Team:Virginia/Resources

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                     <li><a href="https://2011.igem.org/Team:Virginia/Parts" >PARTS</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/Parts" >PARTS</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/Modeling" >MODELING</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/Modeling" >MODELING</a></li>
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                    <li><a href="http://openwetware.org/wiki/IGEM:Virginia/2009/Notebook/VGEM2011/2011" target="_blank">NOTEBOOK</a></li>
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<li><a href="https://2011.igem.org/Team:Virginia/Notebook">NOTEBOOK</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/Safety" >SAFETY</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/Safety" >SAFETY</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/HumanPractices" >HUMAN PRACTICES</a></li>
                     <li><a href="https://2011.igem.org/Team:Virginia/HumanPractices" >HUMAN PRACTICES</a></li>
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     <h1>Resources</h1>
     <h1>Resources</h1>
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    <h2>Software Tools</h2>
 
     <h2>Advice and Best Practices for Future iGEM Teams</h2>
     <h2>Advice and Best Practices for Future iGEM Teams</h2>
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<p>Original research rarely goes according to plan. Many of your experiments will fail. Prepare for this by splitting your project into phases that can be completed in parallel.</p>
 +
<p>Be very careful when ordering DNA synthesized by a third party. Especially be ware that by default you will be shipped single-stranded DNA, so you must specify "duplex" if you need double-stranded DNA.</p>
 +
<p>Collaborate with other students from different disciplines. Their perspectives will challenge you to think in new ways about the problems at hand.</p>
 +
<p>Take initiative, be willing to take responsibilities, and get active in seeking out and learning new techniques.</p>
 +
<p>Be curious about a field you have not explored before entering the research group.</p>
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     <h1>External Links</h1>
     <h1>External Links</h1>
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    <p>
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<h2>Tools</h2>
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    Synthetic biology and biomedical research raise many complex legal, ethical, and pragmatic issues related to how intellectual property law and practice influence innovation, impact technology, and ultimately alter society. After a review of relevant literature and our own experiences, we conclude that the current intellectual property-centric approach to innovation management has become destructive of its intentions, hampering innovation and systematically limiting access.
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    </p>
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<p><a href="http://arep.med.harvard.edu/labgc/adnan/projects/Utilities/revcomp.html" target="_blank">Reverse and/or Complimentary Sequences</a> - Free, browser-based applet for manipulating sequences according to IUPAC conventions</p>
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    <p>
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Given the rapid emergence of uniquely challenging new fields like synthetic biology that bear enormously on the public good, our innovation management process urgently demands fundamental renegotiation. Within our legal framework, there should at minimum be several new infringement exemptions, more careful distinctions between the patentability of completely novel and naturally derived “innovations,” and stronger limitations on the ability of patent-holders to exclude others from exploiting a technology when they are not adequately developing the technology themselves, among other reforms, and the entire intellectual property regime should eventually be replaced with a reward system. Further, independent organizations like Openwetware and the Biobrick Foundation can do more to improve their impact on synthetic biology while serving as a laboratory of innovation for testing new methods of promoting innovation that can be generalized to other fields.
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<p><a href="http://serialbasics.free.fr/Serial_Cloner.html" target="_blank">Serial Cloner 2.1</a> - Free, light molecular biology utility</p>
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<p><a href="http://www.dna20.com/genedesigner2/" target="_blank">Gene Designer 2.0</a> - Free, robust sequence design application</p>
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<h2>Papers</h2>
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<p><a href="http://www.nature.com/nbt/journal/v26/n7/full/nbt1413.html" target="_blank">Refinement and standardization of synthetic biological parts and devices</a> - Canton, Labno, and Endy (2008)</p>
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<p><a href="http://www.sciencemag.org/content/280/5364/698.full" target="_blank">Can Patents Deter Innovation? The Anticommons in Biomedical Research</a> - Heller and Eisenberg (1998)</p>
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<p><a href="http://www.nature.com/nbt/journal/v19/n11/full/nbt1101-1029.html" target="_blank">Polymeric system for dual growth factor delivery</a> - Richardson, Peters, Ennett, Mooney (2001)</p>
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<p><a href="http://cardiovascres.oxfordjournals.org/content/75/1/178.full" target="_blank">Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction</a> - Hao, Silva, Månsson-Broberg, Grinnemo, Siddiqui, Dellgren, Wärdell, Brodin, Mooney, and Sylvén (2007)</p>
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<p><a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1538-7836.2007.02386.x/abstract;jsessionid=A31E91687E6FCE39FF2C818707D0464D.d03t04" target="_blank">Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis</a> - Silva and Mooney (2007)</p>
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<p><a href="http://www.nature.com/nm/journal/v6/n4/full/nm0400_389.html" target="_blank">Mechanisms of angiogenesis and arteriogenesis</a> - Carmeliet (2000)</p>
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<p><a href="http://www.sciencedirect.com/science/article/pii/S0070215304640087" target="_blank">Synthetic Extracellular Matrices for Tissue Engineering and Regeneration</a> - Silva and Mooney (2004)</p>
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    </p>
 
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    <p>To access our detailed findings, <a href="#" >read our full paper here</a>.</p>
 
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Latest revision as of 04:04, 29 September 2011

iGEM - Team Virginia - Human Practices

Resources

Advice and Best Practices for Future iGEM Teams

Original research rarely goes according to plan. Many of your experiments will fail. Prepare for this by splitting your project into phases that can be completed in parallel.

Be very careful when ordering DNA synthesized by a third party. Especially be ware that by default you will be shipped single-stranded DNA, so you must specify "duplex" if you need double-stranded DNA.

Collaborate with other students from different disciplines. Their perspectives will challenge you to think in new ways about the problems at hand.

Take initiative, be willing to take responsibilities, and get active in seeking out and learning new techniques.

Be curious about a field you have not explored before entering the research group.

External Links

Tools

Reverse and/or Complimentary Sequences - Free, browser-based applet for manipulating sequences according to IUPAC conventions

Serial Cloner 2.1 - Free, light molecular biology utility

Gene Designer 2.0 - Free, robust sequence design application

Papers

Refinement and standardization of synthetic biological parts and devices - Canton, Labno, and Endy (2008)

Can Patents Deter Innovation? The Anticommons in Biomedical Research - Heller and Eisenberg (1998)

Polymeric system for dual growth factor delivery - Richardson, Peters, Ennett, Mooney (2001)

Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction - Hao, Silva, Månsson-Broberg, Grinnemo, Siddiqui, Dellgren, Wärdell, Brodin, Mooney, and Sylvén (2007)

Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis - Silva and Mooney (2007)

Mechanisms of angiogenesis and arteriogenesis - Carmeliet (2000)

Synthetic Extracellular Matrices for Tissue Engineering and Regeneration - Silva and Mooney (2004)

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