Team:NYC Wetware/Deinococcus/Cell Damage

From 2011.igem.org

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<img src="http://images.wikia.com/genealogy/images/d/d8/Benzopyrene_DNA_adduct_1JDG.png" alt="oy" width="350" />
<img src="http://images.wikia.com/genealogy/images/d/d8/Benzopyrene_DNA_adduct_1JDG.png" alt="oy" width="350" />
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<img src="https://dl-web.dropbox.com/get/iGEM%202011%20Dropbox/pictures/DNAPic.png?w=0d1335e3" alt="oy" width="350" /><br/>
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<img src="https://dl-web.dropbox.com/get/iGEM%20pics/DNAPic.png?w=97200b44" alt="oy" width="350" /><br/>
<h3>Damage to the DNA and Proteins</h3>
<h3>Damage to the DNA and Proteins</h3>
The cell is hit repeatedly with radiation, causing extensive damage to the DNA and proteins. The damage to the DNA includes:<br/>
The cell is hit repeatedly with radiation, causing extensive damage to the DNA and proteins. The damage to the DNA includes:<br/>
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1. Base Damage <img src="https://dl-web.dropbox.com/get/iGEM%202011%20Dropbox/pictures/Base%2520Damage.png?w=1907c82a" alt="oy" width="350" /> <br/>
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1. Base Damage <img src="https://dl-web.dropbox.com/get/iGEM%20pics/Base%2520Damage.png?w=4cf155c6" alt="oy" width="350" /> <br/>
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DNA is composed of a backbone attached to nucleobases. Damage may occur to the bases.<br/>
DNA is composed of a backbone attached to nucleobases. Damage may occur to the bases.<br/>
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2. Single Strand Breaks <img src="https://dl-web.dropbox.com/get/iGEM%202011%20Dropbox/pictures/SSb.png?w=47783347" alt="oy" width="350" /><br/>
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2. Single Strand Breaks <img src="https://dl-web.dropbox.com/get/iGEM%20pics/SSb.png?w=4ce7f8e9" alt="oy" width="350" /><br/>
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The backbone of DNA is made up of a repeating pattern of sugar and phosphate. A single strand break occurs when this backbone is broken.<br/>
The backbone of DNA is made up of a repeating pattern of sugar and phosphate. A single strand break occurs when this backbone is broken.<br/>
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3. Double Strand Breaks<img src="https://dl-web.dropbox.com/get/iGEM%202011%20Dropbox/pictures/DSb.png?w=631620b0" alt="oy" width="350" /> <br/>
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3. Double Strand Breaks<img src="https://dl-web.dropbox.com/get/iGEM%20pics/DSb.png?w=fa98fc0d" alt="oy" width="350" /> <br/>
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DNA is commonly found as a double strand. If the opposing strands both develop single strand breaks, this double strand break may cause the separation of the two fragments of DNA.<br/>
DNA is commonly found as a double strand. If the opposing strands both develop single strand breaks, this double strand break may cause the separation of the two fragments of DNA.<br/>
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Ionizing radiation is radiation with sufficient energy to remove an electron from an atom.<br/>
Ionizing radiation is radiation with sufficient energy to remove an electron from an atom.<br/>
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<img src="https://dl-web.dropbox.com/get/iGEM%20pics/ElectromagSpec.jpg?w=afee9db2" alt="oy" width="600" /><br/>  
It has the power to cause Double Strand Breaks, as well as initiate the Fenton Reaction, which can cause damage to proteins as well as DNA.<br/>
It has the power to cause Double Strand Breaks, as well as initiate the Fenton Reaction, which can cause damage to proteins as well as DNA.<br/>
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Revision as of 13:41, 12 October 2011