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- | </html><html><div align="center"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan" border="0"><img src="https://static.igem.org/mediawiki/2011/5/5e/Tokyo_Metropolitan_Header.png"></a><br>
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- | <table border="0" cellpadding=0 cellspacing=0>
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- | <td width="94" border="0"><div class="rollover01"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan" border="0"><img src="http://igemtmu.net/2011/wiki/home.png"></div></a></td>
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- | <td width="88"><div class="rollover02"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan/Team" border="0"><img src="http://igemtmu.net/2011/wiki/team.png"></div></a></td>
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- | <td width="108"><div class="rollover03"><a href="https://igem.org/Team.cgi?year=2011&team_name=Tokyo_Metropolitan" border="0"><img src="http://igemtmu.net/2011/wiki/profile.png"></div></a></td>
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- | <td width="123"><div class="rollover04"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan/Project" border="0"><img src="http://igemtmu.net/2011/wiki/project.png"></div></a></td>
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- | <td width="83"><div class="rollover05"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan/Parts" border="0"><img src="http://igemtmu.net/2011/wiki/parts.png"></div></a></td>
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- | <td width="163"><div class="rollover06"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan/Notebook" border="0"><img src="http://igemtmu.net/2011/wiki/notebook.png"></div></a></td>
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- | <td width="118"><div class="rollover07"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan/Safety" border="0"><img src="http://igemtmu.net/2011/wiki/safety.png"></div></a></td>
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- | <td width="198"><div class="rollover08"><a href="https://2011.igem.org/Team:Tokyo_Metropolitan/Attributions" border="0"><img src="http://igemtmu.net/2011/wiki/attributions.png"></div></a></td>
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- | <font size="4"><b>Our project : BeE.coli</b></font><br><br>
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- | We propose the project "BeE.coli" as a micro injection system. <br>
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- | BeE.coli has the abilities to move fast and target pathogens concentrated area. <br>
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- | Getting close to pathogens, it sends the killer gene to them with conjugation. Then pathogens will be killed.<br>
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- | To accomplish this project, we planned to add three functions to E.coli.<br>
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- | First, expression of the mutant H-NS proteins enables E.coli to move faster. This contributes to increasing the frequency of conjugation.<br>
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- | Second function is new taxis for AHL. We make the target bacteria as a model of pathogens, and they produce AHL. BeE.coli goes for the area where high concentrations of AHL that means concentration of target bacteria. <br>
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- | Last, BeE.coli kills pathogens by sending the killer gene with the conjugative plasmid. BeE.coli has the anti killer gene repressing the killer gene.<br>
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- | In the future, BeE.coli will be useful for medical scenes.<br>
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- | </div>
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- | <td width="250">
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- | <img src="http://igemtmu.net/2011/wiki/bandh.png" width="250">
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- | </td>
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- | </tr>
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- | </table>
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- | <img src="http://igemtmu.net/2011/wiki/speedup.png" width="200">
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- | <img src="http://igemtmu.net/2011/wiki/targeting.png" width="200">
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- | <img src="http://igemtmu.net/2011/wiki/killing.png" width="200">
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- | <img src="http://igemtmu.net/2011/wiki/visualization.png" width="200">
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- | </div></html>
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