Team:NYC Wetware

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<title>NYC-iGEM wetware</title>
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<h3>Our Team</h3>
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<b>Awarded Bronze Medal</b><br>
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<b>Won Best Human Practices Advance, Americas</b></br>
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<b>Featured on the <a href="http://area.autodesk.com/blogs/cory/maya_nyc_and_igem"> Autodesk Blog</a></b></br>
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<b>Check out our Presentation at the Jamboree. Enjoy!</b></br>
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<h4> Radiation-resistance? There's a Gene for That. </h4>
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Our iGEM squadron consists of students from the Dalton School, Hunter College, Columbia University, Yeshiva University, NYU-Poly, and Cornell University. Our advisors (and donated workspace) reside at Weill Cornell Medical College on the Upper East Side of Manhattan. Briefly, over the summer we will be investigating the genetic mechanisms for ionizing radiation resistance in Deinococcus radiodurans through genome sequencing, RNA-sequencing experiments, and high throughput cloning.  
Our iGEM squadron consists of students from the Dalton School, Hunter College, Columbia University, Yeshiva University, NYU-Poly, and Cornell University. Our advisors (and donated workspace) reside at Weill Cornell Medical College on the Upper East Side of Manhattan. Briefly, over the summer we will be investigating the genetic mechanisms for ionizing radiation resistance in Deinococcus radiodurans through genome sequencing, RNA-sequencing experiments, and high throughput cloning.  
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<h3>Our Approach</h3>
<h3>Our Approach</h3>
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We've been following the literature on two approaches to describing the particulars of D. rad's radioresisitance: <br>
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We've been examining the literature on different approaches to explaining Deinococcus radiodurans' radioresistance: <br>
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1. DNA Repair - Dr John Battista's work has focused on the rapid DNA repair mechanisms of D. rad and their attendant proteins as the responsible parties for it extraordinary radioresistance. <p>
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1. DNA Repair - Dr. John Battista's work has focused on the rapid DNA repair mechanisms of D. rad and their attendant proteins as the responsible parties for its extraordinary radioresistance. <p>
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2. Iron-Manganaese Ratios - Dr Michael Daly's research suggests that D. rad uses manganese as an antioxidant to fight radiation damage. <p>
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2. Cellular Metabolome - Dr. Michael Daly's research suggests that the higher Manganese to Iron Ratio in D. rad increases antioxidant properties in the cells and reduces damage from radiative events. <p>
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3. Neutralization of superoxide radicals - the Superoxide Dismutase / Catalase system has been shown to neutralize damaging oxygen radicals in a variety of species from Humans to Wheat.
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<h3>Our Considerations</h3>
<h3>Our Considerations</h3>
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Ordering lunch for our team was one of the more difficult protocols to follow. With our mix of kosher-eaters, vegans, and vegetarians, making menu selections was no simple matter. It dawned on us to discuss the relationship of synthetic biology to food ethics. Is laboratory-grown meat kosher? Is it vegan? What do authorities from both traditions have to say about the matter? While in vitro meat is still a prospect of the somewhat distant future, cheese is already being made from animal enzymes that are being synthesized by transformed bacteria. How have the kosher and vegan communities responded to these innovations?  
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Ordering lunch for our team was more difficult than any other protocols we developed. With our mix of kosher-eaters, vegans, and vegetarians, making menu selections was no simple matter. It dawned on us to discuss the relationship of synthetic biology to food ethics. Is laboratory-grown meat kosher? Is it vegan? What do authorities from both traditions have to say about the matter? While in vitro meat is still a prospect of the somewhat distant future, cheese is already being made from animal enzymes that are being synthesized by transformed bacteria. How have the kosher and vegan communities responded to these innovations?  
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<h3>Yeshiva University Wetlab Team Members</h3>
 
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Jake Friedman<p>
 
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David Sweet<p>
 
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Yossi Steinberger<p>
 
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Yair Saperstein<p>
 
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<h3>Weill Cornell Medical Grad Students + Faculty Advisors</h3>
 
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Russell Durrett, Christopher Mason PhD - Institute for Computational Biology <p>
 
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Alex Hansler, Steven Gross PhD - Department of Pharmacology
 
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<h3>Sponsors</h3>
 
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<li>Illumina
 
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<li>Agilent
 
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<li>Science House
 
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<li>Quartzy
 
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<li>Integrated DNA Technologies
 
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<!--- The Mission, Experiments --->
 
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
 
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!align="center"|[[Team:NYC_Wetware|Home]]
 
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!align="center"|[[Team:NYC_Wetware/Team|Team]]
 
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!align="center"|[https://igem.org/Team.cgi?year=2011&team_name=NYC_Wetware Official Team Profile]
 
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!align="center"|[[Team:NYC_Wetware/Project|Project]]
 
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!align="center"|[[Team:NYC_Wetware/Parts|Parts Submitted to the Registry]]
 
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!align="center"|[[Team:NYC_Wetware/Modeling|Modeling]]
 
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!align="center"|[[Team:NYC_Wetware/Notebook|Notebook]]
 
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!align="center"|[[Team:NYC_Wetware/Safety|Safety]]
 
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!align="center"|[[Team:NYC_Wetware/Attributions|Attributions]]
 
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Latest revision as of 19:12, 30 November 2011