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Team:Peking S
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Revision as of 08:59, 18 August 2011
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A ‘Chemical Wire’ Toolkit for Microbial Consortia in Synthetic Biology
Cell-cell communication-based multicellular networks provide an extended vista for synthetic biology. By compartmentalizing complex genetic circuits into separate engineered cells, the difficulty of the construction by layering elementary logic gates can be dramatically reduced, partly due to the insulation of crosstalk between modules, the suppression of noise by populationally averaging, and the reducing of metabolic burden in host cells. What’s more, cell-cell communication-based multicellular feature also enables coordination and synchronization among cells in and between populations and facilitates the generation of reliable non-Boolean dynamics.
Cell-cell communication-based multicellular networks provide an extended vista for synthetic biology. By compartmentalizing complex genetic circuits into separate engineered cells, the difficulty of the construction by layering elementary logic gates can be dramatically reduced, partly due to the insulation of crosstalk between modules, the suppression of noise by populationally averaging, and the reducing of metabolic burden in host cells. What’s more, cell-cell communication-based multicellular feature also enables coordination and synchronization among cells in and between populations and facilitates the generation of reliable non-Boolean dynamics.
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