tw/front/bin/home.phtml in Chinese]
    • [http://nymu-e.web.ym.edu.tw/front/bin/home.phtml in English]
  • Follow the two links below to see The Beauty of NYMU
    • [http://issue.ym.edu.tw/cia/new/ Take a panoramic scenery view of our university]
    • [http://issue.ym.edu.tw/cia/new/tw/ym720.html Take a tour of our university]

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