Team:UNAM-Genomics Mexico/Modeling/CA

From 2011.igem.org

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==Introduction==
==Introduction==
We have chosen to do a Cellular Automaton to corroborate two things:
We have chosen to do a Cellular Automaton to corroborate two things:
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* Double Check the Game Theory results with a nice shiny plot
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# Observe Plant development with the C vs N economy at the Niche
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* Observe Plant development with the C vs N economy at the Niche
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# Double Check the Game Theory results with a nice shiny plot
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==Tool==
==Tool==
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We will be using Rule-Based-Modelling approaches, id est [http://kappalanguage.org/ Kappa]. We are using the [http://kappamodeler.github.com/rulestudio/ RuleStudio] plugin for the [http://www.eclipse.org/ Eclipse] Environment / Suite. We have some past experience with Kappa, our model for last year's project [https://2010.igem.org/Team:UNAM-Genomics_Mexico/Modules/In_silico WiFi Coli] relied heavily on it, and we are lightly involved in the [http://groups.google.com/group/kappa-users Kappa users] community.
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We will be using Rule-Based-Modelling approaches, id est [http://kappalanguage.org/ Kappa]. We are using the [http://kappamodeler.github.com/rulestudio/ RuleStudio] plugin for the [http://www.eclipse.org/ Eclipse] Environment / Suite. We have some past experience with Kappa, our model for last year's project [https://2010.igem.org/Team:UNAM-Genomics_Mexico/Modules/In_silico WiFi Coli] relied heavily on it, and we are lightly involved in the [http://groups.google.com/group/kappa-users Kappa users] community. Our script is [https://2011.igem.org/File:UNAM-Genomics_Mexico_hmedina_Hydrobium_etli_Cellular_Automaton.txt here].
We've tried using the [http://rulebase.org/ online version], however it is not as compatible as we would like it to be with Chrome, Firefox, or Internet Explorer...
We've tried using the [http://rulebase.org/ online version], however it is not as compatible as we would like it to be with Chrome, Firefox, or Internet Explorer...
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==Results==
==Results==
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Still running!
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Our CA behaved as expected. Here are the results we got.
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===C vs N economy===
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We can see first and foremost that with the addition of our transgenic chassis, the final count of plants is higher at around 70 plants. This reflect the [https://2011.igem.org/File:UNAM-Genomics_Mexico_hmedina_Hydrobium_etli_Cellular_Automaton201109281826.txt first scenario] of enhanced nitrogen fixation. For the [https://2011.igem.org/File:UNAM-Genomics_Mexico_hmedina_Hydrobium_etli_Cellular_Automaton201109281827.txt "purist" scenario] of only wildtypes, plant count is lower at around 50.
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===GT===
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Still running!
}}
}}

Revision as of 23:41, 28 September 2011

UNAM-Genomics_Mexico


Introduction

We have chosen to do a Cellular Automaton to corroborate two things:

  1. Observe Plant development with the C vs N economy at the Niche
  2. Double Check the Game Theory results with a nice shiny plot


Background

Cellular Automatons rely on rules to calculate the next state, from t to t+1. Kappa uses rules to extrapolate differential equations (via the über-strange concept of "Fragments") and thus obtain the changes from application, to application. Seeing the analogy of these approaches, we chose to do our CA with Kappa.


Tool

We will be using Rule-Based-Modelling approaches, id est [http://kappalanguage.org/ Kappa]. We are using the [http://kappamodeler.github.com/rulestudio/ RuleStudio] plugin for the [http://www.eclipse.org/ Eclipse] Environment / Suite. We have some past experience with Kappa, our model for last year's project WiFi Coli relied heavily on it, and we are lightly involved in the [http://groups.google.com/group/kappa-users Kappa users] community. Our script is here.

We've tried using the [http://rulebase.org/ online version], however it is not as compatible as we would like it to be with Chrome, Firefox, or Internet Explorer...


Results

Our CA behaved as expected. Here are the results we got.


C vs N economy

We can see first and foremost that with the addition of our transgenic chassis, the final count of plants is higher at around 70 plants. This reflect the first scenario of enhanced nitrogen fixation. For the "purist" scenario of only wildtypes, plant count is lower at around 50.


GT

Still running!