Reaction Name: arabinose 5 phosphate isomerase Estimated Flux: 4.251740e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Ribulose_5_phosphate <=> D_Arabinose_5_phosphate Reaction Name: acyl acyl carrier protein synthetase n C140 Estimated Flux: 1.244007e-027 mmol gDW- 1 h- 1 Reaction Formula: acyl_carrier_protein + ATP + tetradecanoate__n_C140_ -> AMP + Myristoyl_ACP__n_C140ACP_ + Diphosphate b2836 Reaction Name: acyl acyl carrier protein synthetase n C141 Estimated Flux: 2.745395e-029 mmol gDW- 1 h- 1 Reaction Formula: acyl_carrier_protein + ATP + tetradecenoate__n_C141_ -> AMP + Diphosphate + cis_tetradec_7_enoyl_acyl_carrier_protein__n_C141_ b2836 Reaction Name: acyl acyl carrier protein synthetase n C160 Estimated Flux: 9.978627e-029 mmol gDW- 1 h- 1 Reaction Formula: acyl_carrier_protein + ATP + Hexadecanoate__n_C160_ -> AMP + Palmitoyl_ACP__n_C160ACP_ + Diphosphate b2836 Reaction Name: acetyl CoA carboxylase reversible reaction Estimated Flux: 2.335204e+000 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + ATP + Bicarbonate <=> ADP + H + Malonyl_CoA + Phosphate ( b0185 and b2316 and b3255 and b3256 ) Reaction Name: acetate CoA ligase ADP forming Estimated Flux: 1000 mmol gDW- 1 h- 1 Reaction Formula: ATP + Coenzyme_A + Propionate__n_C30_ -> ADP + Phosphate + Propanoyl_CoA b0335 Reaction Name: acetylglutamate kinase Estimated Flux: 3.269791e-001 mmol gDW- 1 h- 1 Reaction Formula: N_Acetyl_L_glutamate + ATP -> N_Acetyl_L_glutamyl_5_phosphate + ADP b3959 Reaction Name: N acetylglutamate synthase Estimated Flux: 3.269791e-001 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + L_Glutamate -> N_Acetyl_L_glutamate + Coenzyme_A + H b2818 Reaction Name: 2 aceto 2 hydroxybutanoate synthase Estimated Flux: 2.794001e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxobutanoate + H + Pyruvate -> S__2_Aceto_2_hydroxybutanoate + CO2 ( ( b3670 and b3671 ) or ( b3767 and b3768 and b3769 ) or ( b0077 and b0078 ) ) Reaction Name: acetate kinase Estimated Flux: -3.116790e+000 mmol gDW- 1 h- 1 Reaction Formula: Acetate + ATP <=> Acetyl_phosphate + ADP ( b2296 or b1849 or b3115 ) Reaction Name: acetolactate synthase Estimated Flux: 8.402845e-001 mmol gDW- 1 h- 1 Reaction Formula: H + 2.000000 Pyruvate -> S__2_Acetolactate + CO2 ( ( b3670 and b3671 ) or ( b3767 and b3768 and b3769 ) or ( b0077 and b0078 ) ) Reaction Name: acetylornithine deacetylase Estimated Flux: 3.269791e-001 mmol gDW- 1 h- 1 Reaction Formula: N2_Acetyl_L_ornithine + H2O -> Acetate + Ornithine b3957 Reaction Name: aconitase Estimated Flux: 3.312211e+000 mmol gDW- 1 h- 1 Reaction Formula: Citrate <=> Isocitrate ( b1276 or b0118 ) Reaction Name: acetylornithine transaminase Estimated Flux: -3.269791e-001 mmol gDW- 1 h- 1 Reaction Formula: N2_Acetyl_L_ornithine + 2_Oxoglutarate <=> N_Acetyl_L_glutamate_5_semialdehyde + L_Glutamate b3359 Reaction Name: acetate reversible transport via proton symport Estimated Flux: -3.696706e+000 mmol gDW- 1 h- 1 Reaction Formula: Acetate + H <=> Acetate + H Reaction Name: 4 aminobenzoate synthase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: 4_amino_4_deoxychorismate -> 4_Aminobenzoate + H + Pyruvate b1096 Reaction Name: 4 amino 4 deoxychorismate synthase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: chorismate + L_Glutamine -> 4_amino_4_deoxychorismate + L_Glutamate ( b3360 and b1812 ) Reaction Name: adenylate kinase Estimated Flux: 1000 mmol gDW- 1 h- 1 Reaction Formula: AMP + ATP <=> 2.000000 ADP b0474 Reaction Name: adentylate kinase GTP Estimated Flux: -9.976621e+002 mmol gDW- 1 h- 1 Reaction Formula: AMP + GTP <=> ADP + GDP b0474 Reaction Name: Adenosylmethionine decarboxylase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: S_Adenosyl_L_methionine + H <=> S_Adenosylmethioninamine + CO2 b0120 Reaction Name: adenosine kinase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: Adenosine + ATP -> ADP + AMP + H b0474 Reaction Name: adenosine transport in via proton symport Estimated Flux: 1000 mmol gDW- 1 h- 1 Reaction Formula: Adenosine + H -> Adenosine + H ( b2964 or b2393 ) Reaction Name: adenosine transport in via proton symport reversible Estimated Flux: -1.000000e+003 mmol gDW- 1 h- 1 Reaction Formula: Adenosine + H <=> Adenosine + H b2406 Reaction Name: adenylyl sulfate kinase Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: Adenosine_5__phosphosulfate + ATP -> ADP + H + 3__Phosphoadenylyl_sulfate b2750 Reaction Name: adenylsuccinate lyase Estimated Flux: 2.930654e-001 mmol gDW- 1 h- 1 Reaction Formula: N6__1_2_Dicarboxyethyl__AMP <=> AMP + Fumarate b1131 Reaction Name: adenylosuccinate lyase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: S__2_5_Amino_1__5_phospho_D_ribosyl_imidazole_4_carboxamidosuccinate <=> 5_Amino_1__5_Phospho_D_ribosyl_imidazole_4_carboxamide + Fumarate b1131 Reaction Name: adenylosuccinate synthase Estimated Flux: 2.930654e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + GTP + IMP -> N6__1_2_Dicarboxyethyl__AMP + GDP + 2.000000 H + Phosphate b4177 Reaction Name: ADP D glycero D manno heptose epimerase Estimated Flux: 2.551044e-002 mmol gDW- 1 h- 1 Reaction Formula: ADP_D_glycero_D_manno_heptose -> ADP_L_glycero_D_manno_heptose b3619 Reaction Name: N acetyl g glutamyl phosphate reductase Estimated Flux: -3.269791e-001 mmol gDW- 1 h- 1 Reaction Formula: N_Acetyl_L_glutamate_5_semialdehyde + Nicotinamide_adenine_dinucleotide_phosphate + Phosphate <=> N_Acetyl_L_glutamyl_5_phosphate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced b3958 Reaction Name: adenosylhomocysteinase Estimated Flux: -6.521965e-017 mmol gDW- 1 h- 1 Reaction Formula: S_Adenosyl_L_homocysteine + H2O <=> Adenosine + L_Homocysteine Reaction Name: phosphoribosylaminoimidazolecarboxamide formyltransferase Estimated Flux: 5.749051e-001 mmol gDW- 1 h- 1 Reaction Formula: 10_Formyltetrahydrofolate + 5_Amino_1__5_Phospho_D_ribosyl_imidazole_4_carboxamide <=> 5_Formamido_1__5_phospho_D_ribosyl_imidazole_4_carboxamide + 5_6_7_8_Tetrahydrofolate b4006 Reaction Name: phosphoribosylaminoimidazole carboxylase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: 5_amino_1__5_phospho_D_ribosyl_imidazole + ATP + Bicarbonate -> 5_phosphoribosyl_5_carboxyaminoimidazole + ADP + H + Phosphate b0522 Reaction Name: phosphoribosylaminoimidazole carboxylase mutase rxn Estimated Flux: -4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: 5_amino_1__5_phospho_D_ribosyl_imidazole_4_carboxylate <=> 5_phosphoribosyl_5_carboxyaminoimidazole b0523 Reaction Name: 2 Oxogluterate dehydrogenase Estimated Flux: 2.187929e+000 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + Coenzyme_A + Nicotinamide_adenine_dinucleotide -> CO2 + Nicotinamide_adenine_dinucleotide___reduced + Succinyl_CoA ( b0116 and b0726 and b0727 ) Reaction Name: D alanine D alanine ligase reversible Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: 2.000000 D_Alanine + ATP <=> ADP + D_Alanyl_D_alanine + H + Phosphate ( b0381 or b0092 ) Reaction Name: alanine racemase Estimated Flux: -9.999441e+002 mmol gDW- 1 h- 1 Reaction Formula: L_Alanine <=> D_Alanine b4053 Reaction Name: alanine racemase irreversible Estimated Flux: 1000 mmol gDW- 1 h- 1 Reaction Formula: L_Alanine -> D_Alanine b1190 Reaction Name: L alanine transaminase Estimated Flux: -1000 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + L_Alanine <=> L_Glutamate + Pyruvate Reaction Name: S adenosylmethione2 demethylmenaquinone methyltransferase Estimated Flux: -6.521965e-017 mmol gDW- 1 h- 1 Reaction Formula: 2_Demethylmenaquinone_8 + S_Adenosyl_L_methionine -> S_Adenosyl_L_homocysteine + H + Menaquinone_8 b3929 Reaction Name: anthranilate phosphoribosyltransferase Estimated Flux: 5.466523e-002 mmol gDW- 1 h- 1 Reaction Formula: Anthranilate + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + N__5_Phospho_D_ribosyl_anthranilate b1263 Reaction Name: anthranilate synthase Estimated Flux: 5.466523e-002 mmol gDW- 1 h- 1 Reaction Formula: chorismate + L_Glutamine -> Anthranilate + L_Glutamate + H + Pyruvate ( b1263 and b1264 ) Reaction Name: 5 amino 6 5 phosphoribosylamino uracil reductase Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: 5_Amino_6__5__phosphoribosylamino_uracil + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 5_Amino_6__5__phosphoribitylamino_uracil + Nicotinamide_adenine_dinucleotide_phosphate b0414 Reaction Name: argininosuccinate lyase Estimated Flux: 2.844617e-001 mmol gDW- 1 h- 1 Reaction Formula: N_omega___L_Arginino_succinate <=> L_Arginine + Fumarate b3960 Reaction Name: argininosuccinate synthase Estimated Flux: 2.844617e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + ATP + L_Citrulline -> AMP + N_omega___L_Arginino_succinate + H + Diphosphate b3172 Reaction Name: aspartate semialdehyde dehydrogenase Estimated Flux: -5.057546e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate_4_semialdehyde + Nicotinamide_adenine_dinucleotide_phosphate + Phosphate <=> 4_Phospho_L_aspartate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced b3433 Reaction Name: asparagine synthetase Estimated Flux: 2.318211e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + ATP + Ammonium -> AMP + L_Asparagine + H + Diphosphate b3744 Reaction Name: aspartate 1 decarboxylase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + H -> beta_Alanine + CO2 b0131 Reaction Name: aspartate carbamoyltransferase Estimated Flux: 3.189817e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + Carbamoyl_phosphate -> N_Carbamoyl_L_aspartate + H + Phosphate ( b4244 and b4245 ) Reaction Name: aspartate kinase Estimated Flux: 5.057546e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + ATP <=> 4_Phospho_L_aspartate + ADP ( b0002 or b3940 or b4024 ) Reaction Name: L aspartate oxidase Estimated Flux: 2.763631e-003 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate + Fumarate -> Iminoaspartate + Succinate b2574 Reaction Name: aspartate transaminase Estimated Flux: -2.352525e+000 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + L_Aspartate <=> L_Glutamate + Oxaloacetate b0928 Reaction Name: ATP maintenance requirement Estimated Flux: 7.600000e+000 mmol gDW- 1 h- 1 Reaction Formula: ATP + H2O -> ADP + H + Phosphate Reaction Name: ATP phosphoribosyltransferase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + 1__5_Phosphoribosyl__ATP b2019 Reaction Name: ATP synthase four protons for one ATP Estimated Flux: 5.506908e+001 mmol gDW- 1 h- 1 Reaction Formula: ADP + 4.000000 H + Phosphate <=> ATP + H2O + 3.000000 H ( ( b3736 and b3737 and b3738 ) and ( b3731 and b3732 and b3733 and b3734 and b3735 ) and b3739 ) Reaction Name: 3 5 bisphosphate nucleotidase Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: H2O + Adenosine_3__5__bisphosphate -> AMP + Phosphate Reaction Name: BiomassEcoli Estimated Flux: 1.012319e+000 mmol gDW- 1 h- 1 Reaction Formula: 0.050000 5_Methyltetrahydrofolate + 0.000050 Acetyl_CoA + 0.488000 L_Alanine + 0.001000 AMP + 0.281000 L_Arginine + 0.229000 L_Asparagine + 0.229000 L_Aspartate + 45.731800 ATP + 0.000129 Cardiolipin__Ecoli_ + 0.000006 Coenzyme_A + 0.126000 CTP + 0.087000 L_Cysteine + 0.024700 dATP + 0.025400 dCTP + 0.025400 dGTP + 0.024700 dTTP + 0.000010 Flavin_adenine_dinucleotide_oxidized + 0.250000 L_Glutamine + 0.250000 L_Glutamate + 0.582000 Glycine + 0.154000 glycogen + 0.203000 GTP + 45.560800 H2O + 0.090000 L_Histidine + 0.276000 L_Isoleucine + 0.428000 L_Leucine + 0.008400 lipopolysaccharide__Ecoli_ + 0.326000 L_Lysine + 0.146000 L_Methionine + 0.002150 Nicotinamide_adenine_dinucleotide + 0.000050 Nicotinamide_adenine_dinucleotide___reduced + 0.000130 Nicotinamide_adenine_dinucleotide_phosphate + 0.000400 Nicotinamide_adenine_dinucleotide_phosphate___reduced + 0.001935 Phosphatidylethanolamine__ecoli_ + 0.027600 Peptidoglycan_subunit_of_Escherichia_coli + 0.000464 Phosphatidylglycerol__Ecoli_ + 0.176000 L_Phenylalanine + 0.210000 L_Proline + 0.000052 phosphatidylserine__Ecoli_ + 0.035000 Putrescine + 0.205000 L_Serine + 0.007000 Spermidine + 0.000003 Succinyl_CoA + 0.241000 L_Threonine + 0.054000 L_Tryptophan + 0.131000 L_Tyrosine + 0.003000 UDPglucose + 0.136000 UTP + 0.402000 L_Valine -> 45.560800 ADP + 45.560350 H + 45.562800 Phosphate + 0.730200 Diphosphate Reaction Name: Fatty acid biosynthesis n C120 Estimated Flux: 4.251740e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetoacetyl_ACP + 14.000000 H + 4.000000 Malonyl_acyl_carrier_protein + 10.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 4.000000 acyl_carrier_protein + 4.000000 CO2 + Dodecanoyl_ACP__n_C120ACP_ + 5.000000 H2O + 10.000000 Nicotinamide_adenine_dinucleotide_phosphate ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) ) Reaction Name: Fatty acid biosynthesis n C140 Estimated Flux: 1.398822e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetoacetyl_ACP + 17.000000 H + 5.000000 Malonyl_acyl_carrier_protein + 12.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 5.000000 acyl_carrier_protein + 5.000000 CO2 + 6.000000 H2O + Myristoyl_ACP__n_C140ACP_ + 12.000000 Nicotinamide_adenine_dinucleotide_phosphate ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) ) Reaction Name: Fatty acid biosynthesis n C141 Estimated Flux: 1.371186e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetoacetyl_ACP + 16.000000 H + 5.000000 Malonyl_acyl_carrier_protein + 11.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 5.000000 acyl_carrier_protein + 5.000000 CO2 + 6.000000 H2O + 11.000000 Nicotinamide_adenine_dinucleotide_phosphate + cis_tetradec_7_enoyl_acyl_carrier_protein__n_C141_ ( b0954 and b2323 and b1093 and b1288 and b0180 ) Reaction Name: Fatty acid biosynthesis n C160 Estimated Flux: 9.872540e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetoacetyl_ACP + 20.000000 H + 6.000000 Malonyl_acyl_carrier_protein + 14.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 6.000000 acyl_carrier_protein + 6.000000 CO2 + 7.000000 H2O + 14.000000 Nicotinamide_adenine_dinucleotide_phosphate + Palmitoyl_ACP__n_C160ACP_ ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) ) Reaction Name: Fatty acid biosynthesis n C161 Estimated Flux: 1.919661e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetoacetyl_ACP + 19.000000 H + 6.000000 Malonyl_acyl_carrier_protein + 13.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 6.000000 acyl_carrier_protein + 6.000000 CO2 + 7.000000 H2O + cis_hexadec_9_enoyl_acyl_carrier_protein__n_C161_ + 13.000000 Nicotinamide_adenine_dinucleotide_phosphate ( b0954 and b2323 and b1093 and b1288 and b0180 ) Reaction Name: Fatty acid biosynthesis n C181 Estimated Flux: 1.371186e-001 mmol gDW- 1 h- 1 Reaction Formula: Acetoacetyl_ACP + 22.000000 H + 7.000000 Malonyl_acyl_carrier_protein + 15.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced -> 7.000000 acyl_carrier_protein + 7.000000 CO2 + 8.000000 H2O + 15.000000 Nicotinamide_adenine_dinucleotide_phosphate + cis_octadec_11_enoyl_acyl_carrier_protein__n_C181_ ( b0954 and b2323 and b1095 and b1093 and b1288 and b0180 ) Reaction Name: Carbamate kinase Estimated Flux: 6.034434e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + CO2 + Ammonium -> ADP + Carbamoyl_phosphate + 2.000000 H ( b0521 or b2874 or b0323 ) Reaction Name: chorismate mutase Estimated Flux: 3.107820e-001 mmol gDW- 1 h- 1 Reaction Formula: chorismate -> Prephenate ( b2599 or b2600 ) Reaction Name: chorismate synthase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: 5_O__1_Carboxyvinyl__3_phosphoshikimate -> chorismate + Phosphate b2329 Reaction Name: Cardiolipin Synthase Ecoli Estimated Flux: 6.529458e-003 mmol gDW- 1 h- 1 Reaction Formula: 0.040000 Phosphatidylglycerol__Ecoli_ <=> 0.020000 Cardiolipin__Ecoli_ + Glycerol b1249 Reaction Name: CO2 transporter via diffusion Estimated Flux: -2.203693e+001 mmol gDW- 1 h- 1 Reaction Formula: CO2 <=> CO2 Reaction Name: citrate synthase Estimated Flux: 3.312211e+000 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + H2O + Oxaloacetate -> Citrate + Coenzyme_A + H b0720 Reaction Name: CTP synthase glutamine Estimated Flux: 1.532651e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + L_Glutamine + H2O + UTP -> ADP + CTP + L_Glutamate + 2.000000 H + Phosphate b2780 Reaction Name: cysteine synthase Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: O_Acetyl_L_serine + Hydrogen_sulfide -> Acetate + L_Cysteine + H ( b2414 or b2421 ) Reaction Name: cystathionine b lyase Estimated Flux: 1.477986e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Cystathionine + H2O -> L_Homocysteine + Ammonium + Pyruvate ( b3008 or b1622 ) Reaction Name: cytochrome oxidase bo3 ubiquinol 8 25 protons Estimated Flux: 4.000000e+001 mmol gDW- 1 h- 1 Reaction Formula: 2.500000 H + 0.500000 O2 + Ubiquinol_8 -> H2O + 2.500000 H + Ubiquinone_8 ( b0429 and b0430 and b0431 and b0432 ) Reaction Name: cytidylate kinase CMP Estimated Flux: 1.796957e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + CMP <=> ADP + CDP b0910 Reaction Name: deoxyadenylate kinase Estimated Flux: 2.049482e-026 mmol gDW- 1 h- 1 Reaction Formula: ATP + dAMP <=> ADP + dADP b0474 Reaction Name: Diacylglycerol kinase Estimated Flux: 1.700696e-002 mmol gDW- 1 h- 1 Reaction Formula: 0.020000 1_2_Diacylglycerol___Ecoli_ + ATP -> ADP + H + 0.020000 phosphatidate___Ecoli_ b4042 Reaction Name: diaminopimelate decarboxylase Estimated Flux: 3.300160e-001 mmol gDW- 1 h- 1 Reaction Formula: meso_2_6_Diaminoheptanedioate + H -> CO2 + L_Lysine b2838 Reaction Name: diaminopimelate epimerase Estimated Flux: 3.579560e-001 mmol gDW- 1 h- 1 Reaction Formula: LL_2_6_Diaminoheptanedioate <=> meso_2_6_Diaminoheptanedioate b3809 Reaction Name: CDP Diacylglycerol synthetase Ecoli Estimated Flux: 1.541256e-001 mmol gDW- 1 h- 1 Reaction Formula: CTP + H + 0.020000 phosphatidate___Ecoli_ <=> 0.020000 CDPdiacylglycerol__E_coli_ + Diphosphate b0175 Reaction Name: 3 4 Dihydroxy 2 butanone 4 phosphate synthase Estimated Flux: 2.024638e-005 mmol gDW- 1 h- 1 Reaction Formula: D_Ribulose_5_phosphate -> 3_4_dihydroxy_2_butanone_4_phosphate + Formate + H b3041 Reaction Name: 3 deoxy D arabino heptulosonate 7 phosphate synthetase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: D_Erythrose_4_phosphate + H2O + Phosphoenolpyruvate -> 2_Dehydro_3_deoxy_D_arabino_heptonate_7_phosphate + Phosphate ( b2601 or b0754 or b1704 ) Reaction Name: deoxyguanylate kinase dGMPATP Estimated Flux: -5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + dGMP <=> ADP + dGDP b3648 Reaction Name: dihydroxy acid dehydratase 2 3 dihydroxy 3 methylbutanoate Estimated Flux: 8.402845e-001 mmol gDW- 1 h- 1 Reaction Formula: R__2_3_Dihydroxy_3_methylbutanoate -> 3_Methyl_2_oxobutanoate + H2O b3771 Reaction Name: Dihydroxy acid dehydratase 2 3 dihydroxy 3 methylpentanoate Estimated Flux: 2.794001e-001 mmol gDW- 1 h- 1 Reaction Formula: R__2_3_Dihydroxy_3_methylpentanoate -> S__3_Methyl_2_oxopentanoate + H2O b3771 Reaction Name: dihydrodipicolinate reductase NADPH Estimated Flux: 3.579560e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_3_Dihydrodipicolinate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> Nicotinamide_adenine_dinucleotide_phosphate + 2_3_4_5_Tetrahydrodipicolinate b0031 Reaction Name: dihydrodipicolinate synthase Estimated Flux: 3.579560e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Aspartate_4_semialdehyde + Pyruvate -> 2_3_Dihydrodipicolinate + 2.000000 H2O + H b2478 Reaction Name: dihydrofolate reductase Estimated Flux: 7.562023e-002 mmol gDW- 1 h- 1 Reaction Formula: 7_8_Dihydrofolate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced <=> Nicotinamide_adenine_dinucleotide_phosphate + 5_6_7_8_Tetrahydrofolate b0048 Reaction Name: dihydrofolate synthase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + Dihydropteroate + L_Glutamate -> ADP + 7_8_Dihydrofolate + Phosphate b2315 Reaction Name: 1 4 dihydroxy 2 naphthoate octaprenyltransferase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: 1_4_Dihydroxy_2_naphthoate + all_trans_Octaprenyl_diphosphate -> 2_Demethylmenaquinone_8 + CO2 + H + Diphosphate b3930 Reaction Name: dihydroneopterin aldolase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: Dihydroneopterin -> 6_hydroxymethyl_dihydropterin + Glycolaldehyde b3058 Reaction Name: dihydroorotic acid menaquinone 8 Estimated Flux: 3.189817e-001 mmol gDW- 1 h- 1 Reaction Formula: S__Dihydroorotate + Menaquinone_8 -> Menaquinol_8 + Orotate b0945 Reaction Name: dihydroorotase Estimated Flux: -3.189817e-001 mmol gDW- 1 h- 1 Reaction Formula: S__Dihydroorotate + H2O <=> N_Carbamoyl_L_aspartate + H b1062 Reaction Name: diaminohydroxyphosphoribosylaminopryrimidine deaminase 25drapp Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: 2_5_Diamino_6__ribosylamino__4__3H__pyrimidinone_5__phosphate + H2O + H -> 5_Amino_6__5__phosphoribosylamino_uracil + Ammonium b0414 Reaction Name: dihydropteroate synthase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: 4_Aminobenzoate + 6_hydroxymethyl_dihydropterin_pyrophosphate -> Dihydropteroate + H + Diphosphate b3177 Reaction Name: 3 dehydroquinate dehydratase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: 3_Dehydroquinate <=> 3_Dehydroshikimate + H2O b1693 Reaction Name: 3 dehydroquinate synthase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Dehydro_3_deoxy_D_arabino_heptonate_7_phosphate -> 3_Dehydroquinate + Phosphate b3389 Reaction Name: 2 3 diketo 5 methylthio 1 phosphopentane degradation reaction Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: 2_3_diketo_5_methylthio_1_phosphopentane + 3.000000 H2O -> 2_keto_4_methylthiobutyrate + Formate + 6.000000 H + Phosphate Reaction Name: dimethylallyltranstransferase Estimated Flux: -2.014782e-018 mmol gDW- 1 h- 1 Reaction Formula: Dimethylallyl_diphosphate + Isopentenyl_diphosphate -> Geranyl_diphosphate + Diphosphate b0421 Reaction Name: Dihydroneopterin monophosphate dephosphorylase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: Dihydroneopterin_monophosphate + H2O -> Dihydroneopterin + Phosphate Reaction Name: Dihydroneopterin triphosphate pyrophosphatase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: 2_Amino_4_hydroxy_6__erythro_1_2_3_trihydroxypropyl_dihydropteridine_triphosphate + H2O -> Dihydroneopterin_monophosphate + H + Diphosphate ( b1865 or b0099 ) Reaction Name: dephospho CoA kinase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: ATP + Dephospho_CoA -> ADP + Coenzyme_A + H Reaction Name: 2 dehydropantoate 2 reductase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: 2_Dehydropantoate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> Nicotinamide_adenine_dinucleotide_phosphate + R__Pantoate ( b0425 or b3774 ) Reaction Name: deoxyribose phosphate aldolase Estimated Flux: 5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Deoxy_D_ribose_5_phosphate -> Acetaldehyde + Glyceraldehyde_3_phosphate b4381 Reaction Name: dTMP kinase Estimated Flux: 2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + dTMP <=> ADP + dTDP b1098 Reaction Name: deoxyuridine phosphorylase Estimated Flux: 8.160820e-027 mmol gDW- 1 h- 1 Reaction Formula: Deoxyuridine + Phosphate <=> 2_Deoxy_D_ribose_1_phosphate + Uracil ( b4382 or b4384 ) Reaction Name: Endotoxin Synthesis lauroyl transferase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: Dodecanoyl_ACP__n_C120ACP_ + KDO_2__lipid_IV_A_ -> acyl_carrier_protein + KDO_2__lipid_IV_A__with_laurate b1054 Reaction Name: Endotoxin Synthesis myristoyl transferase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: KDO_2__lipid_IV_A__with_laurate + Myristoyl_ACP__n_C140ACP_ -> acyl_carrier_protein + KDO_2__lipid__A_ b1855 Reaction Name: enolase Estimated Flux: 1.617399e+001 mmol gDW- 1 h- 1 Reaction Formula: D_Glycerate_2_phosphate <=> H2O + Phosphoenolpyruvate b2779 Reaction Name: Ethanolamine ammonia lyase Estimated Flux: 6.621968e-029 mmol gDW- 1 h- 1 Reaction Formula: Ethanolamine -> Acetaldehyde + Ammonium ( b2440 and b2441 ) Reaction Name: Acetate exchange Estimated Flux: 3.696706e+000 mmol gDW- 1 h- 1 Reaction Formula: Acetate <=> Reaction Name: CO2 exchange Estimated Flux: 2.203693e+001 mmol gDW- 1 h- 1 Reaction Formula: CO2 <=> Reaction Name: D Glucose exchange Estimated Flux: -1.190000e+001 mmol gDW- 1 h- 1 Reaction Formula: D_Glucose <=> Reaction Name: H2O exchange Estimated Flux: 4.345336e+001 mmol gDW- 1 h- 1 Reaction Formula: H2O <=> Reaction Name: H exchange Estimated Flux: 1.297868e+001 mmol gDW- 1 h- 1 Reaction Formula: H <=> Reaction Name: Ammonia exchange Estimated Flux: -1.081609e+001 mmol gDW- 1 h- 1 Reaction Formula: Ammonium <=> Reaction Name: O2 exchange Estimated Flux: -20 mmol gDW- 1 h- 1 Reaction Formula: O2 <=> Reaction Name: Phosphate exchange Estimated Flux: -9.228675e-001 mmol gDW- 1 h- 1 Reaction Formula: Phosphate <=> Reaction Name: Sulfate exchange Estimated Flux: -2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: Sulfate <=> Reaction Name: Thiamin exchange Estimated Flux: -5.453350e-034 mmol gDW- 1 h- 1 Reaction Formula: Thiamin <=> Reaction Name: fructose bisphosphate aldolase Estimated Flux: 8.237940e+000 mmol gDW- 1 h- 1 Reaction Formula: D_Fructose_1_6_bisphosphate <=> Dihydroxyacetone_phosphate + Glyceraldehyde_3_phosphate ( b2925 or b2097 or b1773 ) Reaction Name: formate dehydrogenase quinone 8 2 protons Estimated Flux: 3.718876e-001 mmol gDW- 1 h- 1 Reaction Formula: Formate + 3.000000 H + Ubiquinone_8 -> CO2 + 2.000000 H + Ubiquinol_8 ( ( b1474 and b1475 and b1476 ) or ( b3892 and b3893 and b3894 ) or b4079 ) Reaction Name: FMN adenylyltransferase Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: ATP + FMN + H -> Flavin_adenine_dinucleotide_oxidized + Diphosphate b0025 Reaction Name: fumarate reductase Estimated Flux: 3.189817e-001 mmol gDW- 1 h- 1 Reaction Formula: Fumarate + Menaquinol_8 -> Menaquinone_8 + Succinate ( b4151 and b4152 and b4153 and b4154 ) Reaction Name: fumarate reductase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: 2_Demethylmenaquinol_8 + Fumarate -> 2_Demethylmenaquinone_8 + Succinate ( b4151 and b4152 and b4153 and b4154 ) Reaction Name: formyltetrahydrofolate deformylase Estimated Flux: 3.141550e-001 mmol gDW- 1 h- 1 Reaction Formula: 10_Formyltetrahydrofolate + H2O -> Formate + H + 5_6_7_8_Tetrahydrofolate b1232 Reaction Name: fumarase Estimated Flux: 3.249250e+000 mmol gDW- 1 h- 1 Reaction Formula: Fumarate + H2O <=> L_Malate ( b1612 or b4122 or b1611 ) Reaction Name: glucosamine 1 phosphate N acetyltransferase Estimated Flux: 7.288697e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + D_Glucosamine_1_phosphate -> N_Acetyl_D_glucosamine_1_phosphate + Coenzyme_A + H b3730 Reaction Name: glycerol 3 phosphate dehydrogenase NADP Estimated Flux: -1.671339e-001 mmol gDW- 1 h- 1 Reaction Formula: Glycerol_3_phosphate + Nicotinamide_adenine_dinucleotide_phosphate <=> Dihydroxyacetone_phosphate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced b3608 Reaction Name: L glutamate 5 semialdehyde dehydratase spontaneous Estimated Flux: 2.125870e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Glutamate_5_semialdehyde -> 1_Pyrroline_5_carboxylate + H2O + H Reaction Name: glutamate 5 semialdehyde dehydrogenase Estimated Flux: 2.125870e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Glutamate_5_phosphate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> L_Glutamate_5_semialdehyde + Nicotinamide_adenine_dinucleotide_phosphate + Phosphate b0243 Reaction Name: glucose 6 phosphate dehydrogenase Estimated Flux: 6.672975e+000 mmol gDW- 1 h- 1 Reaction Formula: D_Glucose_6_phosphate + Nicotinamide_adenine_dinucleotide_phosphate <=> 6_phospho_D_glucono_1_5_lactone + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced b1852 Reaction Name: UTP glucose 1 phosphate uridylyltransferase Estimated Flux: 2.004392e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Glucose_1_phosphate + H + UTP <=> Diphosphate + UDPglucose b1236 Reaction Name: glyceraldehyde 3 phosphate dehydrogenase Estimated Flux: 1.833137e+001 mmol gDW- 1 h- 1 Reaction Formula: Glyceraldehyde_3_phosphate + Nicotinamide_adenine_dinucleotide + Phosphate <=> 3_Phospho_D_glyceroyl_phosphate + H + Nicotinamide_adenine_dinucleotide___reduced ( b1779 or ( b1416 and b1417 ) ) Reaction Name: phosphoribosylglycinamide formyltransferase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: 10_Formyltetrahydrofolate + N1__5_Phospho_D_ribosyl_glycinamide <=> N2_Formyl_N1__5_phospho_D_ribosyl_glycinamide + H + 5_6_7_8_Tetrahydrofolate b2500 Reaction Name: Glycolaldehyde dehydrogenase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: Glycolaldehyde + H2O + Nicotinamide_adenine_dinucleotide -> Glycolate + 2.000000 H + Nicotinamide_adenine_dinucleotide___reduced b1415 Reaction Name: glutamine fructose 6 phosphate transaminase Estimated Flux: 7.288697e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Fructose_6_phosphate + L_Glutamine -> D_Glucosamine_6_phosphate + L_Glutamate b3729 Reaction Name: glycine hydroxymethyltransferase Estimated Flux: 1.596335e+000 mmol gDW- 1 h- 1 Reaction Formula: L_Serine + 5_6_7_8_Tetrahydrofolate -> Glycine + H2O + 5_10_Methylenetetrahydrofolate b2551 Reaction Name: guanylate kinase GMPATP Estimated Flux: 8.052087e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + GMP <=> ADP + GDP b3648 Reaction Name: glycogen synthase ADPGlc Estimated Flux: 1.558971e-001 mmol gDW- 1 h- 1 Reaction Formula: ADPglucose -> ADP + glycogen + H b3429 Reaction Name: D glucose transport via PEPPyr PTS Estimated Flux: 1.190000e+001 mmol gDW- 1 h- 1 Reaction Formula: D_Glucose + Phosphoenolpyruvate -> D_Glucose_6_phosphate + Pyruvate ( ( b2417 and b1101 and b2415 and b2416 ) or ( b2417 and b1621 and b2415 and b2416 ) or ( b1817 and b1818 and b1819 and b2415 and b2416 ) ) Reaction Name: glucose 1 phosphate adenylyltransferase Estimated Flux: 1.558971e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + D_Glucose_1_phosphate + H -> ADPglucose + Diphosphate b3430 Reaction Name: glutamine synthetase Estimated Flux: 1.925054e+000 mmol gDW- 1 h- 1 Reaction Formula: ATP + L_Glutamate + Ammonium -> ADP + L_Glutamine + H + Phosphate ( b3870 or b1297 ) Reaction Name: glutamate 5 kinase Estimated Flux: 2.125870e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + L_Glutamate -> ADP + L_Glutamate_5_phosphate b0242 Reaction Name: gamma glutamylcysteine synthetase Estimated Flux: 1.658905e-026 mmol gDW- 1 h- 1 Reaction Formula: ATP + L_Cysteine + L_Glutamate -> ADP + gamma_L_Glutamyl_L_cysteine + H + Phosphate b2688 Reaction Name: glutamate dehydrogenase NADP Estimated Flux: -8.425547e+000 mmol gDW- 1 h- 1 Reaction Formula: L_Glutamate + H2O + Nicotinamide_adenine_dinucleotide_phosphate <=> 2_Oxoglutarate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced + Ammonium b1761 Reaction Name: glutamine phosphoribosyldiphosphate amidotransferase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Glutamine + H2O + 5_Phospho_alpha_D_ribose_1_diphosphate -> L_Glutamate + Diphosphate + 5_Phospho_beta_D_ribosylamine b2312 Reaction Name: glutamate racemase Estimated Flux: -2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Glutamate <=> L_Glutamate b3967 Reaction Name: glyoxalate carboligase Estimated Flux: 1.609463e-026 mmol gDW- 1 h- 1 Reaction Formula: 2.000000 Glyoxylate + H -> 2_Hydroxy_3_oxopropanoate + CO2 b0507 Reaction Name: glycerate kinase Estimated Flux: 1.609308e-026 mmol gDW- 1 h- 1 Reaction Formula: ATP + R__Glycerate -> 3_Phospho_D_glycerate + ADP + H ( b0514 or b3124 ) Reaction Name: Glycolate oxidase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: 2_Demethylmenaquinone_8 + Glycolate -> 2_Demethylmenaquinol_8 + Glyoxylate ( b2978 and b2979 ) Reaction Name: glycerol transport via channel Estimated Flux: 8.673617e-019 mmol gDW- 1 h- 1 Reaction Formula: Glycerol <=> Glycerol b3927 Reaction Name: glycerol kinase Estimated Flux: 6.529458e-003 mmol gDW- 1 h- 1 Reaction Formula: ATP + Glycerol -> ADP + Glycerol_3_phosphate + H b3926 Reaction Name: D glycero D manno hepose 1 phosphate adenyltransferase Estimated Flux: 2.551044e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + D_Glycero_D_manno_heptose_1_phosphate + H -> ADP_D_glycero_D_manno_heptose + Diphosphate b3052 Reaction Name: D glycero D manno heptose 7 phosphate kinase Estimated Flux: 2.551044e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + D_Glycero_D_manno_heptose_7_phosphate -> ADP + D_Glycero_D_manno_heptose_1_7_bisphosphate + H b3052 Reaction Name: D glycero D manno heptose 1 7 bisphosphate phosphatase Estimated Flux: 2.551044e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Glycero_D_manno_heptose_1_7_bisphosphate + H2O -> D_Glycero_D_manno_heptose_1_phosphate + Phosphate b0200 Reaction Name: GMP synthase Estimated Flux: 2.818398e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + L_Glutamine + H2O + Xanthosine_5__phosphate -> AMP + L_Glutamate + GMP + 2.000000 H + Diphosphate b2507 Reaction Name: phosphogluconate dehydrogenase Estimated Flux: 6.672975e+000 mmol gDW- 1 h- 1 Reaction Formula: 6_Phospho_D_gluconate + Nicotinamide_adenine_dinucleotide_phosphate -> CO2 + Nicotinamide_adenine_dinucleotide_phosphate___reduced + D_Ribulose_5_phosphate b2029 Reaction Name: Glycerophosphodiester phosphodiesterase Glycerophosphoethanolamine Estimated Flux: 6.621968e-029 mmol gDW- 1 h- 1 Reaction Formula: sn_Glycero_3_phosphoethanolamine + H2O -> Ethanolamine + Glycerol_3_phosphate + H b2239 Reaction Name: Glycerophosphodiester phosphodiesterase Glycerophosphoglycerol Estimated Flux: 1.838699e-028 mmol gDW- 1 h- 1 Reaction Formula: Glycerophosphoglycerol + H2O -> Glycerol_3_phosphate + Glycerol + H b2239 Reaction Name: geranyltranstransferase Estimated Flux: -2.014782e-018 mmol gDW- 1 h- 1 Reaction Formula: Geranyl_diphosphate + Isopentenyl_diphosphate -> Farnesyl_diphosphate + Diphosphate b0421 Reaction Name: guanosine kinase Estimated Flux: 5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + Guanosine -> ADP + GMP + H b0477 Reaction Name: GTP cyclohydrolase II 25drapp Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: GTP + 3.000000 H2O -> 2_5_Diamino_6__ribosylamino__4__3H__pyrimidinone_5__phosphate + Formate + 2.000000 H + Diphosphate b1277 Reaction Name: GTP cyclohydrolase I Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: GTP + H2O -> 2_Amino_4_hydroxy_6__erythro_1_2_3_trihydroxypropyl_dihydropteridine_triphosphate + Formate b2153 Reaction Name: H2O transport via diffusion Estimated Flux: -4.345336e+001 mmol gDW- 1 h- 1 Reaction Formula: H2O <=> H2O Reaction Name: Hydroxybenzoate octaprenyltransferase Estimated Flux: -2.646493e-028 mmol gDW- 1 h- 1 Reaction Formula: 4_Hydroxybenzoate + all_trans_Octaprenyl_diphosphate -> 3_Octaprenyl_4_hydroxybenzoate + Diphosphate b4040 Reaction Name: HCO3 equilibration reaction Estimated Flux: 2.819001e+000 mmol gDW- 1 h- 1 Reaction Formula: CO2 + H2O <=> H + Bicarbonate ( b0339 or b0126 ) Reaction Name: hexokinase D glucoseATP Estimated Flux: -2.471670e-025 mmol gDW- 1 h- 1 Reaction Formula: ATP + D_Glucose -> ADP + D_Glucose_6_phosphate + H b2388 Reaction Name: histidinol dehydrogenase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + L_Histidinol + 2.000000 Nicotinamide_adenine_dinucleotide -> 3.000000 H + L_Histidine + 2.000000 Nicotinamide_adenine_dinucleotide___reduced b2020 Reaction Name: histidinol phosphatase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + L_Histidinol_phosphate -> L_Histidinol + Phosphate b2022 Reaction Name: L histidine reversible transport via proton symport Estimated Flux: -1.709352e-026 mmol gDW- 1 h- 1 Reaction Formula: H + L_Histidine <=> H + L_Histidine b0112 Reaction Name: 6 hydroxymethyl dihydropterin pyrophosphokinase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: 6_hydroxymethyl_dihydropterin + ATP -> 6_hydroxymethyl_dihydropterin_pyrophosphate + AMP + H b0142 Reaction Name: homoserine dehydrogenase NADPH Estimated Flux: -1.477986e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Homoserine + Nicotinamide_adenine_dinucleotide_phosphate <=> L_Aspartate_4_semialdehyde + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced ( b3940 or b0002 ) Reaction Name: homoserine O succinyltransferase Estimated Flux: 1.477986e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Homoserine + Succinyl_CoA -> Coenzyme_A + O_Succinyl_L_homoserine b4013 Reaction Name: histidinol phosphate transaminase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: L_Glutamate + 3__Imidazol_4_yl__2_oxopropyl_phosphate -> 2_Oxoglutarate + L_Histidinol_phosphate b2021 Reaction Name: Hypoxanthine transport Estimated Flux: -2.388090e-026 mmol gDW- 1 h- 1 Reaction Formula: Hypoxanthine <=> Hypoxanthine Reaction Name: isocitrate dehydrogenase NADP Estimated Flux: 3.312211e+000 mmol gDW- 1 h- 1 Reaction Formula: Isocitrate + Nicotinamide_adenine_dinucleotide_phosphate <=> 2_Oxoglutarate + CO2 + Nicotinamide_adenine_dinucleotide_phosphate___reduced b1136 Reaction Name: Isochorismate Synthase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: chorismate -> Isochorismate ( b2265 or b0593 ) Reaction Name: Imidazole glycerol 3 phosphate synthase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: L_Glutamine + 5__5_phospho_1_deoxyribulos_1_ylamino_methylideneamino_1__5_phosphoribosyl_imidazole_4_carboxamide -> 5_Amino_1__5_Phospho_D_ribosyl_imidazole_4_carboxamide + D_erythro_1__Imidazol_4_yl_glycerol_3_phosphate + L_Glutamate + H ( b2023 and b2025 ) Reaction Name: imidazoleglycerol phosphate dehydratase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: D_erythro_1__Imidazol_4_yl_glycerol_3_phosphate -> H2O + 3__Imidazol_4_yl__2_oxopropyl_phosphate b2022 Reaction Name: indole 3 glycerol phosphate synthase Estimated Flux: 5.466523e-002 mmol gDW- 1 h- 1 Reaction Formula: 1__2_Carboxyphenylamino__1_deoxy_D_ribulose_5_phosphate + H -> C___3_Indolyl__glycerol_3_phosphate + CO2 + H2O b1262 Reaction Name: isoleucine transaminase Estimated Flux: -2.794001e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + L_Isoleucine <=> S__3_Methyl_2_oxopentanoate + L_Glutamate b3770 Reaction Name: L isoleucine reversible transport via proton symport Estimated Flux: -5.462469e-028 mmol gDW- 1 h- 1 Reaction Formula: H + L_Isoleucine <=> H + L_Isoleucine b0401 Reaction Name: IMP cyclohydrolase Estimated Flux: -5.749051e-001 mmol gDW- 1 h- 1 Reaction Formula: H2O + IMP <=> 5_Formamido_1__5_phospho_D_ribosyl_imidazole_4_carboxamide b4006 Reaction Name: IMP dehydrogenase Estimated Flux: 2.818398e-001 mmol gDW- 1 h- 1 Reaction Formula: H2O + IMP + Nicotinamide_adenine_dinucleotide -> H + Nicotinamide_adenine_dinucleotide___reduced + Xanthosine_5__phosphate b2508 Reaction Name: insosine kinase Estimated Flux: -1.050248e-017 mmol gDW- 1 h- 1 Reaction Formula: ATP + Inosine -> ADP + H + IMP b0477 Reaction Name: inosine transport in via proton symport Estimated Flux: 1.000000e+003 mmol gDW- 1 h- 1 Reaction Formula: H + Inosine -> H + Inosine b2964 Reaction Name: inosine transport in via proton symport reversible Estimated Flux: -1000 mmol gDW- 1 h- 1 Reaction Formula: H + Inosine <=> H + Inosine b2406 Reaction Name: isopentenyl diphosphate D isomerase Estimated Flux: -2.014782e-018 mmol gDW- 1 h- 1 Reaction Formula: Isopentenyl_diphosphate -> Dimethylallyl_diphosphate b2889 Reaction Name: 3 isopropylmalate dehydrogenase Estimated Flux: 4.332726e-001 mmol gDW- 1 h- 1 Reaction Formula: 3_Carboxy_2_hydroxy_4_methylpentanoate + Nicotinamide_adenine_dinucleotide -> 3_Carboxy_4_methyl_2_oxopentanoate + H + Nicotinamide_adenine_dinucleotide___reduced b0073 Reaction Name: 3 isopropylmalate dehydratase Estimated Flux: -4.332726e-001 mmol gDW- 1 h- 1 Reaction Formula: 3_Carboxy_2_hydroxy_4_methylpentanoate <=> 2_Isopropylmaleate + H2O ( b0071 and b0072 ) Reaction Name: 2 isopropylmalate hydratase Estimated Flux: -4.332726e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Isopropylmaleate + H2O <=> 3_Carboxy_3_hydroxy_4_methylpentanoate ( b0071 and b0072 ) Reaction Name: 2 isopropylmalate synthase Estimated Flux: 4.332726e-001 mmol gDW- 1 h- 1 Reaction Formula: 3_Methyl_2_oxobutanoate + Acetyl_CoA + H2O -> 3_Carboxy_3_hydroxy_4_methylpentanoate + Coenzyme_A + H b0074 Reaction Name: acetohydroxy acid isomeroreductase Estimated Flux: 8.402845e-001 mmol gDW- 1 h- 1 Reaction Formula: S__2_Acetolactate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> R__2_3_Dihydroxy_3_methylbutanoate + Nicotinamide_adenine_dinucleotide_phosphate b3774 Reaction Name: ketol acid reductoisomerase 2 Aceto 2 hydroxybutanoate Estimated Flux: 2.794001e-001 mmol gDW- 1 h- 1 Reaction Formula: S__2_Aceto_2_hydroxybutanoate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> R__2_3_Dihydroxy_3_methylpentanoate + Nicotinamide_adenine_dinucleotide_phosphate b3774 Reaction Name: beta ketoacyl ACP synthase 2 Estimated Flux: 3.252581e-001 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + H + Malonyl_acyl_carrier_protein -> Acetoacetyl_ACP + CO2 + Coenzyme_A b1091 Reaction Name: 3 hydroxy myristoyl ACP synthesis Estimated Flux: 3.401392e-002 mmol gDW- 1 h- 1 Reaction Formula: Dodecanoyl_ACP__n_C120ACP_ + 2.000000 H + Malonyl_acyl_carrier_protein + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> R__3_Hydroxytetradecanoyl_acyl_carrier_protein + acyl_carrier_protein + CO2 + Nicotinamide_adenine_dinucleotide_phosphate ( ( b2323 and b1093 ) or ( b1095 and b1093 ) ) Reaction Name: 3 deoxy manno octulosonate cytidylyltransferase Estimated Flux: 4.251740e-002 mmol gDW- 1 h- 1 Reaction Formula: CTP + 3_Deoxy_D_manno_2_octulosonate -> CMP_3_deoxy_D_manno_octulosonate + Diphosphate b0918 Reaction Name: 3 deoxy manno octulosonate 8 phosphatase Estimated Flux: 4.251740e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + 3_Deoxy_D_manno_octulosonate_8_phosphate -> 3_Deoxy_D_manno_2_octulosonate + Phosphate Reaction Name: 3 deoxy D manno octulosonic acid 8 phosphate synthase Estimated Flux: 4.251740e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Arabinose_5_phosphate + H2O + Phosphoenolpyruvate -> 3_Deoxy_D_manno_octulosonate_8_phosphate + Phosphate b1215 Reaction Name: D lactate dehydrogenase Estimated Flux: -4.753036e-024 mmol gDW- 1 h- 1 Reaction Formula: D_Lactate + Nicotinamide_adenine_dinucleotide <=> H + Nicotinamide_adenine_dinucleotide___reduced + Pyruvate ( b2133 or b1380 ) Reaction Name: leucine transaminase irreversible Estimated Flux: 4.332726e-001 mmol gDW- 1 h- 1 Reaction Formula: 4_Methyl_2_oxopentanoate + L_Glutamate -> 2_Oxoglutarate + L_Leucine ( b3770 or b4054 ) Reaction Name: Lipid A disaccaride synthase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: 2_3_Bis_3_hydroxytetradecanoyl__beta_D_glucosaminyl_1_phosphate + UDP_2_3_bis_3_hydroxytetradecanoyl_glucosamine -> H + Lipid_A_Disaccharide + UDP b0182 Reaction Name: Lysophospholipase L acyl glycerophosphoglycerol Estimated Flux: 1.822455e-028 mmol gDW- 1 h- 1 Reaction Formula: 0.020000 acyl_glycerophosphoglycerol___Ecoli_ + H2O -> Glycerophosphoglycerol + H + 0.360000 Hexadecanoate__n_C160_ + 0.070000 Hexadecenoate__n_C161_ + 0.500000 octadecenoate__n_C181_ + 0.020000 tetradecanoate__n_C140_ + 0.050000 tetradecenoate__n_C141_ b3825 Reaction Name: Lysophospholipase L acyl glycerophosphoethanolamine Estimated Flux: 6.621968e-029 mmol gDW- 1 h- 1 Reaction Formula: 0.020000 acyl_glycerophosphoethanolamine___Ecoli_ + H2O -> sn_Glycero_3_phosphoethanolamine + H + 0.360000 Hexadecanoate__n_C160_ + 0.070000 Hexadecenoate__n_C161_ + 0.500000 octadecenoate__n_C181_ + 0.020000 tetradecanoate__n_C140_ + 0.050000 tetradecenoate__n_C141_ b3825 Reaction Name: Lipopolysaccharide synthesis Ecoli Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: 3.000000 ADP_L_glycero_D_manno_heptose + 2.000000 CDPethanolamine + 3.000000 CMP_3_deoxy_D_manno_octulosonate + KDO_2__lipid__A_ + 2.000000 UDPglucose -> 3.000000 ADP + 2.000000 CDP + 3.000000 CMP + 10.000000 H + lipopolysaccharide__Ecoli_ + 2.000000 UDP ( b3621 and b3620 and b3631 and b3627 and b3626 and b3622 ) Reaction Name: malate synthase Estimated Flux: 5.061595e-002 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + Glyoxylate + H2O -> Coenzyme_A + H + L_Malate ( b4014 or b2976 ) Reaction Name: Malonyl CoA ACP transacylase Estimated Flux: 2.335204e+000 mmol gDW- 1 h- 1 Reaction Formula: acyl_carrier_protein + Malonyl_CoA <=> Coenzyme_A + Malonyl_acyl_carrier_protein b1092 Reaction Name: malate dehydrogenase Estimated Flux: 3.299866e+000 mmol gDW- 1 h- 1 Reaction Formula: L_Malate + Nicotinamide_adenine_dinucleotide <=> H + Nicotinamide_adenine_dinucleotide___reduced + Oxaloacetate b3236 Reaction Name: 5 Methylthio 5 deoxy D ribulose 1 phosphate dehydratase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: 5_Methylthio_5_deoxy_D_ribulose_1_phosphate -> 2_3_diketo_5_methylthio_1_phosphopentane + H2O Reaction Name: methionine adenosyltransferase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: ATP + H2O + L_Methionine -> S_Adenosyl_L_methionine + Phosphate + Diphosphate b2942 Reaction Name: methionine synthase Estimated Flux: 1.477986e-001 mmol gDW- 1 h- 1 Reaction Formula: 5_Methyltetrahydrofolate + L_Homocysteine -> L_Methionine + 5_6_7_8_Tetrahydrofolate ( b4019 or b3829 ) Reaction Name: Methylmalonyl CoA decarboxylase Estimated Flux: 1.669848e-013 mmol gDW- 1 h- 1 Reaction Formula: H + S__Methylmalonyl_CoA -> CO2 + Propanoyl_CoA b2919 Reaction Name: methylmalonyl CoA epimerase Estimated Flux: 1.669848e-013 mmol gDW- 1 h- 1 Reaction Formula: R__Methylmalonyl_CoA <=> S__Methylmalonyl_CoA Reaction Name: Methylmalonyl CoA mutase Estimated Flux: 1.669848e-013 mmol gDW- 1 h- 1 Reaction Formula: Succinyl_CoA -> R__Methylmalonyl_CoA b2917 Reaction Name: 3 deoxy D manno octulosonic acid transferase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: CMP_3_deoxy_D_manno_octulosonate + 2_3_2_3__Tetrakis_beta_hydroxymyristoyl__D_glucosaminyl_1_6_beta_D_glucosamine_1_4__bisphosphate -> CMP + H + KDO_lipid_IV_A_ b3633 Reaction Name: 3 deoxy D manno octulosonic acid transferase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: CMP_3_deoxy_D_manno_octulosonate + KDO_lipid_IV_A_ -> CMP + H + KDO_2__lipid_IV_A_ b3633 Reaction Name: 3 methyl 2 oxobutanoate hydroxymethyltransferase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: 3_Methyl_2_oxobutanoate + H2O + 5_10_Methylenetetrahydrofolate -> 2_Dehydropantoate + 5_6_7_8_Tetrahydrofolate b0134 Reaction Name: methylthioadenosine nucleosidase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: 5_Methylthioadenosine + H2O -> 5_Methylthio_D_ribose + Adenine b0159 Reaction Name: methenyltetrahydrofolate cyclohydrolase Estimated Flux: 1.372856e+000 mmol gDW- 1 h- 1 Reaction Formula: H2O + 5_10_Methenyltetrahydrofolate <=> 10_Formyltetrahydrofolate b0529 Reaction Name: methylenetetrahydrofolate dehydrogenase NADP Estimated Flux: 1.372856e+000 mmol gDW- 1 h- 1 Reaction Formula: 5_10_Methylenetetrahydrofolate + Nicotinamide_adenine_dinucleotide_phosphate <=> H + 5_10_Methenyltetrahydrofolate + Nicotinamide_adenine_dinucleotide_phosphate___reduced b0529 Reaction Name: 5 10 methylenetetrahydrofolate reductase NADH Estimated Flux: 1.984145e-001 mmol gDW- 1 h- 1 Reaction Formula: H + 5_10_Methylenetetrahydrofolate + Nicotinamide_adenine_dinucleotide___reduced -> 5_Methyltetrahydrofolate + Nicotinamide_adenine_dinucleotide b3941 Reaction Name: 5 methylthioribose 1 phosphate isomerase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: 5_Methylthio_5_deoxy_D_ribose_1_phosphate <=> 5_Methylthio_5_deoxy_D_ribulose_1_phosphate Reaction Name: 5 methylthioribose kinase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: 5_Methylthio_D_ribose + ATP -> 5_Methylthio_5_deoxy_D_ribose_1_phosphate + ADP + H Reaction Name: NADH dehydrogenase ubiquinone 8 35 protons Estimated Flux: 3.706782e+001 mmol gDW- 1 h- 1 Reaction Formula: 4.500000 H + Nicotinamide_adenine_dinucleotide___reduced + Ubiquinone_8 -> 3.500000 H + Nicotinamide_adenine_dinucleotide + Ubiquinol_8 ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 ) Reaction Name: NAD kinase Estimated Flux: 5.365291e-004 mmol gDW- 1 h- 1 Reaction Formula: ATP + Nicotinamide_adenine_dinucleotide -> ADP + H + Nicotinamide_adenine_dinucleotide_phosphate b2615 Reaction Name: NAD synthase nh3 Estimated Flux: 2.763631e-003 mmol gDW- 1 h- 1 Reaction Formula: ATP + Deamino_NAD + Ammonium -> AMP + H + Nicotinamide_adenine_dinucleotide + Diphosphate b1740 Reaction Name: sodium proton antiporter HNA is 11 Estimated Flux: 1000 mmol gDW- 1 h- 1 Reaction Formula: H + Sodium <=> H + Sodium b1216 Reaction Name: nucleoside diphosphate kinase ATPGDP Estimated Flux: -9.968769e+002 mmol gDW- 1 h- 1 Reaction Formula: ATP + GDP <=> ADP + GTP b2518 Reaction Name: nucleoside diphosphate kinase ATPUDP Estimated Flux: 3.838714e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + UDP <=> ADP + UTP b2518 Reaction Name: nucleoside diphosphate kinase ATPCDP Estimated Flux: 1.967027e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + CDP <=> ADP + CTP b2518 Reaction Name: nucleoside diphosphate kinase ATPdTDP Estimated Flux: 2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + dTDP <=> ADP + dTTP b2518 Reaction Name: nucleoside diphosphate kinase ATPdGDP Estimated Flux: 2.571290e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + dGDP <=> ADP + dGTP b2518 Reaction Name: nucleoside diphosphate kinase ATPdADP Estimated Flux: 2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + dADP <=> ADP + dATP b2518 Reaction Name: ammonia reversible transport Estimated Flux: 1.081609e+001 mmol gDW- 1 h- 1 Reaction Formula: Ammonium <=> Ammonium b0451 Reaction Name: nicotinamide nucleotide adenylyltransferase Estimated Flux: 1.451938e-026 mmol gDW- 1 h- 1 Reaction Formula: ATP + H + NMN -> Nicotinamide_adenine_dinucleotide + Diphosphate b0639 Reaction Name: nicotinate nucleotide adenylyltransferase Estimated Flux: 2.763631e-003 mmol gDW- 1 h- 1 Reaction Formula: ATP + H + Nicotinate_D_ribonucleotide -> Deamino_NAD + Diphosphate b0639 Reaction Name: nicotinate nucleotide diphosphorylase carboxylating Estimated Flux: 2.763631e-003 mmol gDW- 1 h- 1 Reaction Formula: 2.000000 H + 5_Phospho_alpha_D_ribose_1_diphosphate + Quinolinate -> CO2 + Nicotinate_D_ribonucleotide + Diphosphate b0109 Reaction Name: naphthoate synthase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: O_Succinylbenzoyl_CoA -> Coenzyme_A + 1_4_Dihydroxy_2_naphthoate b2262 Reaction Name: 5 nucleotidase dUMP Estimated Flux: -5.903489e-028 mmol gDW- 1 h- 1 Reaction Formula: dUMP + H2O -> Deoxyuridine + Phosphate b0480 Reaction Name: 5 nucleotidase dGMP Estimated Flux: 5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: dGMP + H2O -> Deoxyguanosine + Phosphate b0480 Reaction Name: o2 transport diffusion Estimated Flux: 2.000000e+001 mmol gDW- 1 h- 1 Reaction Formula: O2 <=> O2 Reaction Name: ornithine carbamoyltransferase Estimated Flux: 2.844617e-001 mmol gDW- 1 h- 1 Reaction Formula: Carbamoyl_phosphate + Ornithine <=> L_Citrulline + H + Phosphate ( b4254 or b0273 ) Reaction Name: Octaprenyl pyrophosphate synthase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: Farnesyl_diphosphate + 5.000000 Isopentenyl_diphosphate -> all_trans_Octaprenyl_diphosphate + 5.000000 Diphosphate b3187 Reaction Name: 2 Octaprenyl 6 methoxy benzoquinol methylase Estimated Flux: 3.154076e-028 mmol gDW- 1 h- 1 Reaction Formula: 2_Octaprenyl_6_methoxy_1_4_benzoquinol + S_Adenosyl_L_methionine -> 2_Octaprenyl_3_methyl_6_methoxy__1_4_benzoquinol + S_Adenosyl_L_homocysteine + H b3833 Reaction Name: 2 Oxo 4 methyl 3 carboxypentanoate decarboxylation Estimated Flux: 4.332726e-001 mmol gDW- 1 h- 1 Reaction Formula: 3_Carboxy_4_methyl_2_oxopentanoate + H -> 4_Methyl_2_oxopentanoate + CO2 b0073 Reaction Name: 2 Octaprenyl 3 methyl 6 methoxy 1 4 benzoquinol hydroxylase Estimated Flux: 3.154844e-028 mmol gDW- 1 h- 1 Reaction Formula: 2_Octaprenyl_3_methyl_6_methoxy__1_4_benzoquinol + 0.500000 O2 -> 2_Octaprenyl_3_methyl_5_hydroxy_6_methoxy_1_4_benzoquinol b0662 Reaction Name: orotidine 5 phosphate decarboxylase Estimated Flux: 3.189817e-001 mmol gDW- 1 h- 1 Reaction Formula: H + Orotidine_5__phosphate -> CO2 + UMP b1281 Reaction Name: Octaprenyl hydroxybenzoate decarboxylase Estimated Flux: -2.646519e-028 mmol gDW- 1 h- 1 Reaction Formula: 3_Octaprenyl_4_hydroxybenzoate + H -> 2_Octaprenylphenol + CO2 ( b3843 or b2311 ) Reaction Name: Ornithine Decarboxylase Estimated Flux: 4.251740e-002 mmol gDW- 1 h- 1 Reaction Formula: H + Ornithine -> CO2 + Putrescine ( b2965 or b0693 ) Reaction Name: orotate phosphoribosyltransferase Estimated Flux: -3.189817e-001 mmol gDW- 1 h- 1 Reaction Formula: Orotidine_5__phosphate + Diphosphate <=> Orotate + 5_Phospho_alpha_D_ribose_1_diphosphate b3642 Reaction Name: 2 oxoglutarate decarboxylase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + H + Thiamine_diphosphate -> CO2 + Succinate_semialdehyde_thiamin_diphosphate_anion b2264 Reaction Name: pyrroline 5 carboxylate reductase Estimated Flux: 2.125870e-001 mmol gDW- 1 h- 1 Reaction Formula: 1_Pyrroline_5_carboxylate + 2.000000 H + Nicotinamide_adenine_dinucleotide_phosphate___reduced -> Nicotinamide_adenine_dinucleotide_phosphate + L_Proline b0386 Reaction Name: pantothenate synthase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: beta_Alanine + ATP + R__Pantoate -> AMP + H + R__Pantothenate + Diphosphate b0133 Reaction Name: phospho N acetylmuramoyl pentapeptide transferase meso 2 6 diaminopimelate Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: Undecaprenyl_phosphate + UDP_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine -> Undecaprenyl_diphospho_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine + UMP b0087 Reaction Name: phosphoadenylyl sulfate reductase thioredoxin Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: 3__Phosphoadenylyl_sulfate + Reduced_thioredoxin -> 2.000000 H + Adenosine_3__5__bisphosphate + Sulfite + Oxidized_thioredoxin b2762 Reaction Name: Phosphatidic acid synthase Ecoli Estimated Flux: 1.371186e-001 mmol gDW- 1 h- 1 Reaction Formula: Glycerol_3_phosphate + 0.140000 cis_hexadec_9_enoyl_acyl_carrier_protein__n_C161_ + 0.040000 Myristoyl_ACP__n_C140ACP_ + cis_octadec_11_enoyl_acyl_carrier_protein__n_C181_ + 0.720000 Palmitoyl_ACP__n_C160ACP_ + 0.100000 cis_tetradec_7_enoyl_acyl_carrier_protein__n_C141_ -> 2.000000 acyl_carrier_protein + 0.020000 phosphatidate___Ecoli_ ( b4041 and b3018 ) Reaction Name: pyruvate dehydrogenase Estimated Flux: 1.020920e+001 mmol gDW- 1 h- 1 Reaction Formula: Coenzyme_A + Nicotinamide_adenine_dinucleotide + Pyruvate -> Acetyl_CoA + CO2 + Nicotinamide_adenine_dinucleotide___reduced ( b0114 and b0115 and b0116 ) Reaction Name: ethanolamine phosphotransferase Estimated Flux: 1.700696e-002 mmol gDW- 1 h- 1 Reaction Formula: CMP + H + 0.020000 Phosphatidylethanolamine__ecoli_ <=> 0.020000 1_2_Diacylglycerol___Ecoli_ + CDPethanolamine Reaction Name: phosphofructokinase Estimated Flux: 8.237940e+000 mmol gDW- 1 h- 1 Reaction Formula: ATP + D_Fructose_6_phosphate -> ADP + D_Fructose_1_6_bisphosphate + H ( b3916 or b1723 ) Reaction Name: phosphoglucosamine mutase Estimated Flux: -7.288697e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Glucosamine_1_phosphate <=> D_Glucosamine_6_phosphate b3176 Reaction Name: phosphoglycerate dehydrogenase Estimated Flux: 2.157371e+000 mmol gDW- 1 h- 1 Reaction Formula: 3_Phospho_D_glycerate + Nicotinamide_adenine_dinucleotide -> 3_Phosphohydroxypyruvate + H + Nicotinamide_adenine_dinucleotide___reduced b2913 Reaction Name: glucose 6 phosphate isomerase Estimated Flux: 5.051084e+000 mmol gDW- 1 h- 1 Reaction Formula: D_Glucose_6_phosphate <=> D_Fructose_6_phosphate b4025 Reaction Name: phosphoglycerate kinase Estimated Flux: -1.833137e+001 mmol gDW- 1 h- 1 Reaction Formula: 3_Phospho_D_glycerate + ATP <=> 3_Phospho_D_glyceroyl_phosphate + ADP b2926 Reaction Name: 6 phosphogluconolactonase Estimated Flux: 6.672975e+000 mmol gDW- 1 h- 1 Reaction Formula: 6_phospho_D_glucono_1_5_lactone + H2O -> 6_Phospho_D_gluconate + H Reaction Name: phosphoglycerate mutase Estimated Flux: -1.617399e+001 mmol gDW- 1 h- 1 Reaction Formula: D_Glycerate_2_phosphate <=> 3_Phospho_D_glycerate ( b4395 or b0755 or b3612 ) Reaction Name: phosphoglucomutase Estimated Flux: -1.759411e-001 mmol gDW- 1 h- 1 Reaction Formula: D_Glucose_1_phosphate <=> D_Glucose_6_phosphate ( b0688 or b2690 ) Reaction Name: Phosphatidylglycerol phosphate phosphatase Ecoli Estimated Flux: 3.654472e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + 0.020000 Phosphatidylglycerophosphate__Ecoli_ -> 0.020000 Phosphatidylglycerol__Ecoli_ + Phosphate ( b0418 or b1278 ) Reaction Name: Phosphatidylglycerol synthase Ecoli Estimated Flux: 3.654472e-002 mmol gDW- 1 h- 1 Reaction Formula: 0.020000 CDPdiacylglycerol__E_coli_ + Glycerol_3_phosphate <=> CMP + H + 0.020000 Phosphatidylglycerophosphate__Ecoli_ b1912 Reaction Name: phenylalanine transaminase Estimated Flux: -1.781682e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + L_Phenylalanine <=> L_Glutamate + Phenylpyruvate ( b4054 or b3770 or b0928 ) Reaction Name: phosphate reversible transport via symport Estimated Flux: 9.228675e-001 mmol gDW- 1 h- 1 Reaction Formula: H + Phosphate <=> H + Phosphate ( b3493 or b2987 ) Reaction Name: Phosphlipase A phosphatidylethanolamine Estimated Flux: 6.621968e-029 mmol gDW- 1 h- 1 Reaction Formula: H2O + 0.020000 Phosphatidylethanolamine__ecoli_ -> 0.020000 acyl_glycerophosphoethanolamine___Ecoli_ + H + 0.360000 Hexadecanoate__n_C160_ + 0.070000 Hexadecenoate__n_C161_ + 0.500000 octadecenoate__n_C181_ + 0.020000 tetradecanoate__n_C140_ + 0.050000 tetradecenoate__n_C141_ b3821 Reaction Name: pyrimidine phosphatase Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: 5_Amino_6__5__phosphoribitylamino_uracil + H2O -> 4__1_D_Ribitylamino__5_aminouracil + Phosphate Reaction Name: pantothenate kinase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: ATP + R__Pantothenate -> D_4__Phosphopantothenate + ADP + H b3974 Reaction Name: inorganic diphosphatase Estimated Flux: 3.400699e+000 mmol gDW- 1 h- 1 Reaction Formula: H2O + Diphosphate -> H + 2.000000 Phosphate b4226 Reaction Name: Propionate kinase Estimated Flux: 1.682172e+000 mmol gDW- 1 h- 1 Reaction Formula: ADP + Propanoyl_phosphate <=> ATP + Propionate__n_C30_ b3115 Reaction Name: phosphoenolpyruvate carboxylase Estimated Flux: 2.364870e+000 mmol gDW- 1 h- 1 Reaction Formula: CO2 + H2O + Phosphoenolpyruvate -> H + Oxaloacetate + Phosphate b3956 Reaction Name: phosphopantothenoylcysteine decarboxylase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: N___R__4_Phosphopantothenoyl__L_cysteine + H -> CO2 + Pantetheine_4__phosphate Reaction Name: Propanoyl CoA succinate CoA transferase Estimated Flux: 9.983178e+002 mmol gDW- 1 h- 1 Reaction Formula: Propanoyl_CoA + Succinate -> Propionate__n_C30_ + Succinyl_CoA b2920 Reaction Name: phosphopentomutase Estimated Flux: -5.304552e-001 mmol gDW- 1 h- 1 Reaction Formula: alpha_D_Ribose_1_phosphate <=> alpha_D_Ribose_5_phosphate ( b4383 or b3380 ) Reaction Name: phosphopentomutase 2 deoxyribose Estimated Flux: 5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Deoxy_D_ribose_1_phosphate <=> 2_Deoxy_D_ribose_5_phosphate b4383 Reaction Name: phosphopantothenate cysteine ligase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: D_4__Phosphopantothenate + CTP + L_Cysteine -> N___R__4_Phosphopantothenoyl__L_cysteine + CMP + H + Diphosphate Reaction Name: prephenate dehydrogenase Estimated Flux: 1.326138e-001 mmol gDW- 1 h- 1 Reaction Formula: Nicotinamide_adenine_dinucleotide + Prephenate -> 3__4_Hydroxyphenyl_pyruvate + CO2 + Nicotinamide_adenine_dinucleotide___reduced b2600 Reaction Name: prephenate dehydratase Estimated Flux: 1.781682e-001 mmol gDW- 1 h- 1 Reaction Formula: H + Prephenate -> CO2 + H2O + Phenylpyruvate b2599 Reaction Name: Peptidoglycan subunit synthesis Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: Undecaprenyl_diphospho_N_acetylmuramoyl__N_acetylglucosamine__L_ala_D_glu_meso_2_6_diaminopimeloyl_D_ala_D_ala -> H + Peptidoglycan_subunit_of_Escherichia_coli + Undecaprenyl_diphosphate Reaction Name: phosphoribosylglycinamide synthase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + Glycine + 5_Phospho_beta_D_ribosylamine <=> ADP + N1__5_Phospho_D_ribosyl_glycinamide + H + Phosphate b4005 Reaction Name: phosphoribosylaminoimidazole synthase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + 2__Formamido__N1__5_phospho_D_ribosyl_acetamidine -> ADP + 5_amino_1__5_phospho_D_ribosyl_imidazole + 2.000000 H + Phosphate b2499 Reaction Name: phosphoribosylanthranilate isomerase irreversible Estimated Flux: 5.466523e-002 mmol gDW- 1 h- 1 Reaction Formula: N__5_Phospho_D_ribosyl_anthranilate -> 1__2_Carboxyphenylamino__1_deoxy_D_ribulose_5_phosphate b1262 Reaction Name: phosphoribosyl AMP cyclohydrolase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + 1__5_Phosphoribosyl__AMP -> 1__5_Phosphoribosyl__5__5_phosphoribosylamino_methylideneaminoimidazole_4_carboxamide b2026 Reaction Name: phosphoribosylaminoimidazolesuccinocarboxamide synthase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: 5_amino_1__5_phospho_D_ribosyl_imidazole_4_carboxylate + L_Aspartate + ATP <=> S__2_5_Amino_1__5_phospho_D_ribosyl_imidazole_4_carboxamidosuccinate + ADP + H + Phosphate b2476 Reaction Name: phosphoribosyl ATP pyrophosphatase Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + 1__5_Phosphoribosyl__ATP -> H + Diphosphate + 1__5_Phosphoribosyl__AMP b2026 Reaction Name: phosphoribosylformylglycinamidine synthase Estimated Flux: 4.837964e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + N2_Formyl_N1__5_phospho_D_ribosyl_glycinamide + L_Glutamine + H2O -> ADP + 2__Formamido__N1__5_phospho_D_ribosyl_acetamidine + L_Glutamate + H + Phosphate b2557 Reaction Name: 1 5 phosphoribosyl 5 5 phosphoribosylamino methylideneamino imidazole 4 carboxamide isomerase irreversible Estimated Flux: 9.110872e-002 mmol gDW- 1 h- 1 Reaction Formula: 1__5_Phosphoribosyl__5__5_phosphoribosylamino_methylideneaminoimidazole_4_carboxamide -> 5__5_phospho_1_deoxyribulos_1_ylamino_methylideneamino_1__5_phosphoribosyl_imidazole_4_carboxamide b2024 Reaction Name: L proline reversible transport via proton symport Estimated Flux: -1000 mmol gDW- 1 h- 1 Reaction Formula: H + L_Proline <=> H + L_Proline b4111 Reaction Name: NaProline L symporter Estimated Flux: 1000 mmol gDW- 1 h- 1 Reaction Formula: Sodium + L_Proline -> Sodium + L_Proline b1015 Reaction Name: phosphoribosylpyrophosphate synthetase Estimated Flux: 9.513157e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + alpha_D_Ribose_5_phosphate <=> AMP + H + 5_Phospho_alpha_D_ribose_1_diphosphate b1207 Reaction Name: 3 phosphoshikimate 1 carboxyvinyltransferase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: Phosphoenolpyruvate + Shikimate_5_phosphate <=> 5_O__1_Carboxyvinyl__3_phosphoshikimate + Phosphate b0908 Reaction Name: Phosphatidylserine decarboxylase Ecoli Estimated Flux: 1.149488e-001 mmol gDW- 1 h- 1 Reaction Formula: H + 0.020000 phosphatidylserine__Ecoli_ -> CO2 + 0.020000 Phosphatidylethanolamine__ecoli_ b4160 Reaction Name: phosphoserine transaminase Estimated Flux: 2.157371e+000 mmol gDW- 1 h- 1 Reaction Formula: 3_Phosphohydroxypyruvate + L_Glutamate -> 2_Oxoglutarate + O_Phospho_L_serine b0907 Reaction Name: phosphoserine phosphatase L serine Estimated Flux: 2.157371e+000 mmol gDW- 1 h- 1 Reaction Formula: H2O + O_Phospho_L_serine -> Phosphate + L_Serine b4388 Reaction Name: Phosphatidylserine syntase Ecoli Estimated Flux: 1.175809e-001 mmol gDW- 1 h- 1 Reaction Formula: 0.020000 CDPdiacylglycerol__E_coli_ + L_Serine <=> CMP + H + 0.020000 phosphatidylserine__Ecoli_ b2585 Reaction Name: Phosphate acetyltransferase Estimated Flux: 1.682172e+000 mmol gDW- 1 h- 1 Reaction Formula: Phosphate + Propanoyl_CoA -> Coenzyme_A + Propanoyl_phosphate b2297 Reaction Name: phosphotransacetylase Estimated Flux: 3.116790e+000 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + Phosphate <=> Acetyl_phosphate + Coenzyme_A ( b2297 or b2458 ) Reaction Name: pantetheine phosphate adenylyltransferase Estimated Flux: 5.972682e-005 mmol gDW- 1 h- 1 Reaction Formula: ATP + H + Pantetheine_4__phosphate -> Dephospho_CoA + Diphosphate b3634 Reaction Name: putrescine transport in via proton symport reversible Estimated Flux: -6.839264e-027 mmol gDW- 1 h- 1 Reaction Formula: H + Putrescine <=> H + Putrescine b0692 Reaction Name: purine nucleoside phosphorylase Adenosine Estimated Flux: -7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: Adenosine + Phosphate <=> Adenine + alpha_D_Ribose_1_phosphate ( b2407 or b4384 ) Reaction Name: purine nucleoside phosphorylase Guanosine Estimated Flux: -5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: Guanosine + Phosphate <=> Guanine + alpha_D_Ribose_1_phosphate ( b2407 or b4384 ) Reaction Name: purine nucleoside phosphorylase Deoxyguanosine Estimated Flux: 5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: Deoxyguanosine + Phosphate <=> 2_Deoxy_D_ribose_1_phosphate + Guanine ( b2407 or b4384 ) Reaction Name: purine nucleoside phosphorylase Inosine Estimated Flux: 2.388090e-026 mmol gDW- 1 h- 1 Reaction Formula: Inosine + Phosphate <=> Hypoxanthine + alpha_D_Ribose_1_phosphate ( b2407 or b4384 ) Reaction Name: purine nucleoside phosphorylase Xanthosine Estimated Flux: -2.804196e-028 mmol gDW- 1 h- 1 Reaction Formula: Phosphate + Xanthosine <=> alpha_D_Ribose_1_phosphate + Xanthine ( b2407 or b4384 ) Reaction Name: pyruvate kinase Estimated Flux: 1.006541e+000 mmol gDW- 1 h- 1 Reaction Formula: ADP + H + Phosphoenolpyruvate -> ATP + Pyruvate ( b1854 or b1676 ) Reaction Name: pyrimidine nucleoside phosphorylase uracil Estimated Flux: -8.149470e-027 mmol gDW- 1 h- 1 Reaction Formula: Phosphate + Uridine <=> alpha_D_Ribose_1_phosphate + Uracil b3831 Reaction Name: quinolinate synthase Estimated Flux: 2.763631e-003 mmol gDW- 1 h- 1 Reaction Formula: Dihydroxyacetone_phosphate + Iminoaspartate -> 2.000000 H2O + H + Phosphate + Quinolinate b0750 Reaction Name: riboflavin kinase Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: ATP + Riboflavin -> ADP + FMN + H b0025 Reaction Name: riboflavin synthase Estimated Flux: 2.024638e-005 mmol gDW- 1 h- 1 Reaction Formula: 4__1_D_Ribitylamino__5_aminouracil + 3_4_dihydroxy_2_butanone_4_phosphate -> 6_7_Dimethyl_8__1_D_ribityl_lumazine + 2.000000 H2O + Phosphate b1662 Reaction Name: riboflavin synthase Estimated Flux: 1.012319e-005 mmol gDW- 1 h- 1 Reaction Formula: 2.000000 6_7_Dimethyl_8__1_D_ribityl_lumazine -> 4__1_D_Ribitylamino__5_aminouracil + Riboflavin b0415 Reaction Name: ribonucleoside diphosphate reductase ADP Estimated Flux: 2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: ADP + Reduced_thioredoxin -> dADP + H2O + Oxidized_thioredoxin ( b2234 and b2235 ) Reaction Name: ribonucleoside diphosphate reductase GDP Estimated Flux: 5.490819e-001 mmol gDW- 1 h- 1 Reaction Formula: GDP + Reduced_thioredoxin -> dGDP + H2O + Oxidized_thioredoxin ( b2234 and b2235 ) Reaction Name: ribonucleoside diphosphate reductase UDP Estimated Flux: 2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: Reduced_thioredoxin + UDP -> dUDP + H2O + Oxidized_thioredoxin ( b2234 and b2235 ) Reaction Name: ribonucleoside triphosphate reductase CTP Estimated Flux: 2.571290e-002 mmol gDW- 1 h- 1 Reaction Formula: CTP + Reduced_thioredoxin -> dCTP + H2O + Oxidized_thioredoxin b4238 Reaction Name: ribulose 5 phosphate 3 epimerase Estimated Flux: 3.285253e+000 mmol gDW- 1 h- 1 Reaction Formula: D_Ribulose_5_phosphate <=> D_Xylulose_5_phosphate ( b3386 or b4301 ) Reaction Name: ribose 5 phosphate isomerase Estimated Flux: -3.345184e+000 mmol gDW- 1 h- 1 Reaction Formula: alpha_D_Ribose_5_phosphate <=> D_Ribulose_5_phosphate ( b2914 or b4090 ) Reaction Name: sedoheptulose 7 phosphate isomerase Estimated Flux: 2.551044e-002 mmol gDW- 1 h- 1 Reaction Formula: Sedoheptulose_7_phosphate -> D_Glycero_D_manno_heptose_7_phosphate b0222 Reaction Name: Sulfate adenyltransferase Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + GTP + H2O + Sulfate -> Adenosine_5__phosphosulfate + GDP + Phosphate + Diphosphate ( b2751 and b2752 ) Reaction Name: succinyl diaminopimelate desuccinylase Estimated Flux: 3.579560e-001 mmol gDW- 1 h- 1 Reaction Formula: H2O + N_Succinyl_LL_2_6_diaminoheptanedioate -> LL_2_6_Diaminoheptanedioate + Succinate b2472 Reaction Name: succinyldiaminopimelate transaminase Estimated Flux: -3.579560e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + N_Succinyl_LL_2_6_diaminoheptanedioate <=> L_Glutamate + N_Succinyl_2_L_amino_6_oxoheptanedioate Reaction Name: serine O acetyltransferase Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: Acetyl_CoA + L_Serine <=> O_Acetyl_L_serine + Coenzyme_A b3607 Reaction Name: 2 succinyl 6 hydroxy 2 4 cyclohexadiene 1 carboxylate synthase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: Isochorismate + Succinate_semialdehyde_thiamin_diphosphate_anion -> 2_Succinyl_6_hydroxy_2_4_cyclohexadiene_1_carboxylate + Pyruvate + Thiamine_diphosphate b2264 Reaction Name: shikimate dehydrogenase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: 3_Dehydroshikimate + H + Nicotinamide_adenine_dinucleotide_phosphate___reduced <=> Nicotinamide_adenine_dinucleotide_phosphate + Shikimate ( b3281 or b1692 ) Reaction Name: shikimate kinase Estimated Flux: 4.160631e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + Shikimate -> ADP + H + Shikimate_5_phosphate ( b3390 or b0388 ) Reaction Name: O succinylhomoserine lyase L cysteine Estimated Flux: 1.477986e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Cysteine + O_Succinyl_L_homoserine -> L_Cystathionine + H + Succinate b3939 Reaction Name: spermidine synthase Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: S_Adenosylmethioninamine + Putrescine -> 5_Methylthioadenosine + H + Spermidine b0121 Reaction Name: o succinylbenzoate CoA ligase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: ATP + Coenzyme_A + o_Succinylbenzoate -> AMP + Diphosphate + O_Succinylbenzoyl_CoA b2260 Reaction Name: O succinylbenzoate CoA synthase Estimated Flux: -7.387533e-018 mmol gDW- 1 h- 1 Reaction Formula: 2_Succinyl_6_hydroxy_2_4_cyclohexadiene_1_carboxylate -> H2O + o_Succinylbenzoate b2261 Reaction Name: succinate dehydrogenase Estimated Flux: 2.560287e+000 mmol gDW- 1 h- 1 Reaction Formula: Flavin_adenine_dinucleotide_oxidized + Succinate -> Flavin_adenine_dinucleotide_reduced + Fumarate ( b0721 and b0722 and b0723 and b0724 ) Reaction Name: succinate dehyrdogenase Estimated Flux: 2.560287e+000 mmol gDW- 1 h- 1 Reaction Formula: Flavin_adenine_dinucleotide_reduced + Ubiquinone_8 <=> Flavin_adenine_dinucleotide_oxidized + Ubiquinol_8 ( b0721 and b0722 and b0723 and b0724 ) Reaction Name: succinyl CoA synthetase ADP forming Estimated Flux: -1000 mmol gDW- 1 h- 1 Reaction Formula: ATP + Coenzyme_A + Succinate <=> ADP + Phosphate + Succinyl_CoA ( b0728 and b0729 ) Reaction Name: sulfite reductase NADPH2 Estimated Flux: -2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: 3.000000 H2O + Hydrogen_sulfide + 3.000000 Nicotinamide_adenine_dinucleotide_phosphate <=> 5.000000 H + 3.000000 Nicotinamide_adenine_dinucleotide_phosphate___reduced + Sulfite ( b2763 and b2764 ) Reaction Name: sulfate transport via ABC system Estimated Flux: 2.359301e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + H2O + Sulfate -> ADP + H + Phosphate + Sulfate ( ( b2422 and b2424 and b2423 and b2413 and b3917 ) or ( b2422 and b2425 and b2424 and b2423 ) ) Reaction Name: transaldolase Estimated Flux: 1.837903e+000 mmol gDW- 1 h- 1 Reaction Formula: Glyceraldehyde_3_phosphate + Sedoheptulose_7_phosphate <=> D_Erythrose_4_phosphate + D_Fructose_6_phosphate ( b0008 or b2464 ) Reaction Name: Tetraacyldisaccharide 4 kinase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: ATP + Lipid_A_Disaccharide -> ADP + H + 2_3_2_3__Tetrakis_beta_hydroxymyristoyl__D_glucosaminyl_1_6_beta_D_glucosamine_1_4__bisphosphate b0915 Reaction Name: tetrahydrodipicolinate succinylase Estimated Flux: 3.579560e-001 mmol gDW- 1 h- 1 Reaction Formula: H2O + Succinyl_CoA + 2_3_4_5_Tetrahydrodipicolinate -> Coenzyme_A + N_Succinyl_2_L_amino_6_oxoheptanedioate b0166 Reaction Name: thiamine transport via ABC system Estimated Flux: 5.453350e-034 mmol gDW- 1 h- 1 Reaction Formula: ATP + H2O + Thiamin -> ADP + H + Phosphate + Thiamin ( b0068 and b0067 and b0066 ) Reaction Name: Threonine Aldolase Estimated Flux: -5.233690e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Threonine <=> Acetaldehyde + Glycine ( b0870 or b2551 ) Reaction Name: L threonine deaminase Estimated Flux: 2.794001e-001 mmol gDW- 1 h- 1 Reaction Formula: L_Threonine -> 2_Oxobutanoate + Ammonium ( b3117 or b1814 or b2797 or b3772 ) Reaction Name: transketolase Estimated Flux: 1.863413e+000 mmol gDW- 1 h- 1 Reaction Formula: alpha_D_Ribose_5_phosphate + D_Xylulose_5_phosphate <=> Glyceraldehyde_3_phosphate + Sedoheptulose_7_phosphate ( b2935 or b2465 ) Reaction Name: transketolase Estimated Flux: 1.421840e+000 mmol gDW- 1 h- 1 Reaction Formula: D_Erythrose_4_phosphate + D_Xylulose_5_phosphate <=> D_Fructose_6_phosphate + Glyceraldehyde_3_phosphate ( b2935 or b2465 ) Reaction Name: thymidylate synthase Estimated Flux: 2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: dUMP + 5_10_Methylenetetrahydrofolate -> 7_8_Dihydrofolate + dTMP b2827 Reaction Name: thiamine kinase Estimated Flux: 5.453350e-034 mmol gDW- 1 h- 1 Reaction Formula: ATP + Thiamin <=> ADP + H + Thiamin_monophosphate Reaction Name: thiamine phosphate kinase Estimated Flux: 5.453350e-034 mmol gDW- 1 h- 1 Reaction Formula: ATP + Thiamin_monophosphate <=> ADP + Thiamine_diphosphate b0417 Reaction Name: triose phosphate isomerase Estimated Flux: 8.068042e+000 mmol gDW- 1 h- 1 Reaction Formula: Dihydroxyacetone_phosphate <=> Glyceraldehyde_3_phosphate b3919 Reaction Name: thioredoxin reductase NADPH Estimated Flux: 8.607334e-001 mmol gDW- 1 h- 1 Reaction Formula: H + Nicotinamide_adenine_dinucleotide_phosphate___reduced + Oxidized_thioredoxin -> Nicotinamide_adenine_dinucleotide_phosphate + Reduced_thioredoxin b0888 Reaction Name: Tryptophanase L tryptophan Estimated Flux: -5.466523e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + L_Tryptophan <=> Indole + Ammonium + Pyruvate b3708 Reaction Name: tryptophan synthase indoleglycerol phosphate Estimated Flux: 5.466523e-002 mmol gDW- 1 h- 1 Reaction Formula: C___3_Indolyl__glycerol_3_phosphate -> Glyceraldehyde_3_phosphate + Indole ( b1260 and b1261 ) Reaction Name: tyrosine transaminase Estimated Flux: -1.326138e-001 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + L_Tyrosine <=> 3__4_Hydroxyphenyl_pyruvate + L_Glutamate ( b4054 or b0928 ) Reaction Name: UDP 3 O 3 hydroxymyristoyl glucosamine acyltransferase Estimated Flux: 1.700696e-002 mmol gDW- 1 h- 1 Reaction Formula: R__3_Hydroxytetradecanoyl_acyl_carrier_protein + UDP_3_O__3_hydroxytetradecanoyl__D_glucosamine -> acyl_carrier_protein + H + UDP_2_3_bis_3_hydroxytetradecanoyl_glucosamine b0179 Reaction Name: UDP N acetylmuramoyl L alanyl D glutamyl meso 2 6 diaminopimelate synthetase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: meso_2_6_Diaminoheptanedioate + ATP + UDP_N_acetylmuramoyl_L_alanyl_D_glutamate -> ADP + H + Phosphate + UDP_N_acetylmuramoyl_L_alanyl_D_gamma_glutamyl_meso_2_6_diaminopimelate b0085 Reaction Name: UDP N acetylglucosamine acyltransferase Estimated Flux: 1.700696e-002 mmol gDW- 1 h- 1 Reaction Formula: R__3_Hydroxytetradecanoyl_acyl_carrier_protein + UDP_N_acetyl_D_glucosamine <=> acyl_carrier_protein + UDP_3_O__3_hydroxytetradecanoyl__N_acetylglucosamine b0181 Reaction Name: UDP N acetylglucosamine 1 carboxyvinyltransferase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: Phosphoenolpyruvate + UDP_N_acetyl_D_glucosamine -> Phosphate + UDP_N_acetyl_3_O__1_carboxyvinyl__D_glucosamine b3189 Reaction Name: UDP N acetylglucosamine diphosphorylase Estimated Flux: 7.288697e-002 mmol gDW- 1 h- 1 Reaction Formula: N_Acetyl_D_glucosamine_1_phosphate + H + UTP -> Diphosphate + UDP_N_acetyl_D_glucosamine b3730 Reaction Name: UDP N acetylglucosamine N acetylmuramyl pentapeptide pyrophosphoryl undecaprenol N acetylglucosamine transferase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: UDP_N_acetyl_D_glucosamine + Undecaprenyl_diphospho_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine -> H + Undecaprenyl_diphospho_N_acetylmuramoyl__N_acetylglucosamine__L_ala_D_glu_meso_2_6_diaminopimeloyl_D_ala_D_ala + UDP b0090 Reaction Name: UDP N acetylmuramoyl L alanyl D glutamate synthetase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + D_Glutamate + UDP_N_acetylmuramoyl_L_alanine -> ADP + H + Phosphate + UDP_N_acetylmuramoyl_L_alanyl_D_glutamate b0088 Reaction Name: UDP N acetylmuramoyl L alanine synthetase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: L_Alanine + ATP + UDP_N_acetylmuramate -> ADP + H + Phosphate + UDP_N_acetylmuramoyl_L_alanine b0091 Reaction Name: UDP N acetylenolpyruvoylglucosamine reductase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: H + Nicotinamide_adenine_dinucleotide_phosphate___reduced + UDP_N_acetyl_3_O__1_carboxyvinyl__D_glucosamine -> Nicotinamide_adenine_dinucleotide_phosphate + UDP_N_acetylmuramate b3972 Reaction Name: undecaprenyl diphosphatase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + Undecaprenyl_diphosphate -> H + Phosphate + Undecaprenyl_phosphate Reaction Name: Undecaprenyl diphosphate synthase Estimated Flux: 5.372751e-018 mmol gDW- 1 h- 1 Reaction Formula: Farnesyl_diphosphate + 8.000000 Isopentenyl_diphosphate -> 8.000000 Diphosphate + Undecaprenyl_diphosphate b0174 Reaction Name: UDP N acetylmuramoyl L alanyl D glutamyl meso 2 6 diaminopimeloyl D alanyl D alanine synthetase Estimated Flux: 2.794001e-002 mmol gDW- 1 h- 1 Reaction Formula: D_Alanyl_D_alanine + ATP + UDP_N_acetylmuramoyl_L_alanyl_D_gamma_glutamyl_meso_2_6_diaminopimelate -> ADP + H + Phosphate + UDP_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine b0086 Reaction Name: UDP 3 O acetylglucosamine deacetylase Estimated Flux: 1.700696e-002 mmol gDW- 1 h- 1 Reaction Formula: H2O + UDP_3_O__3_hydroxytetradecanoyl__N_acetylglucosamine -> Acetate + UDP_3_O__3_hydroxytetradecanoyl__D_glucosamine b0096 Reaction Name: UMP kinase Estimated Flux: 3.554252e-001 mmol gDW- 1 h- 1 Reaction Formula: ATP + UMP <=> ADP + UDP ( b0910 or b0171 ) Reaction Name: 2 keto 4 methylthiobutyrate transamination Estimated Flux: 7.086233e-003 mmol gDW- 1 h- 1 Reaction Formula: 2_keto_4_methylthiobutyrate + L_Glutamate -> 2_Oxoglutarate + L_Methionine Reaction Name: uridylate kinase dUMP Estimated Flux: -2.500428e-002 mmol gDW- 1 h- 1 Reaction Formula: ATP + dUMP <=> ADP + dUDP b0171 Reaction Name: UDP sugar hydrolase Estimated Flux: 8.503480e-003 mmol gDW- 1 h- 1 Reaction Formula: H2O + UDP_2_3_bis_3_hydroxytetradecanoyl_glucosamine -> 2.000000 H + 2_3_Bis_3_hydroxytetradecanoyl__beta_D_glucosaminyl_1_phosphate + UMP b0480 Reaction Name: valine transaminase Estimated Flux: 9.990152e+002 mmol gDW- 1 h- 1 Reaction Formula: 2_Oxoglutarate + L_Valine <=> 3_Methyl_2_oxobutanoate + L_Glutamate b3770 Reaction Name: Valine pyruvate aminotransferase Estimated Flux: 9.994222e+002 mmol gDW- 1 h- 1 Reaction Formula: 3_Methyl_2_oxobutanoate + L_Alanine -> Pyruvate + L_Valine b3572 Reaction Name: xanthine reversible transport Estimated Flux: -9.586543e-029 mmol gDW- 1 h- 1 Reaction Formula: Xanthine <=> Xanthine Reaction Name: xanthine phosphoribosyltransferase Estimated Flux: -3.762835e-028 mmol gDW- 1 h- 1 Reaction Formula: 5_Phospho_alpha_D_ribose_1_diphosphate + Xanthine -> Diphosphate + Xanthosine_5__phosphate b0238