Team:Grenoble/Projet/Modelling
From 2011.igem.org
JeanBaptiste (Talk | contribs) |
JeanBaptiste (Talk | contribs) |
||
Line 11: | Line 11: | ||
<div class="left"> | <div class="left"> | ||
<h1>Modelling</h1> | <h1>Modelling</h1> | ||
- | <div class="blocbackground"> | + | <div class="blocbackground" id="Content"> |
<h2>Table of content</h2> | <h2>Table of content</h2> | ||
<p> | <p> | ||
Line 52: | Line 52: | ||
</div> | </div> | ||
<form method="get"> | <form method="get"> | ||
- | <select name="id" onchange="document.location = '/Team:Grenoble/Projet/Modelling | + | <select name="id" onchange="document.location = '/Team:Grenoble/Projet/Modelling' + this.options[this.selectedIndex].value ;"> |
- | + | ||
+ | <optgroup label="Modelling Homepage"> | ||
+ | |||
+ | <option value="#Content" selected="selected">Table of content</option> | ||
+ | |||
+ | </optgroup> | ||
+ | |||
+ | <optgroup label="Deterministic Modelling" > | ||
- | <option value="Deterministic#Our_equations | + | <option value="/Deterministic#Our_equations" >Our equations</option> |
- | <option value="Deterministic#Our_algorithms" >Our algorithms</option> | + | <option value="/Deterministic#Our_algorithms" >Our algorithms</option> |
- | <option value="Deterministic#Isoclines">Isoclines and Hysteresis</option> | + | <option value="/Deterministic#Isoclines">Isoclines and Hysteresis</option> |
Line 67: | Line 73: | ||
<optgroup label="Stochastic Modelling"> | <optgroup label="Stochastic Modelling"> | ||
- | <option value="Stochastic#Geof">Geof's</option> | + | <option value="/Stochastic#Geof">Geof's</option> |
- | <option value="Stochastic#Gillespie_algorithm">Gillespie algorithm</option> | + | <option value="/Stochastic#Gillespie_algorithm">Gillespie algorithm</option> |
- | <option value="Stochastic#Stats">Mean, standard deviation and stats</option> | + | <option value="/Stochastic#Stats">Mean, standard deviation and stats</option> |
</optgroup> | </optgroup> | ||
Line 77: | Line 83: | ||
<optgroup label="Parameters"> | <optgroup label="Parameters"> | ||
- | <option value="Parameters">Our parameters</option> | + | <option value="/Parameters">Our parameters</option> |
</optgroup> | </optgroup> | ||
Line 83: | Line 89: | ||
<optgroup label="Results"> | <optgroup label="Results"> | ||
- | <option value="Results#Validation">Validation of our Network</option> | + | <option value="/Results#Validation">Validation of our Network</option> |
- | <option value="Results#Device">Device specificities</option> | + | <option value="/Results#Device">Device specificities</option> |
</optgroup> | </optgroup> |
Revision as of 13:30, 18 September 2011
Modelling
Table of content
Our synthetic biology constructions feature tens of parameters and at this scale human brains can only guess how the whole system would work. We of course needed mathematical modelling in order to check the effectiveness of the genetic circuit.
In the particular case of our circuit and final use of the bacteria, the modelling team also had to give the specificities (size, number of bacteria, IPTG gradient specificities) of the measuring device we intend to produce.
In the next pages we expose which algorithms we used for both deterministic modelling and stochastic modelling, explain our MATLAB scripts (available here) and finally give the results of our simulations.
Deterministic Modelling :
Our equations and how we obtained them.
Our algorithms
Isoclines and Hysteresis
Stochastic Modelling :
Geoffrey
Gillespie algorithm
Mean, standard deviation and statistical properties
Parameters
Results :
Validation of our genetical network
Device