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Team:Imperial College London/Templates/Kill
From 2011.igem.org
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<li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Modelling">Modelling</a></li> | <li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Modelling">Modelling</a></li> | ||
<li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Assembly">Assembly</a></li> | <li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Assembly">Assembly</a></li> | ||
| - | <li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Testing">Testing</a></li> | + | <li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Testing">Testing & Results</a></li> |
<li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Future">Future Work</a></li> | <li><a href="https://2011.igem.org/Team:Imperial_College_London/Project_Gene_Future">Future Work</a></li> | ||
</ul> | </ul> | ||
Revision as of 13:22, 17 September 2011
Module 3: Gene Guard
Containment is a serious issue concerning the release of GMOs into the environment. To prevent horizontal gene transfer of the genes we have expressed in our chassis, we have developed a toxin/anti-toxin system based on the genes encoding holin and anti-holin. We are designing our bacteria to contain anti-holin (the anti-toxin) within its genome and holin & endolysin on the plasmid with the Phyto-Route and Auxin Xpress genes. In the event of horizontal gene transfer with a soil bacterium, holin and endolysin would be transferred without anti-holin, effectively killing the recipient cell.
